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Recent Publications from the Synthesis Research Interest Group

Semi-syntheses of the 11-hydroxyrotenoids sumatrol and villosinol.
DA Russell, JJ Freudenreich, HL Stewart, AD Bond, HF Sore, DR Spring
– Org Biomol Chem
(2018)
16,
6395
(DOI: 10.1039/c8ob01919c)
C-H functionalisation of aldehydes using light generated, non-stabilised diazo compounds in flow.
P Dingwall, A Greb, LNS Crespin, R Labes, B Musio, J-S Poh, P Pasau, DC Blakemore, SV Ley
– Chemical communications (Cambridge, England)
(2018)
(DOI: 10.1039/c8cc06202a)
Ultrasound-induced gelation of a giant macrocycle.
D Núñez-Villanueva, MA Jinks, J Gómez Magenti, CA Hunter
– Chemical communications (Cambridge, England)
(2018)
(DOI: 10.1039/c8cc04742a)
Toward the total synthesis of patellazole B: synthesis of an advanced C1-C25 fragment corresponding to the macrocyclic skeleton.
AW Phillips, MJ Anketell, T Balan, NYS Lam, S Williams, I Paterson
– Org Biomol Chem
(2018)
(DOI: 10.1039/c8ob01621f)
Preparation of homoallylic amines via a three-component coupling process
X Ou, R Labes, C Battilocchio, SV Ley
– Org Biomol Chem
(2018)
(DOI: 10.1039/c8ob01831f)
H-Bonded Duplexes based on a Phenylacetylene Backbone.
JA Swain, G Iadevaia, CA Hunter
– Journal of the American Chemical Society
(2018)
140,
11526
(DOI: 10.1021/jacs.8b08087)
Coordination Cages Based on Bis(pyrazolylpyridine) Ligands: Structures, Dynamic Behavior, Guest Binding, and Catalysis.
MD Ward, CA Hunter, NH Williams
– Acc Chem Res
(2018)
(DOI: 10.1021/acs.accounts.8b00261)
Novel non-ATP competitive small molecules targeting the CK2 α/β interface.
P Brear, A North, J Iegre, K Hadje Georgiou, A Lubin, L Carro, W Green, HF Sore, M Hyvönen, DR Spring
– Bioorganic & medicinal chemistry
(2018)
26,
3016
(DOI: 10.1016/j.bmc.2018.05.011)
Integrated plug flow synthesis and crystallisation of pyrazinamide
CD Scott, R Labes, MJ Depardieu, C Battilocchio, MG Davidson, SV Ley, CC Wilson, K Robertson
– Reaction Chemistry & Engineering
(2018)
(DOI: 10.1039/C8RE00087E)
Using 2D Structural Alerts to Define Chemical Categories for Molecular Initiating Events
TEH Allen, JM Goodman, S Gutsell, PJ Russell
– Toxicological sciences : an official journal of the Society of Toxicology
(2018)
165,
213
(DOI: 10.1093/toxsci/kfy144)
A Convergent Continuous Multistep Process for the Preparation of C<inf>4</inf>-Oxime-Substituted Thiazoles
E Godineau, C Battilocchio, M Lehmann, SV Ley, R Labes, L Birnoschi, S Subramanian, CS Prasanna, A Gorde, M Kalbagh, V Khade, A Scherrer, AC O'Sullivan
– Organic Process Research and Development
(2018)
22,
955
(DOI: 10.1021/acs.oprd.8b00095)
Using Transition State Modeling To Predict Mutagenicity for Michael Acceptors.
TEH Allen, MN Grayson, JM Goodman, S Gutsell, PJ Russell
– J Chem Inf Model
(2018)
58,
1266
(DOI: 10.1021/acs.jcim.8b00130)
Engineering chemistry for the future of organic synthesis Preface
SV Ley
– Tetrahedron
(2018)
74,
3085
(DOI: 10.1016/j.tet.2018.05.046)
Professor Steven V Ley CBE FRS FMedSci
SV Ley
– Tetrahedron
(2018)
74,
3086
(DOI: 10.1016/j.tet.2018.05.047)
Highly diastereoselective boron and titanium mediated aldol reactions of a mannitol derived 2,3-butanediacetal ethyl ketone
M O'Brien, A Weber, G Hardy, SV Ley
– Tetrahedron
(2018)
74,
5319
(DOI: 10.1016/j.tet.2018.06.041)
Solvatomorphism of Reichardt's dye
SJ Pike, AD Bond, CA Hunter
– CrystEngComm
(2018)
20,
2912
(DOI: 10.1039/c8ce00480c)
Organic Photocatalysis for the Radical Couplings of Boronic Acid Derivatives in Batch and Flow
F Lima, L Grunenberg, HBA Rahman, R Labes, J Sedelmeier, SV Ley
– Chemical communications (Cambridge, England)
(2018)
54,
5606
(DOI: 10.1039/c8cc02169d)
A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin
G Menchon, AE Prota, D Lucena-Agell, P Bucher, R Jansen, H Irschik, R Müller, I Paterson, JF Díaz, K-H Altmann, MO Steinmetz
– Nature Communications
(2018)
9,
2106
(DOI: 10.1038/s41467-018-04535-8)
Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry.
DJ Ritson, C Battilocchio, SV Ley, JD Sutherland
– Nature Communications
(2018)
9,
1821
(DOI: 10.1038/s41467-018-04147-2)
Ion Pair-Directed C-H Activation on Flexible Ammonium Salts: Meta-Selective Borylation of Quaternized Phenethylamines and Phenylpropylamines
MT Mihai, HJ Davis, GR Genov, RJ Phipps
– ACS Catalysis
(2018)
8,
3764
(DOI: 10.1021/acscatal.8b00423)

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