Recent applications of Diversity-oriented synthesis towards novel, 3-dimensional fragment collections
SL Kidd, TJ Osberger, N Mateu, HF Sore, DR Spring
– Front Chem
(2018)
6,
460
(DOI: 10.3389/fchem.2018.00460)
Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
PG Flammer, S Dellicour, SG Preston, D Rieger, S Warren, CKW Tan, R Nicholson, R Přichystalová, N Bleicher, J Wahl, NR Faria, OG Pybus, M Pollard, AL Smith
– Proceedings of the Royal Society B
(2018)
285,
20180991
(DOI: 10.1098/rspb.2018.0991)
Synthesis of structurally diverse biflavonoids
TJ Sum, TH Sum, WRJD Galloway, DG Twigg, JJ Ciardiello, DR Spring
– Tetrahedron
(2018)
74,
5089
(DOI: 10.1016/j.tet.2018.05.003)
Synthesis of structurally diverse N-substituted quaternary carbon containing small molecules from α,α-disubstituted propargyl amino esters
N Mateu, SL Kidd, L Kalash, HF Sore, A Madin, A Bender, DR Spring
– Chemistry
(2018)
24,
13681
(DOI: 10.1002/chem.201803143)
Semi-syntheses of the 11-hydroxyrotenoids sumatrol and villosinol.
DA Russell, JJ Freudenreich, HL Stewart, AD Bond, HF Sore, DR Spring
– Organic & Biomolecular Chemistry
(2018)
16,
6395
(DOI: 10.1039/c8ob01919c)
Two-component stapling of biologically active and conformationally constrained peptides: past, present and future
J Iegre, JS Gaynord, NS Robertson, HF Sore, M Hyvönen, DR Spring
– Advanced Therapeutics
(2018)
1,
1800052
(DOI: 10.1002/adtp.201800052)
Novel non-ATP competitive small molecules targeting the CK2 α/β interface
P Brear, AJP North, J Iegre, K Hadje Georgiou, A Lubin, L Carro, W Green, H Sore, M Hyvonen, D Spring
– Bioorganic & Medicinal Chemistry
(2018)
26,
3016
(DOI: 10.1016/j.bmc.2018.05.011)
Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons
E Bilsland, TA Tavella, R Krogh, JE Stokes, A Roberts, J Ajioka, DR Spring, AD Andricopulo, FTM Costa, SG Oliver
– BMC biotechnology
(2018)
18,
22
(DOI: 10.1186/s12896-018-0428-z)
Studies Towards the Synthesis of the Core of Endiandric Acid H
S Zheng, D Yang, R Zhu, DR Spring
– Chemistry of Natural Compounds
(2018)
54,
289
(DOI: 10.1007/s10600-018-2326-y)
Bioinspired Total Synthesis of Bussealin e
DG Twigg, L Baldassarre, EC Frye, WRJD Galloway, DR Spring
– Organic Letters
(2018)
20,
1597
(DOI: 10.1021/acs.orglett.8b00340)
Loving the poison: The methylcitrate cycle and bacterial pathogenesis
SK Dolan, A Wijaya, SM Geddis, DR Spring, R Silva-Rocha, M Welch
– Microbiology
(2018)
164,
251
(DOI: 10.1099/mic.0.000604)
Diversity-oriented synthesis for the generation of N-substituted quaternary carbon containing small molecules from α,α-disubstituted propargyl amino esters
S Kidd, N Mateu-Sanchis, A Madin, D Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)
256,
Highly reactive bis-cyclooctyne-modified diarylethene for SPAAC-mediated cross-linking
AV Strizhak, K Sharma, O Babii, S Afonin, AS Ulrich, IV Komarov, DR Spring
– Organic & biomolecular chemistry
(2018)
16,
8559
(DOI: 10.1039/C8OB02428F)
Synthesis of diverse semi-saturated bicyclic heteroaromatics
H Stewart, T Moss, D Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)
256,
Site-selective generation of stable antibody-drug conjugates via cysteine bridging of native antibodies
S Walsh, S Omarjee, M Hyvonen, J Carroll, D Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)
256,
Second-generation CK2α inhibitors targeting the αd pocket
J Iegre, P Brear, C De Fusco, M Yoshida, SL Mitchell, M Rossmann, L Carro, HF Sore, M Hyvönen, DR Spring
– Chem Sci
(2018)
9,
3041
(DOI: 10.1039/c7sc05122k)
Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein⁻Protein Interactions.
NS Robertson, DR Spring
– Molecules
(2018)
23,
959
(DOI: 10.3390/molecules23040959)
Adventures in Drugging Undruggable Targets
D Spring
– JOURNAL OF PEPTIDE SCIENCE
(2018)
24,
S44
Stapled peptides as a new technology to investigate protein–protein interactions in human platelets
J Iegre, NS Ahmed, JS Gaynord, Y Wu, KM Herlihy, YS Tan, ME Lopes-Pires, R Jha, YH Lau, HF Sore, C Verma, DH O' Donovan, N Pugh, DR Spring
– Chemical Science
(2018)
9,
4638
(DOI: 10.1039/x0xx00000x)
Stereocontrolled Semisyntheses of Elliptone and 12aβ-Hydroxyelliptone
DA Russell, WJS Fong, DG Twigg, HF Sore, DR Spring
– Journal of natural products
(2017)
80,
2751
(DOI: 10.1021/acs.jnatprod.7b00527)