Quantitatively Mapping Cellular Viscosity with Detailed Organelle Information via a Designed PET Fluorescent Probe
T Liu, X Liu, DR Spring, X Qian, J Cui, Z Xu
– Sci Rep
(2014)
4,
5418
(DOI: 10.1038/srep05418)
The Use of Chlorobenzene as a Probe Molecule in Molecular Dynamics Simulations.
YS Tan, DR Spring, C Abell, C Verma
– J Chem Inf Model
(2014)
54,
1821
(DOI: 10.1021/ci500215x)
Identification of key residues that confer Rhodobacter sphaeroides LPS activity at horse TLR4/MD-2
KL Irvine, M Gangloff, CM Walsh, DR Spring, NJ Gay, CE Bryant
– PLoS ONE
(2014)
9,
e98776
(DOI: 10.1371/journal.pone.0098776)
High content screening of diverse compound libraries identifies potent modulators of tubulin dynamics
L Laraia, J Stokes, A Emery, GJ McKenzie, AR Venkitaraman, DR Spring
– ACS Medicinal Chemistry Letters
(2014)
5,
598
(DOI: 10.1021/ml5000564)
Diversity-oriented synthesis as a tool for identifying new modulators of mitosis.
BM Ibbeson, L Laraia, E Alza, CJ O' Connor, YS Tan, HML Davies, G McKenzie, AR Venkitaraman, DR Spring
– Nature Communications
(2014)
5,
3155
(DOI: 10.1038/ncomms4155)
Functionalised staple linkages for modulating the cellular activity of stapled peptides
YH Lau, P de Andrade, ST Quah, M Rossmann, L Laraia, N Sköld, TJ Sum, PJE Rowling, TL Joseph, C Verma, M Hyvönen, LS Itzhaki, AR Venkitaraman, CJ Brown, DP Lane, DR Spring
– Chem. Sci.
(2014)
5,
1804
(DOI: 10.1039/c4sc00045e)
Small molecule modulation of quorum sensing pathways
DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
247,
Targeting mitochondria in prostate cancer with the rotenoid group of natural products
DA Russell, DR Spring, DE Neal, LG Fryer
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Chemical probes for studying cell-to-cell communication in bacteria
YR Baker, JT Hodgkinson, M Welch, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Unusual Z-selectivity in the Takai olefination: Evidence for a competing chelation reaction mechanism
CE Hagerman, SM Geddis, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Diversity-oriented synthesis on partially saturated heteroaromatic scaffolds
DG Twigg, T Nowak, L Spadola, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Investigating peptide sequence variations for ‘double-click’ stapled p53 peptides
YH Lau, P de Andrade, N Sköld, GJ McKenzie, AR Venkitaraman, C Verma, DP Lane, DR Spring
– Organic & biomolecular chemistry
(2014)
12,
4074
(DOI: 10.1039/c4ob00742e)
Hydrosilylation as a novel bioorthogonal reaction
MK Gupta, EC Frye, TT-L Kwan, F Zhang, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Development of small-molecule inhibitors of Aurora kinase A: TPX2 protein-protein interaction
M Janecek, P Sharma, M Rossmann, G McKenzie, M Hyvoenen, DR Spring, AR Venkitaraman
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Aqeuous hydrosilylation: Application to site-selective protein modification
TT-L Kwan, EC Frye, MK Gupta, M Welch, JW Chin, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Diversity-oriented synthesis of macrocyclic scaffolds based on a quinine core
J Ciardiello, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space.
A Koutsoukas, S Paricharak, WRJD Galloway, DR Spring, AP Ijzerman, RC Glen, D Marcus, A Bender
– J Chem Inf Model
(2013)
54,
230
(DOI: 10.1021/ci400469u)
Virulence in Pectobacterium atrosepticum is regulated by a coincidence circuit involving quorum sensing and the stress alarmone, (p)ppGpp
SD Bowden, A Eyres, JCS Chung, RE Monson, A Thompson, GPC Salmond, DR Spring, M Welch
– Molecular Microbiology
(2013)
90,
457
(DOI: 10.1111/mmi.12369)
Concise copper-catalyzed synthesis of tricyclic biaryl ether-linked aza-heterocyclic ring systems
P Mestichelli, MJ Scott, WRJD Galloway, J Selwyn, JS Parker, DR Spring
– Organic Letters
(2013)
15,
5448
(DOI: 10.1021/ol4025259)
Combating multidrug-resistant bacteria: Current strategies for the discovery of novel antibacterials
KMG O'Connell, JT Hodgkinson, HF Sore, M Welch, GPC Salmond, DR Spring
– Angewandte Chemie - International Edition
(2013)
52,
10706
(DOI: 10.1002/anie.201209979)