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Recent Publications from the Synthesis Research Interest Group

Visible-Light-Mediated Annulation of Electron-Rich Alkenes and Nitrogen-Centered Radicals from N-Sulfonylallylamines: Construction of Chloromethylated Pyrrolidine Derivatives.
LNS Crespin, A Greb, DC Blakemore, SV Ley
– The Journal of organic chemistry
(2017)
Stereocontrolled Semisyntheses of Elliptone and 12aβ-Hydroxyelliptone.
DA Russell, WJS Fong, DG Twigg, HF Sore, DR Spring
– Journal of natural products
(2017)
80,
2751
meta-Selective C−H Borylation of Benzylamine-, Phenethylamine-, and Phenylpropylamine-Derived Amides Enabled by a Single Anionic Ligand
HJ Davis, GR Genov, RJ Phipps
– Angewandte Chemie
(2017)
129,
13536
Sequence-Selective Formation of Synthetic H-Bonded Duplexes
AE Stross, G Iadevaia, D Núñez-Villanueva, CA Hunter
– Journal of the American Chemical Society
(2017)
139,
12655
Triggered release from lipid bilayer vesicles by an artificial transmembrane signal transduction system
MJ Langton, LM Scriven, NH Williams, CA Hunter
– Journal of the American Chemical Society
(2017)
139,
15768
meta-Selective C-H Borylation of Benzylamine-, Phenethylamine-, and Phenylpropylamine-Derived Amides Enabled by a Single Anionic Ligand.
HJ Davis, GR Genov, RJ Phipps
– Angew Chem Int Ed Engl
(2017)
56,
13351
Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines
R Labes, D González-Calderón, C Battilocchio, C Mateos, GR Cumming, O de Frutos, JA Rincón, SV Ley
– Synlett
(2017)
28,
Highlights from the 52nd EUCHEM conference on stereochemistry, Bürgenstock, Switzerland, May 2017.
J Montenegro, RJ Phipps
– Chemical communications (Cambridge, England)
(2017)
53,
9960
Computationally-guided optimization of small-molecule inhibitors of the Aurora A kinase-TPX2 protein-protein interaction.
DJ Cole, M Janecek, JE Stokes, M Rossmann, JC Faver, GJ McKenzie, AR Venkitaraman, M Hyvönen, DR Spring, DJ Huggins, WL Jorgensen
– Chemical communications (Cambridge, England)
(2017)
53,
9372
Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design
Y Wu, F Villa, J Maman, YH Lau, L Dobnikar, AC Simon, K Labib, DR Spring, L Pellegrini
– Angew Chem Int Ed Engl
(2017)
56,
12866
Chemoselective Continuous Ru-Catalyzed Hydrogen-Transfer Oppenauer-Type Oxidation of Secondary Alcohols
R Labes, C Battilocchio, C Mateos, GR Cumming, O De Frutos, JA Rincón, K Binder, SV Ley
– Organic Process Research and Development
(2017)
21,
1419
Transfer hydrogenation of ortho-hydroxybenzophenone ketimines catalysed by BINOL-derived phosphoric acid occurs by a 14-membered bifunctional transition structure
JP Reid, JM Goodman
– Org. Biomol. Chem.
(2017)
15,
6943
Induction of accelerated senescence by the microtubule-stabilizing agent peloruside A.
A Chan, C Gilfillan, N Templeton, I Paterson, PT Northcote, JH Miller
– Invest New Drugs
(2017)
35,
706
Cocrystals of spironolactone and griseofulvin based on an in silico screening method
T Grecu, R Prohens, JF McCabe, EJ Carrington, JS Wright, L Brammer, CA Hunter
– CrystEngComm
(2017)
19,
3592
A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
C De Fusco, P Brear, J Iegre, KH Georgiou, HF Sore, M Hyvönen, DR Spring
– Bioorganic & medicinal chemistry
(2017)
25,
3471
Enantioselective Copper-Catalyzed Arylation-Driven Semipinacol Rearrangement of Tertiary Allylic Alcohols with Diaryliodonium Salts.
DH Lukamto, MJ Gaunt
– Journal of the American Chemical Society
(2017)
139,
9160
Enantioselective Copper-Catalyzed Arylation-driven Semi-Pinacol Rearrangement of Allylic Alcohols with Diaryliodonium Salts
DH Lukamto, MJ Gaunt
– Journal of the American Chemical Society
(2017)
Unveiling the role of boroxines in metal-free carbon-carbon homologations using diazo compounds and boronic acids
C Bomio, MA Kabeshov, AR Lit, SH Lau, J Ehlert, C Battilocchio, SV Ley
– Chem. Sci.
(2017)
8,
6071
Flow synthesis of cyclobutanones \textit{via} [2 + 2] cycloaddition of keteneiminium salts and ethylene gas
C Battilocchio, G Iannucci, S Wang, E Godineau, A Krieger, MA De, SV Ley
– Reaction Chemistry & Engineering
(2017)
2,
295
Divergent synthesis of biflavonoids yields novel inhibitors of the aggregation of amyloid β (1-42)
TH Sum, TJ Sum, S Collins, WRJD Galloway, DG Twigg, F Hollfelder, DR Spring
– Org. Biomol. Chem.
(2017)
15,
4554