Yusuf Hamied Department of Chemistry

Recent Publications from the Synthetic Chemistry Research Interest Group

An Alkali Amide Approach to Triphosphabenzenes.
OJ Jones, AD Bond, RL Webster
Angew Chem Int Ed Engl
(2026)
(doi: 10.1002/anie.5634995)
An Alkali Amide Approach to Triphosphabenzenes
OJ Jones, AD Bond, RL Webster
Angewandte Chemie
(2026)
(doi: 10.1002/ange.5634995)
Dissecting the Influence of Molecular Charge on Hydrophobicity.
B Iddon, C Hunter
Journal of the American Chemical Society
(2026)
Design and synthesis of bioactive molecules.
F Zhang, DR Spring
Beilstein Journal of Organic Chemistry
(2026)
22
(doi: 10.3762/bjoc.22.112)
An extragenic fix for a broken enzyme.
V Mohan, E Labrini, CS Aksoy, V Behrends, LC Evangelista, DR Spring, M Welch
Microbiology (Reading)
(2026)
172
(doi: 10.1099/mic.0.001760)
Catalytic atroposelective macrocyclization for constructing dominant rotors in peptides
L Zeng, Y Ou, T Yang, A Rowley, P Rukovanský, AD Bond, AK Yudin, DR Spring
Chem
(2026)
(doi: 10.1016/j.chempr.2026.103257)
A microfluidic fluorescence lifetime screening platform bridges in vitro and in vivo formats and enables discovery of Amyloid β aggregation inhibitors
F Hollfelder, S Collins, L van Vliet, GS Kaminski Schierle, DR Spring, M Janeček, NF Läubli, S Wagner Valladolid, C Poudel, A Fernandez-Villegas, T Deingruber, G Fusco, A De Simone, C Michel, CF Kaminski
Nature Communications
(2026)
Biphasic Solar Reforming of Lignin to Aromatics and CO for In Situ Carbonylation of Organics.
D Mittal, S Mitra, E Bonvin, DR Spring, SA Bonke, E Reisner
Journal of the American Chemical Society
(2026)
148
(doi: 10.1021/jacs.6c10525)
Divinyl-s-tetrazine as a Minimal Linchpin for Peptide Stapling, Protein Disulfide Re-bridging and Click Functionalisation
T Yang, Y Cui, DK Wanic, L Zeng, MR Howarth, DR Spring
(2026)
(doi: 10.26434/chemrxiv.15007631/v1)
Frontispiece: Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
JL Venne, S Krajcovicova, G Davies, H Bolt, J Revell, DR Spring
Angewandte Chemie
(2026)
138
(doi: 10.1002/ange.2026-m2607093600)
Programmable remodelling of carbon-nitrogen connectivity in amines
JD Robinson, F Richard, KA Ratkovich, JM Phelps, MJ Gaunt
Nature
(2026)
658
(doi: 10.1038/s41586-026-11009-1)
Frontispiece: Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
JL Venne, S Krajcovicova, G Davies, H Bolt, J Revell, DR Spring
Angewandte Chemie International Edition
(2026)
65
(doi: 10.1002/anie.2026-m2607093600)
Diarylethene‐Containing Photoswitchable Analogues of Tubulysins—Design, Synthesis, Biological, and Structural Evaluation
A Iampolska, S Afonin, O Babii, M Park, J Estévez‐Gallego, MO Steinmetz, AE Prota, AS Ulrich, DR Spring, IV Komarov
European Journal of Organic Chemistry
(2026)
29
(doi: 10.1002/ejoc.70755)
Stereoselective Epimerization of 1,3-Diols Using a Chiral Hydrogen Atom Abstraction Catalyst.
M Lemmerer, DC Emmet, ASK Lahdenperä, DJ Davies, A Dahiya, K Ermanis, RJ Phipps
J Am Chem Soc
(2026)
148
(doi: 10.1021/jacs.6c10166)
Finding REMO: A Sequencing Method for Recognition-Encoded Melamine Oligomers
B Iddon, PH Grab, JT Smith, ON Evans, A-L Cotîrlan, CA Hunter
Chem Sci
(2026)
17
(doi: 10.1039/d6sc05680f)
Selective Inhibitionof CK2: Emerging Strategies andFuture Directions
AR Sokhal, S Krajcovicova, J Iegre, P Brear, C De Fusco, PA Glossop, D Cawkill, M Hyvönen, DR Spring
Journal of Medicinal Chemistry
(2026)
69
(doi: 10.1021/acs.jmedchem.6c00643)
Hybrid QM/ML approaches for the prediction of regioselectivity in Minisci C–H functionalisation reactions
SG Espley, M Šiaučiulis, N Palmer, JEH Day, JM Goodman, R Grainger, C Poelking
(2026)
(doi: 10.26434/chemrxiv.15006275/v1)
Recent advances in antibody–drug conjugates
JD Sydenham, T Wharton, DR Spring
Current Opinion in Chemical Biology
(2026)
94
(doi: 10.1016/j.cbpa.2026.102727)
Active Templating by Mechanochemistry
ON Evans, AM Belenguer, CA Hunter
Organic Letters
(2026)
28
(doi: 10.1021/acs.orglett.6c02540)
Sequence-Dependent Folding of Recognition-Encoded Melamine Oligomers
A-L Cotîrlan, CJ Anderson, NEJ Eyre, DO Soloviev, B Iddon, F Balduzzi, CA Hunter
Journal of the American Chemical Society
(2026)
148
(doi: 10.1021/jacs.6c07701)
Optimization of a Resolution Process Allowing Access to Both Enan-tiomers of the Versatile Chiral Phosphine Ligand sSPhos on Scale
H Sharif, TD Svejstrup, S Karlsson, RJ Phipps
Organic Process Research & Development
(2026)
30
(doi: 10.1021/acs.oprd.6c00142)
An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically‐Directed Palladium Catalysis
M Kadarauch, PT Jirsch, HE Diepers, H Sharif, RJ Phipps
Angewandte Chemie
(2026)
138
(doi: 10.1002/ange.8602143)
An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically‐Directed Palladium Catalysis
M Kadarauch, PT Jirsch, HE Diepers, H Sharif, RJ Phipps
Angewandte Chemie International Edition
(2026)
65
(doi: 10.1002/anie.8602143)
Regio- and Enantioselective Alkoxycarbonylation of Unactivated Terminal Alkenes under Palladium-Bromide-Monophosphine Catalysis.
M Sigrist, K Das, G Kurpik, W Tian, J Huang, A Covas, AD Bond, W Tang, P Dydio
Journal of the American Chemical Society
(2026)
148
(doi: 10.1021/jacs.6c10237)
Peptide Marriages: Modular Assembly of Multi‐Agonist Therapeutics
KA Kostadinova, JL Venne, S Krajcovicova, J Dodgson, WFJ Hogendorf, TE Nielsen, D Hymel, H Bolt, A Collinson, J Day, J Revell, DR Spring
Chemistry - A European Journal
(2026)
32
(doi: 10.1002/chem.71280)
Yusuf Hamied Department of Chemistry
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