Yusuf Hamied Department of Chemistry

Publications by Professor David Spring

Investigations into the Ullmann biaryl ether synthesis
MJ Scott, JS Parker, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2013)
245
Hydrosilylation in water: A new bioorthogonal reaction?
EC Frye, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2013)
245
Diversity-oriented synthesis and phenotypic screening identifies novel small molecule regulators of mitosis
L Laraia, AR Venkitaraman, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2013)
245
The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with hydrocinnamoyl-derivatized PLHSpTA peptide
P Sledz, M Hyvonen, YS Tan, S Lang, D Spring, C Abell, RB Best
(2012)
(doi: 10.2210/pdb4e67/pdb)
A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds.
KMG O'Connell, HSG Beckmann, L Laraia, HT Horsley, A Bender, AR Venkitaraman, DR Spring
Organic & Biomolecular Chemistry
(2012)
10
(doi: 10.1039/c2ob26272j)
Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics
B Morkunas, WRJD Galloway, M Wright, BM Ibbeson, JT Hodgkinson, KMG O'Connell, N Bartolucci, M Della Valle, M Welch, DR Spring
Organic & biomolecular chemistry
(2012)
10
(doi: 10.1039/c2ob26501j)
Using ligand-mapping simulations to design a ligand selectively targeting a cryptic surface pocket of polo-like kinase 1
YS Tan, P Śledź, S Lang, CJ Stubbs, DR Spring, C Abell, RB Best
Angewandte Chemie (International ed. in English)
(2012)
51
(doi: 10.1002/anie.201205676)
Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria
WRJD Galloway, JT Hodgkinson, S Bowden, M Welch, DR Spring
Trends in Microbiology
(2012)
20
(doi: 10.1016/j.tim.2012.06.003)
Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria
WRJD Galloway, JT Hodgkinson, S Bowden, M Welch, DR Spring
Trends in Microbiology
(2012)
20
(doi: 10.1016/j.tim.2012.06.003)
Palladium-catalysed cross-coupling of vinyldisiloxanes with benzylic and allylic halides and sulfonates
EC Frye, CJ O'Connor, DG Twigg, B Elbert, L Laraia, DG Hulcoop, AR Venkitaraman, DR Spring
Chemistry
(2012)
18
(doi: 10.1002/chem.201200431)
Two-directional synthesis as a tool for diversityoriented synthesis: Synthesis of alkaloid scaffolds
KMG O'Connell, M Díaz-Gavilán, WRJD Galloway, DR Spring
Beilstein Journal of Organic Chemistry
(2012)
8
(doi: 10.3762/bjoc.8.95)
Microwave-assisted preparation of the quorum-sensing molecule 2-heptyl-3-hydroxy-4(1H)-quinolone and structurally related analogs
JT Hodgkinson, WRJD Galloway, M Welch, DR Spring
Nature Protocols
(2012)
7
(doi: 10.1038/nprot.2012.054)
The effect of humidity on the ozonolysis of unsaturated compounds in aerosol particles
JWL Lee, V Carrascón, PJ Gallimore, SJ Fuller, A Björkegren, DR Spring, FD Pope, M Kalberer
Phys Chem Chem Phys
(2012)
14
(doi: 10.1039/c2cp24094g)
Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa.
JT Hodgkinson, WRJD Galloway, M Wright, IK Mati, RL Nicholson, M Welch, DR Spring
Org Biomol Chem
(2012)
10
(doi: 10.1039/c2ob25198a)
Diversity-oriented synthesis: producing chemical tools for dissecting biology.
CJ O' Connor, HSG Beckmann, DR Spring
Chemical Society reviews
(2012)
41
(doi: 10.1039/c2cs35023h)
Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity
S Zheng, L Laraia, CJ O'Connor, D Sorrell, YS Tan, Z Xu, AR Venkitaraman, W Wu, DR Spring
Organic and Biomolecular Chemistry
(2012)
10
(doi: 10.1039/c2ob25065a)
Coumarin-derived transformable fluorescent sensor for Zn2+
Z Xu, X Liu, J Pan, DR Spring
Chemical Communications
(2012)
48
(doi: 10.1039/c2cc30963g)
A concise total synthesis of deoxyschizandrin and exploration of its antiproliferative effects and those of structurally related derivatives
S Zheng, SJ Aves, L Laraia, WRJD Galloway, KG Pike, W Wu, DR Spring
Chemistry A European Journal
(2012)
18
(doi: 10.1002/chem.201103530)
Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity
S Zheng, L Laraia, CJ O' Connor, D Sorrell, YS Tan, Z Xu, AR Venkitaraman, W Wu, DR Spring
Org Biomol Chem
(2012)
10
(doi: 10.1039/c2ob25065a)
Diversity-oriented synthesis
WRJD Galloway, RJ Spandl, A Bender, GL Thomas, M Diaz-Gavilan, KMG O’Connell, DR Spring
(2012)
(doi: 10.1017/cbo9781139021500.007)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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