Structural defects in amyloid-β fibrils drive secondary nucleation.
Nature Communications
(2026)
17
1933
(doi: 10.1038/s41467-026-69377-1)
Classification of tauopathies from human brain homogenates through salt-modulated tau amplification
Alzheimer's & dementia : the journal of the Alzheimer's Association
(2026)
22
e71112
(doi: 10.1002/alz.71112)
Metadiffusion: inference-time meta-energy biasing of biomolecular diffusion models
(2026)
(doi: 10.64898/2026.02.10.704873)
Sequencing DNA methylation and hydroxymethylation at co-occurring chromatin features.
Nature communications
(2026)
(doi: 10.1038/s41467-026-69429-6)
Understanding Biology with Machine Learning: Compression, Intelligibility, and Dependency
Artificial Intelligence in the Life Sciences
(2026)
100161
(doi: 10.1016/j.ailsci.2026.100161)
A Bifunctional Small Molecule Degrader of the Long Noncoding RNA MALAT1 Triplex.
Chemistry – A European Journal
(2026)
e00025
(doi: 10.1002/chem.202600025)
5-methylcytosine and 5-hydroxymethylcytosine are synergistic biomarkers for early detection of colorectal cancer
Communications medicine
(2026)
6
15
(doi: 10.1038/s43856-025-01278-8)
The NewroBus platform: engineered humanized anti-TfR1 nanobodies for efficient brain delivery
Cell Communication and Signaling
(2025)
24
69
(doi: 10.1186/s12964-025-02605-1)
Cryo-EM structures of NHEJ assemblies with nucleosomes
Nat Commun
(2025)
17
648
(doi: 10.1038/s41467-025-67376-2)
SurfDiff: protein surface profiling for selective or broadly reactive epitope prioritisation in binder and immunogen design.
bioRxiv
(2025)
2025.12.23.696170
(doi: 10.64898/2025.12.23.696170)
Deep cervical lymphatic-venous anastomosis in dementia: a clinical and mechanistic evaluation
Int J Surg
(2025)
(doi: 10.1097/JS9.0000000000004561)
Controlled Self-Immolative Release of β-Lapachone via an Optimized <i>para</i>-Hydroxybenzyl Linker for Targeted Pancreatic Cancer Therapy.
J Am Chem Soc
(2025)
147
48271
(doi: 10.1021/jacs.5c17598)
Destabilization of Helix III Initiates Early Serum Amyloid A Misfolding by Exposing Its Amyloidogenic Core
The journal of physical chemistry letters
(2025)
16
13190
(doi: 10.1021/acs.jpclett.5c03467)
Commentary on ‘Untargeted CUT&Tag reads are enriched at accessible chromatin and restrict identification of potential G4-forming sequences in G4-targeted CUT&Tag experiments’
Nucleic Acids Res
(2025)
53
gkaf1337
(doi: 10.1093/nar/gkaf1337)
Single-molecule imaging of small aggregates of IAPP in type 2 diabetes serum with rationally-designed antibody-like scaffolds.
Chemical science
(2025)
17
2748
(doi: 10.1039/d5sc01427a)
High-fidelity human chromosome transfer and elimination.
Science
(2025)
390
1038
(doi: 10.1126/science.adv9797)
Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity
Nature Communications
(2025)
16
10285
(doi: 10.1038/s41467-025-65178-0)
Binding Paths: Describing Small Molecule Interactions with Disordered Proteins via Markov State Models
(2025)
(doi: 10.1101/2025.11.19.688850)
Ca2+-driven PDIA6 biomolecular condensation ensures proinsulin folding
Nature Cell Biology
(2025)
27
1952
(doi: 10.1038/s41556-025-01794-8)
A Cathepsin B‐Triggered CO‐Releasing Molecule with a Non‐Toxic Metal Core for Targeted Tumor Delivery
Angewandte Chemie International Edition
(2025)
65
e13808
(doi: 10.1002/anie.202513808)
A Cathepsin B‐Triggered CO‐Releasing Molecule with a Non‐Toxic Metal Core for Targeted Tumor Delivery
Angewandte Chemie
(2025)
138
e13808
(doi: 10.1002/ange.202513808)
Identification of potent high-affinity secondary nucleation inhibitors of Aβ42 aggregation from an ultra-large chemical library using deep docking
Molecular systems biology
(2025)
22
69
(doi: 10.1038/S44320-025-00159-5)
Deep learning assessment of nativeness and pairing likelihood for antibody and nanobody design with AbNatiV2
(2025)
(doi: 10.1101/2025.10.31.685806)
BLOSUM Is All You Learn Generative Antibody Models Reflect Evolutionary Priors
(2025)
(doi: 10.1101/2025.10.26.684652)