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Yusuf Hamied Department of Chemistry

 

Recent Publications from the Physical Research Interest Group

Single molecule imaging of protein aggregation in dementia: Methods, insights and prospects
JSH Danial, D Klenerman
– Neurobiology of disease
(2021)
153,
105327
(DOI: 10.1016/j.nbd.2021.105327)
Influence of surfactants on a pre-adsorbed cationic layer: removal and modi fication
FJ Allen, CL Truscott, RJL Welbourn, SM Clarke
– Journal of colloid and interface science
(2021)
588,
427
(DOI: 10.1016/j.jcis.2020.12.047)
Increased respiratory morbidity associated with exposure to a mature volcanic plume from a large Icelandic fissure eruption.
HK Carlsen, E Ilyinskaya, PJ Baxter, A Schmidt, T Thorsteinsson, MA Pfeffer, S Barsotti, F Dominici, RG Finnbjornsdottir, T Jóhannsson, T Aspelund, T Gislason, U Valdimarsdóttir, H Briem, T Gudnason
– Nature communications
(2021)
12,
2161
(DOI: 10.1038/s41467-021-22432-5)
Learning the molecular grammar of protein condensates from sequence determinants and embeddings.
KL Saar, AS Morgunov, R Qi, WE Arter, G Krainer, AA Lee, TPJ Knowles
– Proceedings of the National Academy of Sciences
(2021)
118,
e2019053118
(DOI: 10.1073/pnas.2019053118)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
– J Biol Chem
(2021)
100631
(DOI: 10.1016/j.jbc.2021.100631)
Interactions of alpha-synuclein oligomers with lipid membranes
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
– Biochimica et Biophysica Acta (BBA) - Biomembranes
(2021)
1863,
183536
(DOI: 10.1016/j.bbamem.2020.183536)
The role of clearance mechanisms in the kinetics of pathological protein aggregation involved in neurodegenerative diseases.
TB Thompson, G Meisl, TPJ Knowles, A Goriely
– The Journal of Chemical Physics
(2021)
154,
125101
(DOI: 10.1063/5.0031650)
Scaling analysis reveals the mechanism and rates of prion replication in vivo
G Meisl, T Kurt, I Condado-Morales, C Bett, S Sorce, M Nuvolone, TCT Michaels, D Heinzer, M Avar, SIA Cohen, S Hornemann, A Aguzzi, CM Dobson, CJ Sigurdson, TPJ Knowles
– Nature Structural & Molecular Biology
(2021)
28,
365
(DOI: 10.1038/s41594-021-00565-x)
From Protein Building Blocks to Functional Materials.
Y Shen, A Levin, A Kamada, Z Toprakcioglu, M Rodriguez-Garcia, Y Xu, TPJ Knowles
– ACS nano
(2021)
acsnano.0c08510
(DOI: 10.1021/acsnano.0c08510)
CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice.
L Caló, E Hidari, M Wegrzynowicz, JW Dalley, BL Schneider, M Podgajna, O Anichtchik, E Carlson, D Klenerman, MG Spillantini
– Brain
(2021)
awab076-
(DOI: 10.1093/brain/awab076)
Shear-mediated sol-gel transition of regenerated silk allows the formation of Janus-like microgels
Z Toprakcioglu, TPJ Knowles
– Scientific reports
(2021)
11,
6673
(DOI: 10.1038/s41598-021-85199-1)
2D Constraint Modifies Packing Behaviour: A Halobenzene Monolayer with X3 Halogen-Bonding Motif
JA Davidson, SJ Jenkins, F Gorrec, SM Clarke
– Molecular Physics
(2021)
e1900940
(DOI: 10.1080/00268976.2021.1900940)
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease.
M Perni, A van der Goot, R Limbocker, TJ van Ham, FA Aprile, CK Xu, P Flagmeier, K Thijssen, P Sormanni, G Fusco, SW Chen, PK Challa, JB Kirkegaard, RF Laine, KY Ma, MBD Müller, T Sinnige, JR Kumita, SIA Cohen, R Seinstra, GS Kaminski Schierle, CF Kaminski, D Barbut, A De Simone, TPJ Knowles, M Zasloff, EAA Nollen, M Vendruscolo, CM Dobson
– Frontiers in Cell and Developmental Biology
(2021)
9,
552549
(DOI: 10.3389/fcell.2021.552549)
Tropospheric ozone in CMIP6 simulations
PT Griffiths, LT Murray, G Zeng, YM Shin, NL Abraham, AT Archibald, M Deushi, LK Emmons, IE Galbally, B Hassler, LW Horowitz, J Keeble, J Liu, O Moeini, V Naik, FM O'Connor, N Oshima, D Tarasick, S Tilmes, ST Turnock, O Wild, PJ Young, P Zanis
– Atmospheric Chemistry and Physics
(2021)
21,
4187
(DOI: 10.5194/acp-21-4187-2021)
Sensitivity of modeled Indian monsoon to Chinese and Indian aerosol emissions
P Sherman, M Gao, S Song, AT Archibald, N Luke Abraham, JF Lamarque, D Shindell, G Faluvegi, MB McElroy
– Atmospheric Chemistry and Physics
(2021)
21,
3593
(DOI: 10.5194/acp-21-3593-2021)
Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans
T Sinnige, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, RI Morimoto
– Proc Natl Acad Sci U S A
(2021)
118,
e2021888118
(DOI: 10.1073/pnas.2021888118)
Model physics and chemistry causing intermodel disagreement within the VolMIP-Tambora Interactive Stratospheric Aerosol ensemble
M Clyne, JF Lamarque, MJ Mills, M Khodri, W Ball, S Bekki, SS Dhomse, N Lebas, G Mann, L Marshall, U Niemeier, V Poulain, A Robock, E Rozanov, A Schmidt, A Stenke, T Sukhodolov, C Timmreck, M Toohey, F Tummon, D Zanchettin, Y Zhu, OB Toon
– Atmospheric Chemistry and Physics
(2021)
21,
3317
(DOI: 10.5194/acp-21-3317-2021)
Intercomparison of the representations of the atmospheric chemistry of pre-industrial methane and ozone in earth system and other global chemistry-transport models
RG Derwent, DD Parrish, AT Archibald, M Deushi, SE Bauer, K Tsigaridis, D Shindell, LW Horowitz, MAH Khan, DE Shallcross
– Atmospheric Environment
(2021)
248,
118248
(DOI: 10.1016/j.atmosenv.2021.118248)
Real-time bioprocess monitoring using a mid-infrared fibre-optic sensor
F Alimagham, J Winterburn, B Dolman, PM Domingues, F Everest, M Platkov, S Basov, G Izakson, A Katzir, SR Elliott, T Hutter
– Biochemical Engineering Journal
(2021)
167,
107889
(DOI: 10.1016/j.bej.2020.107889)
An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides
J-M Bonmatin, C Giorio, F Sánchez-Bayo, M Bijleveld van Lexmond
– Environmental science and pollution research international
(2021)
28,
11709
(DOI: 10.1007/s11356-021-12853-6)

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