Yusuf Hamied Department of Chemistry

Recent Publications from the Synthetic Chemistry Research Interest Group

Advancing Structure Elucidation with a Flexible Multi‐Spectral AI Model
M Priessner, RJ Lewis, I Lemurell, MJ Johansson, J Goodman, JP Janet, A Tomberg
Angewandte Chemie International Edition
(2025)
(doi: 10.1002/ange.202517611)
Towards a glutathione-cleavable azobenzene linker for antibody-drug conjugates.
M Kapun, R Patel, M Park, FJ Pérez-Areales, KA Kostadinova, T Wharton, JS Carroll, DR Spring
Chemical Communications
(2025)
(doi: 10.1039/d5cc05824d)
Recent progress towards catalytic asymmetric construction of inherently chiral scaffolds.
K Zhu, DR Spring, B-F Shi, F Zhang
Chem Soc Rev
(2025)
(doi: 10.1039/d5cs00235d)
Exploiting the Cryptic αD Pocket of Casein Kinase 2α (CK2α) to Deliver Highly Potent and Selective Type 1 Inhibitors.
PA Glossop, P Brear, S Wright, N Flanagan, MS Glossop, CAL Lane, RP Butt, DR Spring, M Hyvönen, D Cawkill
J Med Chem
(2025)
68
(doi: 10.1021/acs.jmedchem.5c01807)
Towards automatically verifying chemical structures: the powerful combination of 1H NMR and IR spectroscopy.
J Goodman, R Lewis, JB Rowlands, L Jonsson, P Howe, W Czechtizky, T Leek
Chemical Science
(2025)
16
(doi: 10.1039/D5SC06866E)
Continuous Flow Techniques in the Total Synthesis of Jaspine B: Part II.
M Gurský, D Trnovcová, P Lopatka, M Markovič, P Koóš, SV Ley, T Gracza
The Journal of organic chemistry
(2025)
90
(doi: 10.1021/acs.joc.5c01799)
β-Lactamase cleavable antimicrobial peptide-drug conjugates
T Deingruber, JS Gaynord, BH Gan, KA Kostadinova, TJ O'Brien, YS Tan, JS Parker, TA Hunt, JS Carroll, M Welch, DR Spring
Chemical science
(2025)
16
(doi: 10.1039/d5sc06369h)
The development of sulfonated terpyridine ligands for control of regioselectivity in palladium-catalysed fluorination of anilides
J Dolezel, RJ Phipps
Chem Sci
(2025)
16
(doi: 10.1039/d5sc05799j)
Development of D-box peptides to inhibit the anaphase-promoting complex/cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, EJ Fisher, M Zacharopoulou, F Ferrer, D Barford, DR Spring, C Lindon, C Phillips, LS Itzhaki
eLife
(2025)
14
(doi: 10.7554/elife.104238)
A Dynamic Silver(I) Nanocluster Holds Together a 3 × 3 Self-Assembled Grid.
AW Heard, L Pesce, PT Gierth, S Adorinni, TK Ronson, B Rossi, JD Thoburn, T Deingruber, M Welch, DR Spring, S Marchesan, GM Pavan, JR Nitschke
J Am Chem Soc
(2025)
147
(doi: 10.1021/jacs.5c07271)
Selective endo-Cyclic α‑Functionalization of Saturated N‑Alkyl Piperidines
RC Phillips, JCK Chu, AA Rafaniello, MJ Gaunt
Journal of Organic Chemistry
(2025)
90
(doi: 10.1021/acs.joc.5c01742)
Chirality-Assisted Self-Assembly of Low-Symmetry Noncovalent Capsules with Quantitative Diastereoisomeric Selection
G Markiewicz, X Qiu, G Avci, EH Wolpert, KE Jelfs, JKM Sanders, AR Stefankiewicz
Journal of the American Chemical Society
(2025)
147
(doi: 10.1021/jacs.5c10523)
Template-directed ligation of recognition-encoded melamine oligomers
LA Beale, JT Smith, CJ Anderson, ON Evans, CA Hunter
Chem Sci
(2025)
16
(doi: 10.1039/d5sc05650k)
Allylic Amination of Alkenyl Alcohols: Simultaneous Control of Chemoselectivity and Enantioselectivity in Nitrene Transfer Using Ion-Paired Catalysts.
HK Adams, A Fanourakis, A Dahiya, I Băltăreţu, RJ Phipps
ACS Catal
(2025)
15
(doi: 10.1021/acscatal.5c04140)
Structural and gas uptake studies on iron(II) β-diketiminate metallo-macrocycles
AN Barrett, L Webster, D Gasperini, R Castaing, MF Mahon, RL Webster
Organometallics
(2025)
44
(doi: 10.1021/acs.organomet.5c00208)
Structural and Gas Uptake Studies on Iron(II) β-Diketiminate Metallomacrocycles
AN Barrett, L Webster, D Gasperini, R Castaing, MF Mahon, RL Webster
Organometallics
(2025)
44
(doi: 10.1021/acs.organomet.5c00208)
Intercepting Methanimine for the Synthesis of Piperidine-Based N-Heterocycles in an Aqueous Medium
E Pocock, M Diefenbach, TM Hood, M Nunn, V Krewald, SE Lewis, RL Webster
The Journal of Organic Chemistry
(2025)
90
(doi: 10.1021/acs.joc.5c01213)
Supramolecular Assembly Properties of a Mixed-Sequence Recognition-Encoded Melamine Oligomer
M Dhiman, JT Smith, CA Hunter
Organic & biomolecular chemistry
(2025)
23
(doi: 10.1039/d5ob00769k)
Enantioselective Formal Synthesis of (−)-Aflatoxin B2 Enabled by Pd-Catalyzed Carboetherification of 2,3-Dihydrofuran
M Kadarauch, RJ Phipps
Organic Letters
(2025)
27
(doi: 10.1021/acs.orglett.5c02618)
Detecting alpha-synuclein aggregates with small molecules on single-molecule array.
JYL Lam, TS Chisholm, H Almahli, EA English, Z Xia, Y Wu, MR Cheetham, CA Hunter, D Klenerman
Chemical Science
(2025)
16
(doi: 10.1039/d4sc07649d)
Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
Angewandte Chemie International Edition
(2025)
64
(doi: 10.1002/anie.202507532)
Asymmetric Aziridination of Allylic Carbamates Using Ion‐Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
Angewandte Chemie
(2025)
137
(doi: 10.1002/ange.202507532)
Asymmetric Aziridination of Allylic Carbamates Using Ion-Paired Rhodium Complexes and Extrapolation to C─H Amination of Phenethyl Carbamates
AR Lit, S Takano, C Zachau, I Băltărețu, RJ Phipps
Angew Chem Int Ed Engl
(2025)
64
(doi: 10.1002/anie.202507532)
Prediction of solution phase association constants by mapping contact points in intermolecular complexes.
KJ Zator, CA Hunter
Physical Chemistry, Chemical Physics - PCCP
(2025)
27
(doi: 10.1039/d5cp00398a)
Dehomologative C–C Borylation of Aldehydes and Alcohols via a Rh-Catalyzed Dehydroformylation–Borylation Relay
K Das, N Kuźnik, P Dydio
J Am Chem Soc
(2025)
147
(doi: 10.1021/jacs.5c02181)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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