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Recent Publications from the Synthesis Research Interest Group

A Synthetic Vesicle-to-Vesicle Communication System.
Y Ding, NH Williams, CA Hunter
– Journal of the American Chemical Society
(2019)
141,
17847
(DOI: 10.1021/jacs.9b09102)
A practical method for continuous production of sp3‐rich compounds from (hetero)aryl halides and redox‐active esters
Y Chen, E Watanabe, O May, SV Ley
– Chemistry: A European Journal
(2019)
chem.201905048
(DOI: 10.1002/chem.201905048)
Rapid syntheses of (−)-FR901483 and (+)-TAN1251C enabled by complexity-generating photocatalytic olefin hydroaminoalkylation
MJ Gaunt, D Reich, A Trowbridge
– Angewandte Chemie International Edition
(2019)
(DOI: 10.1002/anie.201912010)
Molecular replication using covalent base-pairs with traceless linkers
D Núñez-Villanueva, CA Hunter
– Organic and Biomolecular Chemistry
(2019)
(DOI: 10.1039/c9ob02336d)
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation
P Sharma, R Mahen, M Rossmann, JE Stokes, B Hardwick, DJ Huggins, A Emery, DL Kunciw, M Hyvönen, DR Spring, GJ McKenzie, AR Venkitaraman
– Scientific Reports
(2019)
9,
15930
(DOI: 10.1038/s41598-019-50702-2)
A New World for Chemical Synthesis?
SV Ley, Y Chen, DE Fitzpatrick, O May
– Chimia
(2019)
73,
792
(DOI: 10.2533/chimia.2019.792)
Continuous Pd-Catalyzed Carbonylative Cyclization Using Iron Pentacarbonyl as a CO Source.
P Lopatka, M Markovič, P Koóš, SV Ley, T Gracza
– The Journal of organic chemistry
(2019)
acs.joc.9b02453
(DOI: 10.1021/acs.joc.9b02453)
Direct Synthesis of N-Functionalized Dipropargylamine Linkers as Models for Use in Peptide Stapling
A Renzetti, RN Rutherford, K Fukumoto, D Kunciw, HF Sore, DR Spring
– Synlett
(2019)
(DOI: 10.1055/s-0039-1690217)
Ion-Pair-Directed Borylation of Aromatic Phosphonium Salts.
B Lee, MT Mihai, V Stojalnikova, RJ Phipps
– The Journal of Organic Chemistry
(2019)
84,
13124
(DOI: 10.1021/acs.joc.9b00878)
An Activatable Cancer-Targeted Hydrogen Peroxide Probe for Photoacoustic and Fluorescence Imaging.
J Weber, L Bollepalli, AM Belenguer, MD Antonio, N De Mitri, J Joseph, S Balasubramanian, CA Hunter, SE Bohndiek
– Cancer Res
(2019)
79,
5407
(DOI: 10.1158/0008-5472.CAN-19-0691)
Gaining insight into toxicity predicting machine learning algorithms
TEH Allen, E Gelzinyte, AJ Wedlake, JM Goodman, S Gutsell, PJ Russell
– TOXICOLOGY LETTERS
(2019)
314,
S280
Stereocontrolled Synthesis as an Enabling Tool for the Configurational Assignment of Marine Polyketide Natural Products
NYS Lam, I Paterson
– European Journal of Organic Chemistry
(2019)
(DOI: 10.1002/ejoc.201901243)
Para-Selective C-H Borylation of Common Arene Building Blocks Enabled by Ion-Pairing with a Bulky Countercation
MT Mihai, BD Williams, RJ Phipps
– J Am Chem Soc
(2019)
141,
15477
(DOI: 10.1021/jacs.9b07267)
Molecular Transformer: A Model for Uncertainty-Calibrated Chemical Reaction Prediction
P Schwaller, T Laino, T Gaudin, P Bolgar, CA Hunter, C Bekas, AA Lee
– ACS Cent Sci
(2019)
5,
1572
(DOI: 10.1021/acscentsci.9b00576)
Cap control: cyclic versus linear oligomerisation in covalent template-directed synthesis.
D Núñez-Villanueva, M Ciaccia, CA Hunter
– RSC Advances
(2019)
9,
29566
(DOI: 10.1039/c9ra07233k)
Cycloaddition Strategies for the Synthesis of Diverse Heterocyclic Spirocycles for Fragment-Based Drug Discovery
TA King, HL Stewart, KT Mortensen, AJP North, HF Sore, DR Spring
– European Journal of Organic Chemistry
(2019)
2019,
5219
(DOI: 10.1002/ejoc.201900847)
Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry.
K Sharma, AV Strizhak, E Fowler, X Wang, W Xu, C Hatt Jensen, Y Wu, HF Sore, YH Lau, M Hyvönen, LS Itzhaki, DR Spring
– Organic and Biomolecular Chemistry
(2019)
17,
8014
(DOI: 10.1039/c9ob01745c)
Cleavable linkers in antibody–drug conjugates
JD Bargh, A Isidro-Llobet, JS Parker, DR Spring
– Chem Soc Rev
(2019)
48,
4361
(DOI: 10.1039/c8cs00676h)
Bulk synthesis of graphene-like materials possessing turbostratic graphite and graphene nanodomains via combustion of magnesium in carbon dioxide
TH Kim, CR Merritt, C Ducati, AD Bond, N Bampos, CL Brown
– Carbon
(2019)
149,
582
(DOI: 10.1016/j.carbon.2019.04.035)
A counterintuitive stereochemical outcome from a chelation-controlled vinylmetal aldehyde addition leads to the configurational reassignment of phormidolide A
NYS Lam, G Muir, VR Challa, R Britton, I Paterson
– Chemical Communications
(2019)
55,
9717
(DOI: 10.1039/c9cc05067a)

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