Publications | Yusuf Hamied Department of Chemistry

Synthesis of sp<sup>3</sup>-rich heterocyclic frameworks by a divergent synthesis strategy

KT Mortensen, DSY Wong, TA King, HF Sore, DR Spring

– Organic & Biomolecular Chemistry

(2023)

(DOI: 10.1039/d3ob00351e)

Selective Functionalisation of 5‐Methylcytosine by Organic Photoredox Catalysis

MM Simpson, CC Lam, JM Goodman, S Balasubramanian

– Angewandte Chemie

(2023)

(DOI: 10.1002/ange.202304756)

Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis.

MM Simpson, CC Lam, JM Goodman, S Balasubramanian

– Angewandte Chemie International Edition

(2023)

e202304756

(DOI: 10.1002/anie.202304756)

Development of constrained peptide inhibitors targeting an oncogenic E3 ubiquitin ligase

G Zenkevičiūtė, W Xu, J Iegre, H Seki, YS Tan, PJE Rowling, F Ferrer, C Verma, D Spring, H Laman, L Itzhaki

(2023)

(DOI: 10.1101/2023.04.27.535981)

Substrate-Directed Enantioselective Aziridination of Alkenyl Alcohols Controlled by a Chiral Cation.

R Phipps, A Fanourakis, N Hodson, A Lit

– J Am Chem Soc

(2023)

145,

7516

(DOI: 10.1021/jacs.3c00693)

Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents

SR Stockwell, DE Scott, G Fischer, E Guarino, TPC Rooney, T-S Feng, T Moschetti, R Srinivasan, E Alza, A Asteian, C Dagostin, A Alcaide, M Rocaboy, B Blaszczyk, A Higueruelo, X Wang, M Rossmann, TR Perrior, TL Blundell, DR Spring, G McKenzie, C Abell, J Skidmore, M Hyvönen, AR Venkitaraman

(2023)

(DOI: 10.1101/2023.03.22.533679)

Interpreting vibrational circular dichroism spectra: the Cai center dot factor for absolute configuration with confidence

J Goodman, RJ Lewis, J Lam

– J Cheminform

(2023)

15,

(DOI: 10.1186/s13321-023-00706-y)

Scalable Palladium-Catalyzed C(sp3)-H Carbonylation of Alkylamines in Batch and Continuous Flow

J Zakrzewski, P Yaseneva, CJ Taylor, MJ Gaunt, AA Lapkin

– Organic Process Research & Development

(2023)

27,

649

(DOI: 10.1021/acs.oprd.2c00378)

Quantitative in Silico Prediction of the Rate of Protodeboronation by a Mechanistic Density Functional Theory-Aided Algorithm

DS Wigh, M Tissot, P Pasau, JM Goodman, AA Lapkin

– J Phys Chem A

(2023)

127,

2628

(DOI: 10.1021/acs.jpca.2c08250)

Recognition-Encoded Synthetic Information Molecules

G Iadevaia, CA Hunter

– Acc Chem Res

(2023)

56,

712

(DOI: 10.1021/acs.accounts.3c00029)

A Recombinant Approach For Stapled Peptide Discovery Yields Inhibitors of the RAD51 Recombinase

T Pantelejevs, P Zuazua-Villar, O Koczy, A Counsell, S Walsh, N Robertson, D Spring, J Downs, M Hyvönen

(2023)

(DOI: 10.1101/2023.02.24.529929)

The human proton pump inhibitors inhibit Mycobacterium tuberculosis rifampicin efflux, and macrophage-induced rifampicin tolerance

MA Lake, KN Adams, F Nie, E Fowler, AK Verma, S Dei, E Teodori, DR Sherman, PH Edelstein, DR Spring, M Troll, L Ramakrishnan

– Proceedings of the National Academy of Sciences

(2023)

120,

e2215512120

(DOI: 10.1073/pnas.2215512120)

Peroxide-cleavable linkers for antibody-drug conjugates.

N Ashman, JD Bargh, SJ Walsh, RD Greenwood, A Tiberghien, JS Carroll, DR Spring

– Chem Commun (Camb)

(2023)

59,

1841

(DOI: 10.1039/d2cc06677g)

A Chiral Amine Transfer Approach to the Photocatalytic Asymmetric Synthesis of α‑Trialkyl-α-tertiary Amines

GR Harris, AD Trowbridge, MJ Gaunt

– Organic Letters

(2023)

25,

861

(DOI: 10.1021/acs.orglett.2c04308)

Front Cover: Hybrid Androgen Receptor Inhibitors Outperform Enzalutamide and EPI‐001 in in vitro Models of Prostate Cancer Drug Resistance (ChemMedChem 2/2023)

RCB Nicolescu, ZR Maylin, FJ Pérez‐Areales, J Iegre, HS Pandha, M Asim, DR Spring

– ChemMedChem

(2023)

18,

(DOI: 10.1002/cmdc.202200703)

Multicomponent synthesis of α-chloro alkylboronic esters via visible-light-mediated dual catalysis

B Li, A Bunescu, MJ Gaunt

– Chem

(2023)

216

(DOI: 10.1016/j.chempr.2022.10.010)