Yusuf Hamied Department of Chemistry

Publications by Professor David Spring

Designed analogues of the aplyronines for next-generation antibody-drug conjugates
R Porter, T Pettigrew, I Paterson, D Spring, J Parker
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
257
Photoswitchable PROTACs: Visible light activated degradation of the androgen receptor
E Fowler, A Hock, D O'Donovan, J Gorman, G Fumagalli, R Friend, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
258
Development of novel CK2 inhibitors: From small molecules to conformationally constrained peptides targeting allosteric binding sites
J Iegre, P Brear, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
257
Water-soluble, stable and azide-reactive strained dialkynes for biocompatible double strain-promoted click chemistry
K Sharma, AV Strizhak, E Fowler, X Wang, W Xu, C Hatt Jensen, Y Wu, HF Sore, YH Lau, M Hyvönen, LS Itzhaki, DR Spring
Organic & biomolecular chemistry
(2019)
17
(doi: 10.1039/c9ob01745c)
A General Approach for the Site-Selective Modification of Native Proteins, Enabling the Generation of Stable and Functional Antibody-Drug Conjugates
SJ Walsh, S Omarjee, WRJD Galloway, TT-L Kwan, HF Sore, JS Parker, M Hyvönen, JS Carroll, DR Spring
Chemical science
(2019)
10
(doi: 10.1039/c8sc04645j)
Sulfatase-cleavable linkers for antibody-drug conjugates (ADCs)
J Bargh, S Walsh, A Isidro-Llobet, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
258
Antimicrobial stapled peptide-drug conjugates
J Gaynord, J Parker, M Welch, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
258
Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products.
SM Geddis, T Coroama, S Forrest, JT Hodgkinson, M Welch, DR Spring
Beilstein journal of organic chemistry
(2018)
14
(doi: 10.3762/bjoc.14.245)
Recent Applications of Diversity-Oriented Synthesis Toward Novel, 3-Dimensional Fragment Collections.
SL Kidd, TJ Osberger, N Mateu, HF Sore, DR Spring
Frontiers in chemistry
(2018)
6
(doi: 10.3389/fchem.2018.00460)
Molecular archaeoparasitology identifies cultural changes in the Medieval Hanseatic trading centre of Lübeck
PG Flammer, S Dellicour, SG Preston, D Rieger, S Warren, CKW Tan, R Nicholson, R Přichystalová, N Bleicher, J Wahl, NR Faria, OG Pybus, M Pollard, AL Smith
Proc Biol Sci
(2018)
285
(doi: 10.1098/rspb.2018.0991)
Synthesis of structurally diverse biflavonoids
TJ Sum, TH Sum, WRJD Galloway, DG Twigg, JJ Ciardiello, DR Spring
Tetrahedron
(2018)
74
(doi: 10.1016/j.tet.2018.05.003)
Synthesis of Structurally Diverse N-Substituted Quaternary-Carbon-Containing Small Molecules from α,α-Disubstituted Propargyl Amino Esters.
N Mateu, SL Kidd, L Kalash, HF Sore, A Madin, A Bender, DR Spring
Chemistry - A European Journal
(2018)
24
(doi: 10.1002/chem.201803143)
Semi-syntheses of the 11-hydroxyrotenoids sumatrol and villosinol
DA Russell, JJ Freudenreich, HL Stewart, AD Bond, HF Sore, DR Spring
Organic & Biomolecular Chemistry
(2018)
16
(doi: 10.1039/c8ob01919c)
Two-component stapling of biologically active and conformationally constrained peptides: past, present and future
J Iegre, JS Gaynord, NS Robertson, HF Sore, M Hyvönen, DR Spring
Advanced Therapeutics
(2018)
1
(doi: 10.1002/adtp.201800052)
Novel non-ATP competitive small molecules targeting the CK2 α/β interface
P Brear, AJP North, J Iegre, K Hadje Georgiou, A Lubin, L Carro, W Green, H Sore, M Hyvonen, D Spring
Bioorganic and Medicinal Chemistry
(2018)
26
(doi: 10.1016/j.bmc.2018.05.011)
Antiplasmodial and trypanocidal activity of violacein and deoxyviolacein produced from synthetic operons
E Bilsland, TA Tavella, R Krogh, JE Stokes, A Roberts, J Ajioka, DR Spring, AD Andricopulo, FTM Costa, SG Oliver
BMC Biotechnol
(2018)
18
(doi: 10.1186/s12896-018-0428-z)
Studies Towards the Synthesis of the Core of Endiandric Acid H
S Zheng, D Yang, R Zhu, DR Spring
Chemistry of Natural Compounds
(2018)
54
(doi: 10.1007/s10600-018-2326-y)
Bioinspired Total Synthesis of Bussealin E
DG Twigg, L Baldassarre, EC Frye, WRJD Galloway, DR Spring
Org Lett
(2018)
20
(doi: 10.1021/acs.orglett.8b00340)
Loving the poison: the methylcitrate cycle and bacterial pathogenesis.
SK Dolan, A Wijaya, SM Geddis, DR Spring, R Silva-Rocha, M Welch
Microbiology (Reading)
(2018)
164
(doi: 10.1099/mic.0.000604)
Site-selective generation of stable antibody-drug conjugates via cysteine bridging of native antibodies
S Walsh, S Omarjee, M Hyvonen, J Carroll, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2018)
256
Yusuf Hamied Department of Chemistry
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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