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Yusuf Hamied Department of Chemistry

The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril ends
MM Schneider, S Gautam, TW Herling, E Andrzejewska, G Krainer, AM Miller, VA Trinkaus, QAE Peter, FS Ruggeri, M Vendruscolo, A Bracher, CM Dobson, FU Hartl, TPJ Knowles
– Nature communications
Intermolecular reorganisation of single-component condensates during ageing promotes multiphase architectures
A Garaizar, J Espinosa, J Joseph, G Krainer, Y Shen, TPJ Knowles, R Collepardo-Guevara
Accelerating Reaction Rates of Biomolecules by Using Shear Stress in Artificial Capillary Systems
TA Hakala, EV Yates, PK Challa, Z Toprakcioglu, K Nadendla, D Matak-Vinkovic, CM Dobson, R Martínez, F Corzana, TPJ Knowles, GJL Bernardes
– Journal of the American Chemical Society
Mechanochemical Synthesis and Physicochemical Characterization of Previously Unreported Praziquantel Solvates with 2-Pyrrolidone and Acetic Acid
D Zanolla, L Gigli, D Hasa, MR Chierotti, M Arhangelskis, N Demitri, W Jones, D Voinovich, B Perissutti
– Pharmaceutics
New Frontiers for Machine Learning in Protein Science.
AS Morgunov, KL Saar, M Vendruscolo, TPJ Knowles
– Journal of Molecular Biology
Sequential storage and release of microdroplets
Z Toprakcioglu, TPJ Knowles
– Microsystems & Nanoengineering
Mechanism of Secondary Nucleation at the Single Fibril Level from Direct Observations of Aβ42 Aggregation.
MR Zimmermann, SC Bera, G Meisl, S Dasadhikari, S Ghosh, S Linse, K Garai, TPJ Knowles
– Journal of the American Chemical Society
A Platform for Site-Specific DNA-Antibody Bioconjugation by Using Benzoylacrylic-labelled Oligonucleotides.
J Konč, L Brown, DR Whiten, Y Zuo, P Ravn, D Klenerman, GJL Bernardes
– Angew Chem Int Ed Engl
ChemDataExtractor 2.0: Autopopulated Ontologies for Materials Science.
J Mavračić, CJ Court, T Isazawa, SR Elliott, JM Cole
– Journal of Chemical Information and Modeling
Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling
KY Chen, E Jenkins, M Körbel, A Ponjavic, AH Lippert, AM Santos, N Ashman, C O'Brien-Ball, J McBride, D Klenerman, SJ Davis
– Proc Natl Acad Sci U S A
Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses
F Geiger, J Acker, G Papa, X Wang, WE Arter, KL Saar, NA Erkamp, R Qi, JP Bravo, S Strauss, G Krainer, OR Burrone, R Jungmann, TP Knowles, H Engelke, A Borodavka
– The EMBO journal
The binding of the small heat-shock protein alpha B-crystallin to fibrils of alpha-synuclein is driven by entropic forces
T Scheidt, JA Carozza, CC Kolbe, FA Aprile, O Tkachenko, MMJ Bellaiche, G Meisl, QAE Peter, TW Herling, S Ness, M Castellana-Cruz, JLP Benesch, M Vendruscolo, CM Dobson, P Arosio, TPJ Knowles
– Proc Natl Acad Sci U S A
Deformable and Robust Core-Shell Protein Microcapsules Templated by Liquid-Liquid Phase-Separated Microdroplets
Y Xu, Y Shen, TCT Michaels, KN Baumann, D Vigolo, Q Peter, Y Lu, KL Saar, D Vella, H Zhu, B Li, H Yang, APM Guttenplan, M Rodriguez-Garcia, D Klenerman, TPJ Knowles
– Advanced Materials Interfaces
Impacts of Hydroperoxymethyl Thioformate on the Global Marine Sulfur Budget
MAH Khan, TJ Bannan, R Holland, DE Shallcross, AT Archibald, E Matthews, A Back, J Allan, H Coe, P Artaxo, CJ Percival
– ACS Earth and Space Chemistry
Single-route delaminated clay composites for efficient visible-light photo-mineralization of antibiotic-resistant bacteria and associated genes in water
CG Ugwuja, D Olorunnisola, A Ogunlaja, OO Adelowo, A Taubert, GA Kolawole, OD Olukanni, JN Uwanibe, AT Kayode, P Hesemann, D Fatta-Kassinos, TAM Msagati, OA Folarin, SM Clarke, EI Unuabonah
– Applied Catalysis B Environmental
The Independent Volcanic Eruption Source Parameter Archive (IVESPA, version 1.0): A new observational database to support explosive eruptive column model validation and development
TJ Aubry, S Engwell, C Bonadonna, G Carazzo, S Scollo, AR Van Eaton, IA Taylor, D Jessop, J Eychenne, M Gouhier, LG Mastin, KL Wallace, S Biass, M Bursik, RG Grainger, AM Jellinek, A Schmidt
– Journal of Volcanology and Geothermal Research
A fast, low-energy multi-state phase-change artificial synapse based on uniform partial-state transitions
SX Go, TH Lee, SR Elliott, N Bajalovic, DK Loke
– APL Materials
Antibonding-Induced Anomalous Temperature Dependence of the Band Gap in Crystalline Ge<inf>2</inf>Sb<inf>2</inf>Te<inf>5</inf>
Y Huang, J Zhou, L Peng, K Li, SR Elliott, Z Sun
– The Journal of Physical Chemistry C
Cerebral Microdialysate Metabolite Monitoring using Mid-infrared Spectroscopy
FC Alimagham, D Hutter, N Marco-García, E Gould, VH Highland, A Huefner, S Giorgi-Coll, MJ Killen, AP Zakrzewska, SR Elliott, KLH Carpenter, PJ Hutchinson, T Hutter
– Anal Chem
Alpha Synuclein only Forms Fibrils In Vitro when Larger than its Critical Size of 70 Monomers.
SE Sanchez, DR Whiten, G Meisl, FS Ruggeri, E Hidari, D Klenerman
– Chembiochem