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Recent Publications from the Synthesis Research Interest Group

Exploiting attractive non-covalent interactions for the enantioselective catalysis of reactions involving radical intermediates.
RSJ Proctor, AC Colgan, RJ Phipps
– Nat Chem
(2020)
12,
1
(DOI: 10.1038/s41557-020-00561-6)
Living with our machines: Towards a more sustainable future
SV Ley, Y Chen, DE Fitzpatrick, OS May
– Current Opinion in Green and Sustainable Chemistry
(2020)
25,
100353
(DOI: 10.1016/j.cogsc.2020.100353)
Total Synthesis of the Actinoallolides and a Designed Photoaffinity Probe for Target Identification
MJ Anketell, TM Sharrock, I Paterson
– Organic & Biomolecular Chemistry
(2020)
(DOI: 10.1039/d0ob01831g)
Recent Developments in Enantioselective Transition Metal Catalysis Featuring Attractive Noncovalent Interactions between Ligand and Substrate.
A Fanourakis, PJ Docherty, P Chuentragool, RJ Phipps
– ACS catalysis
(2020)
10,
10672
(DOI: 10.1021/acscatal.0c02957)
Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics
J Charoenpattarapreeda, SJ Walsh, JS Carroll, DR Spring
– Angewandte Chemie
(2020)
ange.202010090
(DOI: 10.1002/ange.202010090)
Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics
J Charoenpattarapreeda, SJ Walsh, JS Carroll, DR Spring
– Angew Chem Int Ed Engl
(2020)
anie.202010090
(DOI: 10.1002/anie.202010090)
Template Effects of Vesicles in Dynamic Covalent Chemistry
C Bravin, CA Hunter
– Chemical Science
(2020)
11,
9122
(DOI: 10.1039/d0sc03185b)
Synthesis and Reactivity of Stable Alkyl-Pd(IV) Complexes Relevant to Monodentate N-Directed C(sp3)–H Functionalization Processes
WG Whitehurst, MJ Gaunt
– Journal of the American Chemical Society
(2020)
142,
14169
(DOI: 10.1021/jacs.0c04732)
Photoredox generation of sulfonyl radicals and coupling with electron deficient olefins
Y Chen, N McNamara, O May, T Pillaiyar, DC Blakemore, SV Ley
– Organic letters
(2020)
22,
5746
(DOI: 10.1021/acs.orglett.0c01730)
5′‐Methyl[2,2′‐bipyridine]‐5‐methanesulfonic Acid, Tetrabutylammonium Salt
GR Genov, JL Douthwaite, RJ Phipps
(2020)
1
(DOI: 10.1002/047084289x.rn02345)
Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A.
IE Ndukwe, X Wang, NYS Lam, K Ermanis, KL Alexander, MJ Bertin, GE Martin, G Muir, I Paterson, R Britton, JM Goodman, EJN Helfrich, J Piel, WH Gerwick, RT Williamson
– Chemical communications (Cambridge, England)
(2020)
56,
7565
(DOI: 10.1039/d0cc03055d)
C(sp 3 )–H arylation to construct all- syn cyclobutane-based heterobicyclic systems: a novel fragment collection
TJ Osberger, SL Kidd, TA King, DR Spring
– Chem Commun (Camb)
(2020)
56,
7423
(DOI: 10.1039/d0cc03237a)
Efficient and selective antibody modification with functionalised divinyltriazines
AJ Counsell, SJ Walsh, NS Robertson, HF Sore, DR Spring
– Organic & biomolecular chemistry
(2020)
18,
4739
(DOI: 10.1039/d0ob01002b)
Neural Network Activation Similarity: A New Measure to Assist Decision Making in Chemical Toxicology
TEH Allen, AJ Wedlake, E Gelžinytė, C Gong, JM Goodman, S Gutsell, PJ Russell
– Chemical Science
(2020)
11,
7335
(DOI: 10.1039/d0sc01637c)
Supramolecular catalysis by recognition-encoded oligomers: Discovery of a synthetic imine polymerase
L Gabrielli, CA Hunter
– Chemical Science
(2020)
11,
7408
(DOI: 10.1039/d0sc02234a)
In silico rationalisation of selectivity and reactivity in Pd-catalysed C–H activation reactions
L Cao, M Kabeshov, SV Ley, AA Lapkin
– Beilstein J Org Chem
(2020)
16,
1465
(DOI: 10.3762/bjoc.16.122)
In Silico Guidance for in Vitro Androgen and Glucocorticoid Receptor ToxCast Assays
TEH Allen, MD Nelms, SW Edwards, JM Goodman, S Gutsell, PJ Russell
– Environmental Science and Technology
(2020)
54,
7461
(DOI: 10.1021/acs.est.0c01105)
Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A
I Paterson, IE Ndukwe, X Wang, NYS Lam, K Ermanis, KL Alexander, MJ Bertin, GE Martin, G Muir, R Britton, JM Goodman, EJN Helfrich, J Piel, WH Gerwick, RT Williamson
– Chemical Communications
(2020)
(DOI: 10.1039/d0cc03055d)
Adventures in drugging undruggable targets
DR Spring
– JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
(2020)
63,
362
General dual functionalisation of biomacromolecules via a cysteine bridging strategy
SJ Walsh, J Iegre, H Seki, JD Bargh, HF Sore, JS Parker, JS Carroll, DR Spring
– Organic and Biomolecular Chemistry
(2020)
18,
4224
(DOI: 10.1039/d0ob00907e)

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