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Department of Chemistry

 
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease
MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, AY Baev, AV Berezhnov, Z Yao, D Little, B Banushi, AS Al-Menhali, RT Ranasinghe, DR Whiten, R Yapom, KS Dolt, MJ Devine, P Gissen, T Kunath, M Jaganjac, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
– Nature Communications
(2018)
9,
2293
Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research
JK Quint, E Moore, A Lewis, M Hashmi, K Sultana, M Wright, L Smeeth, L Chatzidiakou, R Jones, S Beevers, S Kolozali, F Kelly, B Barratt
– NPJ Prim Care Respir Med
(2018)
28,
21
Characterisation of particle-surface interactions via anharmonic acoustic transduction
C da Silva Granja, N Sandström, I Efimov, VP Ostanin, W van der Wijngaart, D Klenerman, SK Ghosh
– Sensors and Actuators, B: Chemical
(2018)
272,
175
Solution Fibre Spinning Technique for the Fabrication of Tuneable Decellularised Matrix-Laden Fibres and Fibrous Micromembranes.
Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, Y Yan Shery Huang
– Acta Biomater
(2018)
Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery
M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, MC Hardenberg, P Sormanni, T Müller, KL Saar, LWY Roode, J Habchi, G Vecchi, N Fernando, S Casford, EAA Nollen, M Vendruscolo, CM Dobson, TPJ Knowles
– J Neurosci Methods
(2018)
306,
57
Anionic surfactant induced desorption of a cationic surfactant from mica
FJ Allen, CL Truscott, RJL Welbourn, SM Clarke
– Applied Clay Science
(2018)
160,
276
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation.
C Månsson, RTP van Cruchten, U Weininger, X Yang, R Cukalevski, P Arosio, CM Dobson, T Knowles, M Akke, S Linse, C Emanuelsson
– Biochemistry
(2018)
Extrinsic Amyloid-Binding Dyes for the Detection of Individual Protein Aggregates in Solution.
CG Taylor, G Meisl, MH Horrocks, H Zetterberg, TPJ Knowles, D Klenerman
– Anal Chem
(2018)
Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells.
M Horrocks, DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, SF Lee, C Dobson, S Gandhi, M Spillantini, D Klenerman, RT Ranasinghe, SE Sanchez, D Athauda
– Chembiochem
(2018)
Synthesis of transparent dispersions of aluminium hydroxide nanoparticles.
B Chen, J-X Wang, D Wang, X-F Zeng, SM Clarke, J-F Chen
– Nanotechnology
(2018)
29,
305605
Observations of sesquiterpenes and their oxidation products in central Amazonia during the wet and dry seasons
LD Yee, G Isaacman-VanWertz, RA Wernis, M Meng, V Rivera, NM Kreisberg, SV Hering, MS Bering, M Glasius, MA Upshur, A Gray Bé, RJ Thomson, FM Geiger, JH Offenberg, M Lewandowski, I Kourtchev, M Kalberer, S De Sá, ST Martin, ML Alexander, BB Palm, W Hu, P Campuzano-Jost, DA Day, JL Jimenez, Y Liu, KA McKinney, P Artaxo, J Viegas, A Manzi, MB Oliveira, R De Souza, LAT Machado, K Longo, AH Goldstein
– Atmospheric Chemistry and Physics
(2018)
18,
10433
Origin of metastable oligomers and their effects on amyloid fibril self-assembly
F Hasecke, T Miti, C Perez, J Barton, D Schoelzel, L Gremer, CSR Gruening, G Matthews, G Meisl, TPJ Knowles, D Willbold, P Neudecker, H Heise, G Ullah, W Hoyer, M Muschol
– Chemical Science
(2018)
9,
5937
Secondary nucleation in amyloid formation
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, SIA Cohen, TPJ Knowles, S Linse
– Chemical communications (Cambridge, England)
(2018)
54,
8667
The Interactive Stratospheric Aerosol Model Intercomparison Project (ISA-MIP): Motivation and experimental design
C Timmreck, GW Mann, V Aquila, R Hommel, LA Lee, A Schmidt, C Brühl, S Carn, M Chin, SS Dhomse, T Diehl, JM English, MJ Mills, R Neely, J Sheng, M Toohey, D Weisenstein
– Geoscientific Model Development
(2018)
11,
2581
Potential impacts of emissions associated with unconventional hydrocarbon extraction on UK air quality and human health
AT Archibald, C Ordóñez, E Brent, ML Williams
– Air Quality, Atmosphere & Health
(2018)
11,
627
1064 nm Dispersive Raman Micro-Spectroscopy and Optical Trapping of Pharmaceutical Aerosols
PJ Gallimore, NM Davidson, M Kalberer, FD Pope, AD Ward
– Anal Chem
(2018)
Gaussian approximation potential modeling of lithium intercalation in carbon nanostructures
S Fujikake, VL Deringer, TH Lee, M Krynski, SR Elliott, G Csányi
– The Journal of chemical physics
(2018)
148,
241714
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine.
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, GT Heller, G Meisl, SW Chen, JR Kumita, PK Challa, JB Kirkegaard, SIA Cohen, B Mannini, D Barbut, EAA Nollen, C Cecchi, N Cremades, TPJ Knowles, F Chiti, M Zasloff, M Vendruscolo, CM Dobson
– ACS Chem Biol
(2018)
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils
JWP Brown, G Meisl, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
– Chemical communications (Cambridge, England)
(2018)
54,
7854
Determination of Polypeptide Conformation with Nanoscale Resolution in Water
G Ramer, FS Ruggeri, A Levin, TPJ Knowles, A Centrone
– ACS Nano
(2018)
12,
6612