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Yusuf Hamied Department of Chemistry

 

Recent Publications from the Physical Research Interest Group

Lecanemab preferentially binds to smaller aggregates present at early Alzheimer's disease.
E Fertan, JYL Lam, G Albertini, M Dewilde, Y Wu, OES Akingbade, D Böken, EA English, B De Strooper, D Klenerman
– Alzheimer's & dementia : the journal of the Alzheimer's Association
(2025)
21,
e70086
(DOI: 10.1002/alz.70086)
Aggregation of α-synuclein splice isoforms through a phase separation pathway.
A Röntgen, Z Toprakcioglu, ST Dada, OM Morris, TPJ Knowles, M Vendruscolo
– Science Advances
(2025)
11,
eadq5396
(DOI: 10.1126/sciadv.adq5396)
Design and sustainability of polypeptide material systems
SK Yorke, Z Yang, EG Wiita, A Kamada, TPJ Knowles, MJ Buehler
– Nature Reviews Materials
(2025)
1
(DOI: 10.1038/s41578-025-00793-3)
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates.
NA Erkamp, M Farag, Y Qiu, D Qian, T Sneideris, T Wu, TJ Welsh, H Ausserwöger, TJ Krug, G Chauhan, DA Weitz, MD Lew, TPJ Knowles, RV Pappu
– Nature Communications
(2025)
16,
3463
(DOI: 10.1038/s41467-025-58736-z)
Multi‐Model Assessment of Future Hydrogen Soil Deposition and Lifetime Using CMIP6 Data
MAJ Brown, NJ Warwick, AT Archibald
– Geophysical Research Letters
(2025)
52,
(DOI: 10.1029/2024gl113653)
Multi‐Model Assessment of Future Hydrogen Soil Deposition and Lifetime Using CMIP6 Data
MAJ Brown, NJ Warwick, AT Archibald
– Geophysical Research Letters
(2025)
52,
e2024GL113653
(DOI: 10.1029/2024gl113653)
Learning the rules of peptide self-assembly through data mining with large language models
Z Yang, SK Yorke, TPJ Knowles, MJ Buehler
– Science Advances
(2025)
11,
eadv1971
(DOI: 10.1126/sciadv.adv1971)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, G Šneiderienė, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
– Nat Commun
(2025)
16,
2814
(DOI: 10.1038/s41467-025-58142-5)
Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen.
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, TPJ Knowles
– Commun Biol
(2025)
8,
466
(DOI: 10.1038/s42003-025-07909-z)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, G Šneiderienė, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
– Nature Communications
(2025)
16,
2814
(DOI: 10.1038/s41467-025-58142-5)
Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, TPJ Knowles
– Communications Biology
(2025)
8,
466
(DOI: 10.1038/s42003-025-07909-z)
Short-lived reactive components substantially contribute to particulate matter oxidative potential.
SJ Campbell, B Utinger, A Barth, Z Leni, Z-H Zhang, J Resch, K Li, SS Steimer, C Banach, B Gfeller, FPH Wragg, J Westwood, K Wolfer, N Bukowiecki, M Ihalainen, P Yli-Pirilä, M Somero, M Kortelainen, J Louhisalmi, M Sklorz, H Czech, S di Bucchianico, T Streibel, MN Delaval, C Ruger, N Baumlin, M Salathe, Z Fang, M Pardo, S D'Aronco, C Giorio, Z Shi, RM Harrison, DC Green, FJ Kelly, Y Rudich, SE Paulson, O Sippula, R Zimmermann, M Geiser, M Kalberer
– Science Advances
(2025)
11,
eadp8100
(DOI: 10.1126/sciadv.adp8100)
Future Hydrogen Soil Deposition: Multi-model assessment of hydrogen deposition and lifetime
M Brown, A Archibald, N Warwich
(2025)
(DOI: 10.5194/egusphere-egu25-8383)
Quantifying climate implications of a future hydrogen economy using a two-box model
I Dressel, A Archibald, M Brown, N Warwick, P Griffiths
(2025)
(DOI: 10.5194/egusphere-egu25-7461)
The UK Environmental Impacts of Hydrogen Energy Programme
N Warwick, A Archibald, P Dodds, E Nemitz, H ApSimon, J Drewer
(2025)
(DOI: 10.5194/egusphere-egu25-10785)
Oxidative Potential of Indoor Particulate Matter Collected During Campaigns in the UK, Slovenia, and Sweden
A Zherebker, M Williams, C Giorio
(2025)
(DOI: 10.5194/egusphere-egu25-19806)
Atmospheric and climate effects of NOx emissions from Aviation and Rocket launches
W Feng, Y Li, M Chipperfield, J Plane, D Marsh, J Egan, S Chang, A Rap, W Zhang, A Archibald, T Brown, L Revell, A Saiz López, J-P Booth, D Kinnison
(2025)
(DOI: 10.5194/egusphere-egu25-20347)
Ganglioside Lipids Inhibit the Aggregation of the Alzheimer's Amyloid-β Peptide
Z Toprakcioglu, AK Jayaram, TPJ Knowles
– RSC Chem Biol
(2025)
(DOI: 10.1039/d4cb00189c)
Iron speciation in urban atmospheric aerosols: comparison between thermodynamic modelling and direct measurements
C Giorio, CN Borca, A Zherebker, S D’Aronco, M Saidikova, HA Sheikh, RJ Harrison, D Badocco, L Soldà, P Pastore, M Ammann, T Huthwelker
– ACS Earth and Space Chemistry
(2025)
9,
649
(DOI: 10.1021/acsearthspacechem.4c00359)
Fingerprinting disease-derived protein aggregates reveals unique signature of Motor Neuron Disease
D Cox, M Burke, S Milani, MA White, FM Waldron, D Böken, E Lobanova, J Sreedharan, JM Gregory, D Klenerman
(2025)
(DOI: 10.1101/2025.03.04.641150)

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