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Yusuf Hamied Department of Chemistry

 

Publications by Professor David Spring

Synthesis of Biaryl-Containing Medium-Ring Systems by Organocuprate Oxidation: Applications in the Total Synthesis of Ellagitannin Natural Products
XB Su, GL Thomas, WRJD Galloway, DS Surry, RJ Spandl, DR Spring
– Synthesis
(2009)
2009,
3880
(DOI: 10.1055/s-0029-1218154)
Mastering the chemical language of bacteria.
WRJD Galloway, JT Hodgkinson, M Welch, DR Spring
– Chemistry & biology
(2009)
16,
913
(DOI: 10.1016/j.chembiol.2009.09.006)
3D small-molecule microarrays
DM Marsden, RL Nicholson, M Ladlow, DR Spring
– Chemical communications (Cambridge, England)
(2009)
7107
(DOI: 10.1039/b913665g)
Is synthesis the main hurdle for the generation of diversity in compound libraries for screening?
WR Galloway, DR Spring
– Expert Opin Drug Discov
(2009)
4,
467
(DOI: 10.1517/17460440902916606)
The discovery of antibacterial agents using diversity-oriented synthesis
WRJD Galloway, A Bender, M Welch, DR Spring
– Chem Commun (Camb)
(2009)
2446
(DOI: 10.1039/b816852k)
Synthesis of unprecedented scaffold diversity.
WRJD Galloway, M Diáz-Gavilán, A Isidro-Llobet, DR Spring
– Angew Chem Int Ed Engl
(2009)
48,
1194
(DOI: 10.1002/anie.200805452)
Fluoride-free cross coupling using vinyldisiloxanes
HF Sore, CM Boehner, SJF MacDonald, D Norton, DJ Fox, DR Spring
– Organic & biomolecular chemistry
(2009)
7,
1068
(DOI: 10.1039/b900852g)
Towards quorum-quenching catalytic antibodies.
PB Kapadnis, E Hall, M Ramstedt, WRJD Galloway, M Welch, DR Spring
– Chemical communications (Cambridge, England)
(2008)
538
(DOI: 10.1039/b819819e)
Using chemical probes to investigate the sub-inhibitory effects of azithromycin.
FG Glansdorp, RJ Spandl, JE Swatton, O Loiseleur, M Welch, DR Spring
– Organic & Biomolecular Chemistry
(2008)
6,
4120
(DOI: 10.1039/b813157k)
Identification of an anti-MRSA dihydrofolate reductase inhibitor from a diversity-oriented synthesis
EE Wyatt, WRJD Galloway, GL Thomas, M Welch, O Loiseleur, AT Plowright, DR Spring
– Chemical Communications
(2008)
4962
(DOI: 10.1039/b812901k)
Synthesis of a biotin-labeled quorum-sensing molecule: Towards a general method for target identification
RJ Spandl, RL Nicholson, DM Marsden, JT Hodgkinson, XB Su, GL Thomas, GPC Salmond, M Welch, DR Spring
– Synlett
(2008)
2008,
2122
(DOI: 10.1055/s-2008-1077978)
BIOL 47-Synthesis of a transition-state analog for the hydrolysis of N-acyl homoserine lactones
PB Kapadnis, E Hall, M Welch, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2008)
236,
ORGN 157-Diversity oriented synthesis: From linear aminoalkenes to complex cyclic scaffolds
M Diaz-Gavilan, K O'Connell, F Benfatti, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2008)
236,
Gemmacin B: bringing diversity back into focus.
A Robinson, GL Thomas, RJ Spandl, M Welch, DR Spring
– Organic & biomolecular chemistry
(2008)
6,
2978
(DOI: 10.1039/b809038f)
Diversity-oriented synthesis.
RJ Spandl, M Díaz-Gavilán, KMG O'Connell, GL Thomas, DR Spring
– Chem Rec
(2008)
8,
129
(DOI: 10.1002/tcr.20144)
Exploiting domino enyne metathesis mechanisms for skeletal diversity generation.
RJ Spandl, H Rudyk, DR Spring
– Chemical communications (Cambridge, England)
(2008)
3001
(DOI: 10.1039/b807278g)
Editorial: the chemistry–biology interface
D Spring
– Chem Soc Rev
(2008)
37,
1293
(DOI: 10.1039/b808132h)
Total synthesis of sanguiin H-5.
X Su, DS Surry, RJ Spandl, DR Spring
– Organic letters
(2008)
10,
2593
(DOI: 10.1021/ol8009545)
Anti-MRSA agent discovery using diversity-oriented synthesis.
GL Thomas, RJ Spandl, FG Glansdorp, M Welch, A Bender, J Cockfield, JA Lindsay, C Bryant, DFJ Brown, O Loiseleur, H Rudyk, M Ladlow, DR Spring
– Angewandte Chemie - International Edition
(2008)
47,
2808
(DOI: 10.1002/anie.200705415)
2-Methoxycyclopentyl analogues of a Pseudomonas aeruginosa quorum sensing modulator
LYW Lee, T Hupfield, RL Nicholson, JT Hodgkinson, X Su, GL Thomas, GPC Salmond, M Welch, DR Spring
– Mol Biosyst
(2008)
4,
505
(DOI: 10.1039/b801563e)

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