Yusuf Hamied Department of Chemistry

Recent Publications from the Synthetic Chemistry Research Interest Group

An Alkali Amide Approach to Triphosphabenzenes
O Jones, A Bond, R Webster
Angewandte Chemie International Edition
(2026)
Design and synthesis of bioactive molecules
F Zhang, DR Spring
Beilstein Journal of Organic Chemistry
(2026)
22
(doi: 10.3762/bjoc.22.112)
An extragenic fix for a broken enzyme
V Mohan, E Labrini, CS Aksoy, V Behrends, LC Evangelista, DR Spring, M Welch
Microbiology (United Kingdom)
(2026)
172
(doi: 10.1099/mic.0.001760)
Catalytic atroposelective macrocyclization for constructing dominant rotors in peptides
L Zeng, Y Ou, T Yang, A Rowley, P Rukovanský, AD Bond, AK Yudin, DR Spring
Chem
(2026)
(doi: 10.1016/j.chempr.2026.103257)
A microfluidic fluorescence lifetime screening platform bridges in vitro and in vivo formats and enables discovery of Amyloid β aggregation inhibitors
F Hollfelder, S Collins, L van Vliet, GS Kaminski Schierle, DR Spring, M Janeček, NF Läubli, S Wagner Valladolid, C Poudel, A Fernandez-Villegas, T Deingruber, G Fusco, A De Simone, C Michel, CF Kaminski
Nature Communications
(2026)
Biphasic Solar Reforming of Lignin to Aromatics and CO for In Situ Carbonylation of Organics.
D Mittal, S Mitra, E Bonvin, DR Spring, SA Bonke, E Reisner
J Am Chem Soc
(2026)
148
(doi: 10.1021/jacs.6c10525)
Divinyl-s-tetrazine as a Minimal Linchpin for Peptide Stapling, Protein Disulfide Re-bridging and Click Functionalisation
T Yang, Y Cui, DK Wanic, L Zeng, MR Howarth, DR Spring
(2026)
(doi: 10.26434/chemrxiv.15007631/v1)
Frontispiece: Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
JL Venne, S Krajcovicova, G Davies, H Bolt, J Revell, DR Spring
Angewandte Chemie International Edition
(2026)
65
(doi: 10.1002/anie.2026-m2607093600)
Programmable remodelling of carbon-nitrogen connectivity in amines.
JD Robinson, F Richard, KA Ratkovich, JM Phelps, MJ Gaunt
Nature
(2026)
658
(doi: 10.1038/s41586-026-11009-1)
Frontispiece: Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
JL Venne, S Krajcovicova, G Davies, H Bolt, J Revell, DR Spring
Angewandte Chemie
(2026)
138
(doi: 10.1002/ange.2026-m2607093600)
Diarylethene-Containing Photoswitchable Analogues of Tubulysins-Design, Synthesis, Biological, and Structural Evaluation
A Iampolska, S Afonin, O Babii, M Park, J Estévez‐Gallego, MO Steinmetz, AE Prota, AS Ulrich, DR Spring, IV Komarov
European Journal of Organic Chemistry
(2026)
29
(doi: 10.1002/ejoc.70755)
StereoselectiveEpimerization of 1,3-Diols Using aChiral Hydrogen Atom Abstraction Catalyst
M Lemmerer, DC Emmet, ASK Lahdenperä, DJ Davies, A Dahiya, K Ermanis, RJ Phipps
Journal of the American Chemical Society
(2026)
148
(doi: 10.1021/jacs.6c10166)
Finding REMO: a sequencing method for recognition-encoded melamine oligomers.
B Iddon, PH Grab, JT Smith, ON Evans, A-L Cotîrlan, CA Hunter
Chemical science
(2026)
17
(doi: 10.1039/d6sc05680f)
Selective Inhibition of CK2: Emerging Strategies and Future Directions
AR Sokhal, S Krajcovicova, J Iegre, P Brear, C De Fusco, PA Glossop, D Cawkill, M Hyvönen, DR Spring
Journal of Medicinal Chemistry
(2026)
69
(doi: 10.1021/acs.jmedchem.6c00643)
Hybrid QM/ML approaches for the prediction of regioselectivity in Minisci C–H functionalisation reactions
SG Espley, M Šiaučiulis, N Palmer, JEH Day, JM Goodman, R Grainger, C Poelking
(2026)
(doi: 10.26434/chemrxiv.15006275/v1)
Recent advances in antibody-drug conjugates.
JD Sydenham, T Wharton, DR Spring
Current opinion in chemical biology
(2026)
94
(doi: 10.1016/j.cbpa.2026.102727)
Active Templating by Mechanochemistry.
ON Evans, AM Belenguer, CA Hunter
Org Lett
(2026)
28
(doi: 10.1021/acs.orglett.6c02540)
Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers
A-L Cotîrlan, CJ Anderson, NEJ Eyre, DO Soloviev, B Iddon, F Balduzzi, CA Hunter
Journal of the American Chemical Society
(2026)
148
(doi: 10.1021/jacs.6c07701)
Optimization of a Resolution Process Allowing Access to Both Enantiomers of the Versatile Chiral Phosphine Ligand sSPhos on Scale
H Sharif, TD Svejstrup, S Karlsson, RJ Phipps
Organic Process Research & Development
(2026)
30
(doi: 10.1021/acs.oprd.6c00142)
An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically‐Directed Palladium Catalysis
M Kadarauch, PT Jirsch, HE Diepers, H Sharif, RJ Phipps
Angewandte Chemie
(2026)
138
(doi: 10.1002/ange.8602143)
An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically‐Directed Palladium Catalysis
M Kadarauch, PT Jirsch, HE Diepers, H Sharif, RJ Phipps
Angewandte Chemie International Edition
(2026)
65
(doi: 10.1002/anie.8602143)
Regio- and Enantioselective Alkoxycarbonylation of Unactivated Terminal Alkenes under Palladium-Bromide-Monophosphine Catalysis
M Sigrist, K Das, G Kurpik, W Tian, J Huang, A Covas, AD Bond, W Tang, P Dydio
Journal of the American Chemical Society
(2026)
148
(doi: 10.1021/jacs.6c10237)
Peptide Marriages: Modular Assembly of Multi-Agonist Therapeutics.
KA Kostadinova, JL Venne, S Krajcovicova, J Dodgson, WFJ Hogendorf, TE Nielsen, D Hymel, H Bolt, A Collinson, J Day, J Revell, DR Spring
Chemistry A European Journal
(2026)
32
(doi: 10.1002/chem.71280)
Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
JL Venne, S Krajcovicova, G Davies, H Bolt, J Revell, DR Spring
Angewandte Chemie
(2026)
138
(doi: 10.1002/ange.9595531)
Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
JL Venne, S Krajcovicova, G Davies, H Bolt, J Revell, DR Spring
Angewandte Chemie International Edition
(2026)
65
(doi: 10.1002/anie.9595531)
Yusuf Hamied Department of Chemistry
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