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Yusuf Hamied Department of Chemistry

 

Publications by Professor David Spring

Diversity-Oriented Synthesis of Macrocycle Libraries for Drug Discovery and Chemical Biology
S Collins, S Bartlett, F Nie, HF Sore, DR Spring
– Synthesis
(2016)
48,
1457
(DOI: 10.1055/s-0035-1561414)
Development of a Multifunctional Benzophenone Linker for Peptide Stapling and Photoaffinity Labelling.
Y Wu, LB Olsen, YH Lau, CH Jensen, M Rossmann, YR Baker, HF Sore, S Collins, DR Spring
– ChemBioChem
(2016)
17,
689
(DOI: 10.1002/cbic.201500648)
Divergent Total Syntheses of Flavonoid Natural Products Isolated from Rosa rugosa and Citrus unshiu
TJ Sum, TH Sum, WRJD Galloway, DR Spring
– Synlett
(2016)
27,
1725
(DOI: 10.1055/s-0035-1561851)
Structure of the Stapled Peptide Bound to Mdm2
YH Lau, Y Wu, M Rossmann, P de Andrade, YS Tan, GJ McKenzie, AR Venkitaraman, M Hyvonen, DR Spring
(2016)
(DOI: 10.2210/pdb5afg/pdb)
A new Pseudomonas quinolone signal (PQS) binding partner: MexG
JT Hodgkinson, J Gross, YR Baker, DR Spring, M Welch
– Chemical Science
(2016)
7,
2553
(DOI: 10.1039/c5sc04197j)
Synthesis of diverse semi-saturated bicyclic heteroaromatics
H Stewart, D Spring, T Moss
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
252,
NEW ADVANCES IN DIVERSITY-ORIENTED SYNTHESIS
WRJD Galloway, JE Stokes, DR Spring
(2016)
79
Divergent synthesis of six biologically active 4-quinolone natural products isolated from Pseudonocardia sp CL38489
S Geddis, D Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
252,
Targeting transcription factor HNF1β in ovarian cancer using stapled peptides
M Wiedmann, D Spring, J Brenton
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
251,
The reductive cleavage of picolinic amides
DH O'Donovan, C De Fusco, DR Spring
– Tetrahedron Letters
(2016)
57,
2962
(DOI: 10.1016/j.tetlet.2016.05.068)
Partially saturated heteroaromatics as an sp3 enriched fragment collection
S Mitchell, D Twigg, N Kondo, D Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2016)
252,
The synthesis of quinolone natural products from pseudonocardia sp.
F Salvaggio, JT Hodgkinson, L Carro, SM Geddis, WRJD Galloway, M Welch, DR Spring
– European journal of organic chemistry
(2015)
2016,
434
(DOI: 10.1002/ejoc.201501400)
Concise synthesis of rare pyrido[1,2-<i>a</i>]pyrimidin-2-ones and related nitrogen-rich bicyclic scaffolds with a ring-junction nitrogen
TA Alanine, WRJD Galloway, S Bartlett, JJ Ciardiello, TM McGuire, DR Spring
– Organic and Biomolecular Chemistry
(2015)
14,
1031
(DOI: 10.1039/c5ob01784j)
Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides.
YH Lau, Y Wu, M Rossmann, BX Tan, P de Andrade, YS Tan, C Verma, GJ McKenzie, AR Venkitaraman, M Hyvönen, DR Spring
– Angewandte Chemie International Edition
(2015)
54,
15410
(DOI: 10.1002/anie.201508416)
Double Strain‐Promoted Macrocyclization for the Rapid Selection of Cell‐Active Stapled Peptides
YH Lau, Y Wu, M Rossmann, BX Tan, P de Andrade, YS Tan, C Verma, GJ McKenzie, AR Venkitaraman, M Hyvönen, DR Spring
– Angewandte Chemie
(2015)
127,
15630
(DOI: 10.1002/ange.201508416)
Which microbial factors really are important in <i>Pseudomonas aeruginosa</i> infections?
A Crousilles, E Maunders, S Bartlett, C Fan, E-F Ukor, Y Abdelhamid, Y Baker, A Floto, DR Spring, M Welch
– Future microbiology
(2015)
10,
1825
(DOI: 10.2217/fmb.15.100)
New Advances in Diversity-Oriented Synthesis
WRJD Galloway, JE Stokes, DR Spring
(2015)
77
(DOI: 10.1002/9781118771723.ch4)
The Application of Ligand-Mapping Molecular Dynamics Simulations to the Rational Design of Peptidic Modulators of Protein-Protein Interactions.
YS Tan, DR Spring, C Abell, CS Verma
– J Chem Theory Comput
(2015)
11,
3199
(DOI: 10.1021/ct5010577)
Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.
L Laraia, G McKenzie, DR Spring, AR Venkitaraman, DJ Huggins
– Chem Biol
(2015)
22,
689
(DOI: 10.1016/j.chembiol.2015.04.019)
Studies towards the synthesis of indolizin-5(3H)-one derivatives and related 6,5-azabicyclic scaffolds by ring-closing metathesis
MS Frei, MK Bilyard, TA Alanine, WRJD Galloway, JE Stokes, DR Spring
– Bioorganic and Medicinal Chemistry
(2015)
23,
2666
(DOI: 10.1016/j.bmc.2014.11.037)

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