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Yusuf Hamied Department of Chemistry

 

Recent Publications from the Synthesis Research Interest Group

Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, EJ Fisher, M Zacharopoulou, F Ferrer, D Barford, D Spring, C Lindon, C Phillips, LS Itzhaki
(2025)
(DOI: 10.7554/elife.104238)
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, EJ Fisher, M Zacharopoulou, F Ferrer, D Barford, D Spring, C Lindon, C Phillips, LS Itzhaki
(2025)
(DOI: 10.7554/elife.104238.2)
The supramolecular chemistry of monodisperse 1,3,5-triazine oligomers.
L Escobar, CA Hunter
– Organic & biomolecular chemistry
(2025)
23,
3520
(DOI: 10.1039/d5ob00321k)
Solvation Energies from Atomic Surface Site Interaction Points
E Gross, MD Driver, A Saif, ON Evans, CA Hunter
– Physical chemistry chemical physics : PCCP
(2025)
(DOI: 10.1039/d5cp00635j)
Quantification of the effects of n-π* interactions on the H-bonding properties of amide groups.
FE Hanna, AD Bond, CA Hunter
– Chem Sci
(2025)
(DOI: 10.1039/d4sc08331h)
Relationship between Interaction Geometry and Cooperativity Measured in H-Bonded Networks of Hydroxyl Groups
L Trevisan, AD Bond, CA Hunter
– Chemical Science
(2025)
(DOI: 10.1039/d5sc00784d)
Straightforward, Scalable, Solution-Phase Synthesis of Peptide Bonds in Flow.
ZE Wilson, E Lopez, NJ Flodén, C Watkins, G Bianchini, SV Ley
– Journal of Flow Chemistry
(2025)
1
(DOI: 10.1007/s41981-025-00347-2)
Pseudomonas aeruginosa acyl-CoA dehydrogenases and structure-guided inversion of their substrate specificity.
M Wang, P Medarametla, T Kronenberger, T Deingruber, P Brear, W Figueroa, P-M Ho, T Krueger, JC Pearce, A Poso, JG Wakefield, DR Spring, M Welch
– Nature Communications
(2025)
16,
2334
(DOI: 10.1038/s41467-025-57532-z)
Methods for the Generation of Single‐Payload Antibody‐Drug Conjugates
T Wharton, DR Spring
– ChemMedChem
(2025)
e202500132
(DOI: 10.1002/cmdc.202500132)
Cooperativity in the assembly of H-bonded duplexes of synthetic recognition-encoded melamine oligomers.
M Dhiman, L Escobar, JT Smith, CA Hunter
– Chemical Science
(2025)
16,
5995
(DOI: 10.1039/d4sc08591d)
Pseudomonas aeruginosa PfpI is a methylglyoxalase.
L Grimm, A Wijaya, I Askenasy, RR Nazeer, H Seki, PD Brear, W Figueroa, DR Spring, M Welch
– J Biol Chem
(2025)
301,
108374
(DOI: 10.1016/j.jbc.2025.108374)
Design Approaches That Utilize Ionic Interactions to Control Selectivity in Transition Metal Catalysis
HK Adams, M Kadarauch, NJ Hodson, AR Lit, RJ Phipps
– Chemical Reviews
(2025)
125,
2846
(DOI: 10.1021/acs.chemrev.4c00849)
The 2-methylcitrate cycle and the glyoxylate shunt in Pseudomonas aeruginosa are linked through enzymatic redundancy
AJ Wijaya, SK Dolan, M Kohlstedt, L Gläser, P Brear, S Geddis, C Wittmann, DR Spring, M Welch
– The Journal of biological chemistry
(2025)
301,
108355
(DOI: 10.1016/j.jbc.2025.108355)
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, E McCall, M Zacharopoulou, F Ferrer, D Barford, D Spring, C Lindon, C Phillips, LS Itzhaki
(2025)
(DOI: 10.7554/elife.104238.1)
Advances in the Release of Amide-Containing Molecules
T Wharton, DR Spring
– Chemistry
(2025)
31,
e202404413
(DOI: 10.1002/chem.202404413)
Covalent Template-Directed Synthesis: A Powerful Tool for the Construction of Complex Molecules
P Bolgar, M Dhiman, D Núñez-Villanueva, CA Hunter
– Chemical Reviews
(2025)
125,
1629
(DOI: 10.1021/acs.chemrev.4c00505)
Sequence-selective pulldown of recognition-encoded melamine oligomers using covalent capture on a solid support.
L Escobar, D Sun, M Dhiman, CA Hunter
– Chem Commun (Camb)
(2025)
61,
504
(DOI: 10.1039/d4cc06018k)
The supramolecular chemistry of monodisperse 1,3,5-triazine oligomers
L Escobar, CA Hunter
– Organic & Biomolecular Chemistry
(2025)
23,
3520
(DOI: 10.1039/d5ob00321k)
Solvation energies from atomic surface site interaction points
E Gross, MD Driver, A Saif, ON Evans, CA Hunter
– Physical Chemistry Chemical Physics
(2025)
(DOI: 10.1039/d5cp00635j)
Relationship between interaction geometry and cooperativity measured in H-bonded networks of hydroxyl groups
L Trevisan, AD Bond, CA Hunter
– Chemical Science
(2025)
(DOI: 10.1039/d5sc00784d)

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