skip to content
Home

Department of Chemistry

 

Recent Publications from the Synthesis Research Interest Group

Electrostatically-Directed Pd-Catalysis in Combination with C-H Activation: Site-Selective Coupling of Remote Chlorides with Fluoroarenes and Fluoroheteroarenes
WA Golding, RJ Phipps
– Chemical Science
(2020)
11,
3022
(DOI: 10.1039/d0sc00105h)
Enantioselective remote C-H activation directed by a chiral cation
GR Genov, JL Douthwaite, ASK Lahdenperä, DC Gibson, RJ Phipps
– Science
(2020)
367,
1246
(DOI: 10.1126/science.aay9187)
New Strategies for the Transition-Metal Catalyzed Synthesis of Aliphatic Amines.
A Trowbridge, SM Walton, MJ Gaunt
– Chemical Reviews
(2020)
120,
2613
(DOI: 10.1021/acs.chemrev.9b00462)
Hetero Co-Encapsulation within a Supramolecular Cage. Moving Away from the Statistical Distribution of Different Guests.
C Bravin, G Licini, C Zonta, CA Hunter
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2020)
chem.202000574
(DOI: 10.1002/chem.202000574)
Charge-assisted phosph( v )azane anion receptors
AJ Plajer, S Lee, AD Bond, JM Goodman, DS Wright
– Dalton Transactions
(2020)
49,
3403
(DOI: 10.1039/d0dt00489h)
Quantification of cooperativity in the self-assembly of H-bonded rosettes.
P Motloch, CA Hunter
– Organic and Biomolecular Chemistry
(2020)
18,
1602
(DOI: 10.1039/d0ob00068j)
Fsp 3 -rich and diverse fragments inspired by natural products as a collection to enhance fragment-based drug discovery
AR Hanby, NS Troelsen, TJ Osberger, SL Kidd, KT Mortensen, DR Spring
– Chem Commun (Camb)
(2020)
56,
2280
(DOI: 10.1039/c9cc09796a)
Rapid Syntheses of (−)-FR901483 and (+)-TAN1251C Enabled by Complexity-Generating Photocatalytic Olefin Hydroaminoalkylation
D Reich, A Trowbridge, MJ Gaunt
– Angewandte Chemie - International Edition
(2020)
59,
2256
(DOI: 10.1002/anie.201912010)
Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents.
TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, JS Parker, DR Spring, I Paterson
– Chem Commun (Camb)
(2020)
56,
1529
(DOI: 10.1039/c9cc09050a)
A Unified Total Synthesis of the Actinoallolides, a Family of Potent Anti‐Trypanosomal Macrolides
MJ Anketell, TM Sharrock, I Paterson
– Angewandte Chemie
(2020)
132,
1588
(DOI: 10.1002/ange.201914042)
A tutored discourse on microcontrollers, single board computers and their applications to monitor and control chemical reactions
DE Fitzpatrick, M O'Brien, SV Ley
– Reaction Chemistry & Engineering
(2020)
5,
201
(DOI: 10.1039/c9re00407f)
Sulfatase-cleavable linkers for antibody-drug conjugates
JD Bargh, SJ Walsh, A Isidro-Llobet, S Omarjee, JS Carroll, DR Spring
– Chemical Science
(2020)
11,
2375
(DOI: 10.1039/c9sc06410a)
Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction.
K Sharma, AV Strizhak, E Fowler, W Xu, B Chappell, HF Sore, WRJD Galloway, MN Grayson, YH Lau, LS Itzhaki, DR Spring
– ACS omega
(2020)
5,
1157
(DOI: 10.1021/acsomega.9b03459)
Editorial 2020: Changing publishing and academic culture
JKM Sanders
– Royal Society Open Science
(2020)
7,
192197
(DOI: 10.1098/rsos.192197)
Development of a Novel Cell-Permeable Protein–Protein Interaction Inhibitor for the Polo-box Domain of Polo-like Kinase 1
DJ Huggins, BS Hardwick, P Sharma, A Emery, L Laraia, F Zhang, AJ Narvaez, M Roberts-Thomson, AT Crooks, RG Boyle, R Boyce, DW Walker, N Mateu, GJ McKenzie, DR Spring, AR Venkitaraman
– ACS Omega
(2020)
5,
822
(DOI: 10.1021/acsomega.9b03626)
A Practical Method for Continuous Production of sp3‐Rich Compounds from (Hetero)Aryl Halides and Redox‐Active Esters
E Watanabe, Y Chen, O May, SV Ley
– Chemistry - A European Journal
(2020)
26,
186
(DOI: 10.1002/chem.201905048)
ThX – a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
– Chemical Science
(2020)
(DOI: 10.1039/c9sc04730a)
Towards the Total Synthesis of Hemicalide: Synthesis of the C27-C46 Region
TP Stockdale, BY Han, NYS Lam, JM Goodman, I Paterson
– MARINE DRUGS
(2020)
18,
Catalytic C(sp(3))-H bond activation in tertiary alkylamines
J Rodrigalvarez, M Nappi, H Azuma, NJ Flodén, ME Burns, MJ Gaunt
– Nature Chemistry
(2020)
12,
76
(DOI: 10.1038/s41557-019-0393-8)
Structural Alerts and Random Forest Models in a Consensus Approach for Receptor Binding Molecular Initiating Events
AJ Wedlake, M Folia, S Piechota, TEH Allen, JM Goodman, S Gutsell, PJ Russell
– Chemical Research in Toxicology
(2020)
33,
388
(DOI: 10.1021/acs.chemrestox.9b00325)

    Study at Cambridge

    About the University

    Research at Cambridge