Yusuf Hamied Department of Chemistry

Publications by Professor David Spring

Concise synthesis of rare pyrido[1,2- a ]pyrimidin-2-ones and related nitrogen-rich bicyclic scaffolds with a ring-junction nitrogen
TA Alanine, WRJD Galloway, S Bartlett, JJ Ciardiello, TM McGuire, DR Spring
Organic & Biomolecular Chemistry
(2015)
14
(doi: 10.1039/c5ob01784j)
Double Strain‐Promoted Macrocyclization for the Rapid Selection of Cell‐Active Stapled Peptides
YH Lau, Y Wu, M Rossmann, BX Tan, P de Andrade, YS Tan, C Verma, GJ McKenzie, AR Venkitaraman, M Hyvönen, DR Spring
Angewandte Chemie - International Edition
(2015)
54
(doi: 10.1002/anie.201508416)
Double Strain‐Promoted Macrocyclization for the Rapid Selection of Cell‐Active Stapled Peptides
YH Lau, Y Wu, M Rossmann, BX Tan, P de Andrade, YS Tan, C Verma, GJ McKenzie, AR Venkitaraman, M Hyvönen, DR Spring
Angewandte Chemie
(2015)
127
(doi: 10.1002/ange.201508416)
Which microbial factors really are important in Pseudomonas aeruginosa infections?
A Crousilles, E Maunders, S Bartlett, C Fan, E-F Ukor, Y Abdelhamid, Y Baker, A Floto, DR Spring, M Welch
Future Microbiol
(2015)
10
(doi: 10.2217/fmb.15.100)
New Advances in Diversity‐Oriented Synthesis
WRJD Galloway, JE Stokes, DR Spring
(2015)
(doi: 10.1002/9781118771723.ch4)
The Application of Ligand-Mapping Molecular Dynamics Simulations to the Rational Design of Peptidic Modulators of Protein-Protein Interactions.
YS Tan, DR Spring, C Abell, CS Verma
Journal of chemical theory and computation
(2015)
11
(doi: 10.1021/ct5010577)
Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.
L Laraia, G McKenzie, DR Spring, AR Venkitaraman, DJ Huggins
Chem Biol
(2015)
22
(doi: 10.1016/j.chembiol.2015.04.019)
Studies towards the synthesis of indolizin-5(3H)-one derivatives and related 6,5-azabicyclic scaffolds by ring-closing metathesis
MS Frei, MK Bilyard, TA Alanine, WRJD Galloway, JE Stokes, DR Spring
Bioorganic and Medicinal Chemistry
(2015)
23
(doi: 10.1016/j.bmc.2014.11.037)
Divergent and concise total syntheses of dihydrochalcones and 5-deoxyflavones recently isolated from Tacca species and Mimosa diplotricha
TH Sum, TJ Sum, JE Stokes, WRJD Galloway, DR Spring
Tetrahedron
(2015)
71
(doi: 10.1016/j.tet.2015.02.017)
The Pseudomonas Quinolone Signal (PQS)
T Sams, Y Baker, J Hodgkinson, J Gross, D Spring, M Welch
Israel Journal of Chemistry
(2015)
56
(doi: 10.1002/ijch.201400128)
Enantioselective Synthesis of Chromanones via a Peptidic Phosphane Catalyzed Rauhut-Currier Reaction
RJH Scanes, O Grossmann, A Grossmann, DR Spring
Organic letters
(2015)
17
(doi: 10.1021/acs.orglett.5b00971)
A two-component 'double-click' approach to peptide stapling.
YH Lau, Y Wu, P de Andrade, WRJD Galloway, DR Spring
Nature protocols
(2015)
10
(doi: 10.1038/nprot.2015.033)
Divergent and concise total syntheses of dihydrochalcones and 5-deoxyflavones recently isolated from Tacca species and Mimosa diplotricha
TH Sum, TJ Sum, JE Stokes, WRJD Galloway, DR Spring
Tetrahedron
(2015)
71
(doi: 10.1016/j.tet.2015.02.017)
Diversity oriented synthesis of macrocycles using a build/couple/pair/diversity strategy
F Nie, D Kunciw, J Stokes, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
250
A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffolds
A Isidro-Llobet, K Hadje Georgiou, WRJD Galloway, E Giacomini, MR Hansen, G Méndez-Abt, YS Tan, L Carro, HF Sore, DR Spring
Organic and Biomolecular Chemistry
(2015)
13
(doi: 10.1039/c5ob00371g)
Using small molecules to solve big problems
J Stokes, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2015)
250
Studies towards the synthesis of indolizin-5(3H)-one derivatives and related 6,5-azabicyclic scaffolds by ring-closing metathesis
MS Frei, MK Bilyard, TA Alanine, WRJD Galloway, JE Stokes, DR Spring
Bioorganic & medicinal chemistry
(2014)
23
(doi: 10.1016/j.bmc.2014.11.037)
Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation.
Z Walsh, E-R Janeček, JT Hodgkinson, J Sedlmair, A Koutsioubas, DR Spring, M Welch, CJ Hirschmugl, C Toprakcioglu, JR Nitschke, M Jones, OA Scherman
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1406037111)
Linear aliphatic dialkynes as alternative linkers for double-click stapling of p53-derived peptides
YH Lau, P de Andrade, GJ McKenzie, AR Venkitaraman, DR Spring
Chembiochem : a European journal of chemical biology
(2014)
15
(doi: 10.1002/cbic.201402374)
Diversity-Oriented Synthesis of Drug-Like Macrocyclic Scaffolds Using an Orthogonal Organo- and Metal Catalysis Strategy
A Grossmann, S Bartlett, M Janecek, JT Hodgkinson, DR Spring
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201406865)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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