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Yusuf Hamied Department of Chemistry

 

Recent Publications from the Synthesis Research Interest Group

Continuous Flow Techniques in the Total Synthesis of Jaspine B: Part II.
M Gurský, D Trnovcová, P Lopatka, M Markovič, P Koóš, SV Ley, T Gracza
– The Journal of Organic Chemistry
(2025)
acs.joc.5c01799
(DOI: 10.1021/acs.joc.5c01799)
β-Lactamase cleavable antimicrobial peptide–drug conjugates
T Deingruber, JS Gaynord, BH Gan, KA Kostadinova, TJ O'Brien, YS Tan, JS Parker, TA Hunt, JS Carroll, M Welch, DR Spring
– Chemical science
(2025)
(DOI: 10.1039/d5sc06369h)
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, EJ Fisher, M Zacharopoulou, F Ferrer, D Barford, DR Spring, C Lindon, C Phillips, LS Itzhaki
– eLife
(2025)
14,
RP104238
(DOI: 10.7554/elife.104238.3)
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, EJ Fisher, M Zacharopoulou, F Ferrer, D Barford, DR Spring, C Lindon, C Phillips, LS Itzhaki
(2025)
(DOI: 10.7554/eLife.104238)
A Dynamic Silver(I) Nanocluster Holds Together a 3 × 3 Self-Assembled Grid
AW Heard, L Pesce, PT Gierth, S Adorinni, TK Ronson, B Rossi, JD Thoburn, T Deingruber, M Welch, DR Spring, S Marchesan, GM Pavan, JR Nitschke
– J Am Chem Soc
(2025)
147,
30842
(DOI: 10.1021/jacs.5c07271)
Selective endo-Cyclic α‑Functionalization of Saturated N‑Alkyl Piperidines
RC Phillips, JCK Chu, AA Rafaniello, MJ Gaunt
– Journal of Organic Chemistry
(2025)
90,
12226
(DOI: 10.1021/acs.joc.5c01742)
Chirality-Assisted Self-Assembly of Low-Symmetry Noncovalent Capsules with Quantitative Diastereoisomeric Selection
G Markiewicz, X Qiu, G Avci, EH Wolpert, KE Jelfs, JKM Sanders, AR Stefankiewicz
– Journal of the American Chemical Society
(2025)
147,
31270
(DOI: 10.1021/jacs.5c10523)
Templated-Directed Ligation of Recognition-Encoded Melamine Oligomers
LA Beale, JT Smith, CJ Anderson, ON Evans, CA Hunter
– Chemical Science
(2025)
16,
15991
(DOI: 10.1039/d5sc05650k)
Allylic Amination of Alkenyl Alcohols: Simultaneous Control of Chemoselectivity and Enantioselectivity in Nitrene Transfer Using Ion-Paired Catalysts
HK Adams, A Fanourakis, A Dahiya, I Băltăreţu, RJ Phipps
– ACS Catalysis
(2025)
15,
14639
(DOI: 10.1021/acscatal.5c04140)
Structural and Gas Uptake Studies on Iron(II) β‑Diketiminate Metallomacrocycles.
AN Barrett, L Webster, D Gasperini, R Castaing, MF Mahon, RL Webster
– Organometallics
(2025)
44,
1713
(DOI: 10.1021/acs.organomet.5c00208)
Structural and Gas Uptake Studies on Iron(II) β-Diketiminate Metallomacrocycles
AN Barrett, L Webster, D Gasperini, R Castaing, MF Mahon, RL Webster
– Organometallics
(2025)
44,
1713
(DOI: 10.1021/acs.organomet.5c00208)
Intercepting Methanimine for the Synthesis of Piperidine-Based <i>N</i>-Heterocycles in an Aqueous Medium
E Pocock, M Diefenbach, TM Hood, M Nunn, V Krewald, SE Lewis, RL Webster
– J Org Chem
(2025)
90,
11257
(DOI: 10.1021/acs.joc.5c01213)
Supramolecular Assembly Properties of a Mixed-Sequence Recognition-Encoded Melamine Oligomer
M Dhiman, JT Smith, CA Hunter
– Organic and Biomolecular Chemistry
(2025)
23,
6948
(DOI: 10.1039/d5ob00769k)
Enantioselective Formal Synthesis of (−)-Aflatoxin B2Enabled by Pd-Catalyzed Carboetherification of 2,3-Dihydrofuran
M Kadarauch, RJ Phipps
– Organic letters
(2025)
27,
8344
(DOI: 10.1021/acs.orglett.5c02618)
Detecting alpha-synuclein aggregates with small molecules on single-molecule array
JYL Lam, TS Chisholm, H Almahli, EA English, Z Xia, Y Wu, MR Cheetham, CA Hunter, D Klenerman
– Chemical science
(2025)
16,
13435
(DOI: 10.1039/d4sc07649d)
Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
– Angewandte Chemie International Edition
(2025)
64,
e202507532
(DOI: 10.1002/anie.202507532)
Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
– Angewandte Chemie
(2025)
137,
e202507532
(DOI: 10.1002/ange.202507532)
Asymmetric Aziridination of Allylic Carbamates Using Ion-Paired Rhodium Complexes and Extrapolation to C―H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
– Angewandte Chemie International Edition
(2025)
64,
e202507532
(DOI: 10.1002/anie.202507532)
Prediction of solution phase association constants by mapping contact points in intermolecular complexes.
KJ Zator, CA Hunter
– Phys Chem Chem Phys
(2025)
27,
11343
(DOI: 10.1039/d5cp00398a)
Dehomologative C-C Borylation of Aldehydes and Alcohols via a Rh-Catalyzed Dehydroformylation-Borylation Relay.
K Das, N Kuźnik, P Dydio
– Journal of the American Chemical Society
(2025)
147,
16735
(DOI: 10.1021/jacs.5c02181)

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