Yusuf Hamied Department of Chemistry

Publications by Professor David Spring

ORGN 410-Adventures in diversity-oriented synthesis
DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2006)
232
Copper catalyzed oxidation of organozinc halides
X Su, DJ Fox, DT Blackwell, K Tanaka, DR Spring
Chemical communications (Cambridge, England)
(2006)
(doi: 10.1039/b610218b)
Variations on a theme: diverse N-acyl homoserine lactone-mediated quorum sensing mechanisms in gram-negative bacteria.
D Smith, J-H Wang, JE Swatton, P Davenport, B Price, H Mikkelsen, H Stickland, K Nishikawa, N Gardiol, DR Spring, M Welch
Science progress
(2006)
89
(doi: 10.3184/003685006783238335)
Skeletal diversity construction via a branching synthetic strategy
EE Wyatt, S Fergus, W Galloway, A Bender, DJ Fox, AT Plowright, AS Jessiman, M Welch, DR Spring
Chemical Communications
(2006)
(doi: 10.1039/b607710b)
Metabolic and regulatory engineering of Serratia marcescens: mimicking phage-mediated horizontal acquisition of antibiotic biosynthesis and quorum sensing capacities
SJ Coulthurst, NR Williamson, AKP Harris, DR Spring, GPC Salmond
Microbiology (Reading)
(2006)
152
(doi: 10.1099/mic.0.28803-0)
Immunomodulatory effects of Pseudomonas aeruginosa quorum sensing small molecule probes on mammalian macrophages
GL Thomas, CM Bohner, HE Williams, CM Walsh, M Ladlow, M Welch, CE Bryant, DR Spring
Molecular Biosystems
(2006)
2
(doi: 10.1039/b517248a)
Diversity oriented synthesis: A challenge for synthetic chemists
A Bender, S Fergus, WRJD Galloway, FG Glansdorp, DM Marsden, RL Nicholson, RJ Spandl, GL Thomas, EE Wyatt, RC Glen, DR Spring
Ernst Schering Res Found Workshop
(2006)
58
(doi: 10.1007/978-3-540-37635-4_4)
Synthesis and utilization of functionalized polystyrene resins
GL Thomas, C Böhner, M Ladlow, DR Spring
Tetrahedron
(2005)
61
(doi: 10.1016/j.tet.2005.07.118)
The oxidation of organocuprates - an offbeat strategy for synthesis
DS Surry, DR Spring
Chemical Society Reviews
(2005)
35
(doi: 10.1039/b508391p)
Structure-activity relationships of Erwinia carotovora quorum sensing signaling molecules
M Welch, JM Dutton, FG Glansdorp, GL Thomas, DS Smith, SJ Coulthurst, AML Barnard, GPC Salmond, DR Spring
Bioorg Med Chem Lett
(2005)
15
(doi: 10.1016/j.bmcl.2005.06.066)
Cell–cell communication in Gram-negative bacteria
M Welch, H Mikkelsen, JE Swatton, D Smith, GL Thomas, FG Glansdorp, DR Spring
Molecular Biosystems
(2005)
1
(doi: 10.1039/b505796p)
Assessment of structural diversity in combinatorial synthesis
S Fergus, A Bender, DR Spring
Curr Opin Chem Biol
(2005)
9
(doi: 10.1016/j.cbpa.2005.03.004)
Chemical genetics to chemical genomics: small molecules offer big insights
DR Spring
Chemical Society Reviews
(2005)
34
(doi: 10.1039/b312875j)
Aryl – aryl coupling via directed lithiation and oxidation
DS Surry, DJ Fox, SJF Macdonald, DR Spring
Chemical Communications
(2005)
(doi: 10.1039/b501939g)
Synthesis of Medium‐Ring and Iodinated Biaryl Compounds by Organocuprate Oxidation
DS Surry, X Su, DJ Fox, V Franckevicius, SJF Macdonald, DR Spring
Angewandte Chemie (International ed. in English)
(2005)
44
(doi: 10.1002/anie.200462642)
Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips
J Huang, H Zhu, SJ Haggarty, DR Spring, H Hwang, F Jin, M Snyder, SL Schreiber
Proceedings of the National Academy of Sciences of the United States of America
(2004)
101
(doi: 10.1073/pnas.0407117101)
Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips.
J Huang, H Zhu, SJ Haggarty, DR Spring, H Hwang, F Jin, M Snyder, SL Schreiber
Proc Natl Acad Sci U S A
(2004)
101
(doi: 10.1073/pnas.0407117101)
Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation
FG Glansdorp, GL Thomas, JJK Lee, JM Dutton, GPC Salmond, M Welch, DR Spring
Org Biomol Chem
(2004)
2
(doi: 10.1039/B412802H)
Communications blackout? Do N-acylhomoserine-lactone-degrading enzymes have any role in quorum sensing?
DM Roche, JT Byers, DS Smith, FG Glansdorp, DR Spring, M Welch
Microbiology (Reading)
(2004)
150
(doi: 10.1099/mic.0.26977-0)
Complete functionalisation of small and large diameter bromopolystyrene beads; applications for solid-supported reagents, scavengers and diversity-oriented synthesisElectronic supplementary information (ESI) available: experimental techniques, apparatus, characterisation and spectroscopic data. See http://www.rsc.org/suppdata/ob/b4/b406488g/
GL Thomas, M Ladlow, DR Spring
Organic & Biomolecular Chemistry
(2004)
2
(doi: 10.1039/b406488g)
Yusuf Hamied Department of Chemistry
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