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Yusuf Hamied Department of Chemistry

 

Recent Publications from the Physical Research Interest Group

The Hsc70 Disaggregation Machinery Removes Monomer Units Directly from α-Synuclein Fibril ends
MM Schneider, S Gautam, TW Herling, E Andrzejewska, G Krainer, AM Miller, VA Trinkaus, QAE Peter, FS Ruggeri, M Vendruscolo, A Bracher, CM Dobson, FU Hartl, TPJ Knowles
– Nature communications
(2021)
12,
1
(DOI: 10.1038/s41467-021-25966-w)
Intermolecular reorganisation of single-component condensates during ageing promotes multiphase architectures
A Garaizar, J Espinosa, J Joseph, G Krainer, Y Shen, TPJ Knowles, R Collepardo-Guevara
(2021)
(DOI: 10.1101/2021.10.09.463670)
Accelerating Reaction Rates of Biomolecules by Using Shear Stress in Artificial Capillary Systems
TA Hakala, EV Yates, PK Challa, Z Toprakcioglu, K Nadendla, D Matak-Vinkovic, CM Dobson, R Martínez, F Corzana, TPJ Knowles, GJL Bernardes
– Journal of the American Chemical Society
(2021)
143,
16401
(DOI: 10.1021/jacs.1c03681)
Mechanochemical Synthesis and Physicochemical Characterization of Previously Unreported Praziquantel Solvates with 2-Pyrrolidone and Acetic Acid
D Zanolla, L Gigli, D Hasa, MR Chierotti, M Arhangelskis, N Demitri, W Jones, D Voinovich, B Perissutti
– Pharmaceutics
(2021)
13,
1606
(DOI: 10.3390/pharmaceutics13101606)
New Frontiers for Machine Learning in Protein Science.
AS Morgunov, KL Saar, M Vendruscolo, TPJ Knowles
– Journal of Molecular Biology
(2021)
433,
167232
(DOI: 10.1016/j.jmb.2021.167232)
Sequential storage and release of microdroplets
Z Toprakcioglu, TPJ Knowles
– Microsystems & Nanoengineering
(2021)
7,
76
(DOI: 10.1038/s41378-021-00303-9)
Mechanism of Secondary Nucleation at the Single Fibril Level from Direct Observations of Aβ42 Aggregation.
MR Zimmermann, SC Bera, G Meisl, S Dasadhikari, S Ghosh, S Linse, K Garai, TPJ Knowles
– Journal of the American Chemical Society
(2021)
143,
16621
(DOI: 10.1021/jacs.1c07228)
A Platform for Site-Specific DNA-Antibody Bioconjugation by Using Benzoylacrylic-labelled Oligonucleotides.
J Konč, L Brown, DR Whiten, Y Zuo, P Ravn, D Klenerman, GJL Bernardes
– Angew Chem Int Ed Engl
(2021)
(DOI: 10.1002/anie.202109713)
ChemDataExtractor 2.0: Autopopulated Ontologies for Materials Science.
J Mavračić, CJ Court, T Isazawa, SR Elliott, JM Cole
– Journal of Chemical Information and Modeling
(2021)
61,
4280
(DOI: 10.1021/acs.jcim.1c00446)
Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling
KY Chen, E Jenkins, M Körbel, A Ponjavic, AH Lippert, AM Santos, N Ashman, C O'Brien-Ball, J McBride, D Klenerman, SJ Davis
– Proc Natl Acad Sci U S A
(2021)
118,
e2024250118
(DOI: 10.1073/pnas.2024250118)
Liquid–liquid phase separation underpins the formation of replication factories in rotaviruses
F Geiger, J Acker, G Papa, X Wang, WE Arter, KL Saar, NA Erkamp, R Qi, JP Bravo, S Strauss, G Krainer, OR Burrone, R Jungmann, TP Knowles, H Engelke, A Borodavka
– The EMBO journal
(2021)
e107711
