Researchers from Cambridge and UT Southwestern have, for the first time, visualised molecules inside chromatin droplets, revealing how these structures organise and support cell function.
Professor Alex Forse awarded 2025 Philip Leverhulme Prize
The Forse Group. Image: Alexander Forse courtesy.
Professor Alex Forse has been awarded a 2025 Philip Leverhulme Prize, recognising the outstanding work of the Forse Group in developing innovative materials to tackle climate change.
Breakthrough Imaging Reveals Parkinson’s Protein Clusters in the Brain
The image shows alpha synuclein oligomers (yellow) inside microglia, the immune cells of the brain. These structures have long been hypothesised to exist but not previously directly observed in Parkinson’s disease. Photo credits: TheLeeLab
For the first time, scientists have directly visualised and measured the tiny protein clusters, called alpha-synuclein oligomers, thought to trigger Parkinson’s disease in human brain tissue.