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Department of Chemistry

 
A tutored discourse on microcontrollers, single board computers and their applications to monitor and control chemical reactions
DE Fitzpatrick, M O'Brien, SV Ley
– Reaction Chemistry & Engineering
(2020)
5,
201
Rapid Syntheses of (-)-FR901483 and (+)-TAN1251C Enabled by Complexity-Generating Photocatalytic Olefin Hydroaminoalkylation.
D Reich, A Trowbridge, MJ Gaunt
– Angewandte Chemie (International ed. in English)
(2020)
59,
2256
Sulfatase-cleavable linkers for antibody-drug conjugates
JD Bargh, SJ Walsh, A Isidro-Llobet, S Omarjee, JS Carroll, DR Spring
– Chemical Science
(2020)
Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction
K Sharma, AV Strizhak, E Fowler, W Xu, B Chappell, HF Sore, WRJD Galloway, MN Grayson, YH Lau, LS Itzhaki, DR Spring
– ACS omega
(2020)
5,
1157
A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti‐Trypanosomal Macrolides
MJ Anketell, TM Sharrock, I Paterson
– Angewandte Chemie
(2020)
132,
1588
Editorial 2020: Changing publishing and academic culture
JKM Sanders
– Royal Society Open Science
(2020)
7,
192197
Development of a Novel Cell-Permeable Protein-Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1
DJ Huggins, BS Hardwick, P Sharma, A Emery, L Laraia, F Zhang, AJ Narvaez, M Roberts-Thomson, AT Crooks, RG Boyle, R Boyce, DW Walker, N Mateu, GJ McKenzie, DR Spring, AR Venkitaraman
– ACS omega
(2020)
5,
822
Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents.
TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, JS Parker, DR Spring, I Paterson
– Chemical communications (Cambridge, England)
(2020)
56,
1529
A Practical Method for Continuous Production of sp3-Rich Compounds from (Hetero)Aryl Halides and Redox-Active Esters.
E Watanabe, Y Chen, O May, SV Ley
– Chemistry
(2020)
26,
186
Catalytic C(sp3)-H bond activation in tertiary alkylamines.
J Rodrigalvarez, M Nappi, H Azuma, NJ Flodén, ME Burns, MJ Gaunt
– Nature Chemistry
(2020)
12,
76
Structural Alerts and Random Forest Models in a Consensus Approach for Receptor Binding Molecular Initiating Events.
AJ Wedlake, M Folia, S Piechota, TEH Allen, JM Goodman, S Gutsell, PJ Russell
– Chemical Research in Toxicology
(2020)
acs.chemrestox.9b00325
Fsp3-rich and diverse fragments inspired by natural products as a collection to enhance fragment-based drug discovery
AR Hanby, NS Troelsen, TJ Osberger, SL Kidd, KT Mortensen, DR Spring
– Chem Commun (Camb)
(2020)
Quantitative Predictions for Molecular Initiating Events using 3D Quantitative Structure-Activity Relationships.
TEH Allen, JM Goodman, S Gutsell, PJ Russell
– Chemical Research in Toxicology
(2019)
acs.chemrestox.9b00136
Predictive Multivariate Linear Regression Analysis Guides Successful Catalytic Enantioselective Minisci Reactions of Diazines
JP Reid, RSJ Proctor, MS Sigman, RJ Phipps
– J Am Chem Soc
(2019)
141,
19178
Two-component assembly of recognition-encoded oligomers that form stable H-bonded duplexes.
L Gabrielli, D Núñez-Villanueva, CA Hunter
– Chemical Science
(2020)
11,
561
A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti-Trypanosomal Macrolides.
MJ Anketell, TM Sharrock, I Paterson
– Angewandte Chemie International Edition
(2020)
59,
1572
A Synthetic Vesicle-to-Vesicle Communication System
Y Ding, NH Williams, CA Hunter
– J Am Chem Soc
(2019)
141,
17847
Molecular replication using covalent base-pairs with traceless linkers
D Núñez-Villanueva, CA Hunter
– Organic & Biomolecular Chemistry
(2019)
17,
9660
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation
P Sharma, R Mahen, M Rossmann, JE Stokes, B Hardwick, DJ Huggins, A Emery, DL Kunciw, M Hyvönen, DR Spring, GJ McKenzie, AR Venkitaraman
– Sci Rep
(2019)
9,
15930
A New World for Chemical Synthesis?
SV Ley, Y Chen, DE Fitzpatrick, O May
– CHIMIA International Journal for Chemistry
(2019)
73,
792