(DOI: 10.15252/embj.2021107711)
The binding of the small heat-shock protein alpha B-crystallin to fibrils of alpha-synuclein is driven by entropic forces
T Scheidt, JA Carozza, CC Kolbe, FA Aprile, O Tkachenko, MMJ Bellaiche, G Meisl, QAE Peter, TW Herling, S Ness, M Castellana-Cruz, JLP Benesch, M Vendruscolo, CM Dobson, P Arosio, TPJ Knowles
– Proc Natl Acad Sci U S A
(2021)
118,
e2108790118
(DOI: 10.1073/pnas.2108790118)
Deformable and Robust Core-Shell Protein Microcapsules Templated by Liquid-Liquid Phase-Separated Microdroplets
Y Xu, Y Shen, TCT Michaels, KN Baumann, D Vigolo, Q Peter, Y Lu, KL Saar, D Vella, H Zhu, B Li, H Yang, APM Guttenplan, M Rodriguez-Garcia, D Klenerman, TPJ Knowles
– Advanced Materials Interfaces
(2021)
8,
2101071
(DOI: 10.1002/admi.202101071)
Impacts of Hydroperoxymethyl Thioformate on the Global Marine Sulfur Budget
MAH Khan, TJ Bannan, R Holland, DE Shallcross, AT Archibald, E Matthews, A Back, J Allan, H Coe, P Artaxo, CJ Percival
– ACS Earth and Space Chemistry
(2021)
5,
2577
(DOI: 10.1021/acsearthspacechem.1c00218)
Single-route delaminated clay composites for efficient visible-light photo-mineralization of antibiotic-resistant bacteria and associated genes in water
CG Ugwuja, D Olorunnisola, A Ogunlaja, OO Adelowo, A Taubert, GA Kolawole, OD Olukanni, JN Uwanibe, AT Kayode, P Hesemann, D Fatta-Kassinos, TAM Msagati, OA Folarin, SM Clarke, EI Unuabonah
– Applied Catalysis B Environmental
(2021)
292,
120143
(DOI: 10.1016/j.apcatb.2021.120143)
The Independent Volcanic Eruption Source Parameter Archive (IVESPA, version 1.0): A new observational database to support explosive eruptive column model validation and development
TJ Aubry, S Engwell, C Bonadonna, G Carazzo, S Scollo, AR Van Eaton, IA Taylor, D Jessop, J Eychenne, M Gouhier, LG Mastin, KL Wallace, S Biass, M Bursik, RG Grainger, AM Jellinek, A Schmidt
– Journal of Volcanology and Geothermal Research
(2021)
417,
107295
(DOI: 10.1016/j.jvolgeores.2021.107295)
A fast, low-energy multi-state phase-change artificial synapse based on uniform partial-state transitions
SX Go, TH Lee, SR Elliott, N Bajalovic, DK Loke
– APL Materials
(2021)
9,
091103
(DOI: 10.1063/5.0056656)
Antibonding-Induced Anomalous Temperature Dependence of the Band Gap in Crystalline Ge<inf>2</inf>Sb<inf>2</inf>Te<inf>5</inf>
Y Huang, J Zhou, L Peng, K Li, SR Elliott, Z Sun
– The Journal of Physical Chemistry C
(2021)
125,
19537
(DOI: 10.1021/acs.jpcc.1c05342)
Cerebral Microdialysate Metabolite Monitoring using Mid-infrared Spectroscopy
FC Alimagham, D Hutter, N Marco-García, E Gould, VH Highland, A Huefner, S Giorgi-Coll, MJ Killen, AP Zakrzewska, SR Elliott, KLH Carpenter, PJ Hutchinson, T Hutter
– Anal Chem
(2021)
93,
11929
(DOI: 10.1021/acs.analchem.1c01149)
Alpha Synuclein only Forms Fibrils In Vitro when Larger than its Critical Size of 70 Monomers.
SE Sanchez, DR Whiten, G Meisl, FS Ruggeri, E Hidari, D Klenerman
– Chembiochem
(2021)
22,
2867
(DOI: 10.1002/cbic.202100285)

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