Yusuf Hamied Department of Chemistry

Publications by Professor David Spring

The role of chemical synthesis in developing RiPP antibiotics.
SM Rowe, DR Spring
Chem Soc Rev
(2021)
50
(doi: 10.1039/d0cs01386b)
Finding Oxford’s medieval Jewry using organic residue analysis, faunal records and historical documents
J Dunne, E Biddulph, P Manix, T Gillard, H Whelton, S Teague, C Champness, LG Broderick, R Nicholson, P Blinkhorn, E Craig-Atkins, B Jervis, R Madgwick, T Hodos, LJE Cramp, RP Evershed
Archaeological and Anthropological Sciences
(2021)
13
(doi: 10.1007/s12520-021-01282-8)
The preservation of ancient DNA in archaeological fish bone
G Ferrari, A Cuevas, AT Gondek-Wyrozemska, R Ballantyne, O Kersten, AH Pálsdóttir, I van der Jagt, AK Hufthammer, I Ystgaard, S Wickler, GF Bigelow, J Harland, R Nicholson, D Orton, B Clavel, S Boessenkool, JH Barrett, B Star
Journal of Archaeological Science
(2021)
126
(doi: 10.1016/j.jas.2020.105317)
Peptides as a platform for targeted therapeutics for cancer: peptide-drug conjugates (PDCs).
BM Cooper, J Iegre, DH O' Donovan, M Ölwegård Halvarsson, DR Spring
Chemical Society Reviews
(2021)
50
(doi: 10.1039/d0cs00556h)
Chemical probes targeting the kinase CK2: A journey outside the catalytic box
J Iegre, EL Atkinson, PD Brear, BM Cooper, M Hyvönen, DR Spring
Org Biomol Chem
(2021)
19
(doi: 10.1039/d1ob00257k)
Site-selective modification strategies in antibody–drug conjugates
SJ Walsh, JD Bargh, FM Dannheim, AR Hanby, H Seki, AJ Counsell, X Ou, E Fowler, N Ashman, Y Takada, A Isidro-Llobet, JS Parker, JS Carroll, DR Spring
Chemical Society reviews
(2020)
50
(doi: 10.1039/d0cs00310g)
Photocatalytic methods for amino acid modification
TA King, J Mandrup Kandemir, SJ Walsh, DR Spring
Chemical Society reviews
(2020)
50
(doi: 10.1039/d0cs00344a)
Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics
J Charoenpattarapreeda, SJ Walsh, JS Carroll, DR Spring
Angewandte Chemie
(2020)
132
(doi: 10.1002/ange.202010090)
Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics
J Charoenpattarapreeda, SJ Walsh, JS Carroll, DR Spring
Angew Chem Int Ed Engl
(2020)
59
(doi: 10.1002/anie.202010090)
Epidemiological insights from a large-scale investigation of intestinal helminths in Medieval Europe.
PG Flammer, H Ryan, SG Preston, S Warren, R Přichystalová, R Weiss, V Palmowski, S Boschert, K Fellgiebel, I Jasch-Boley, M-S Kairies, E Rümmele, D Rieger, B Schmid, B Reeves, R Nicholson, L Loe, C Guy, T Waldron, J Macháček, J Wahl, M Pollard, G Larson, AL Smith
PLoS neglected tropical diseases
(2020)
14
(doi: 10.1371/journal.pntd.0008600)
Adventures in drugging undruggable targets
DR Spring
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
(2020)
63
Divergent Synthesis of Novel Cylindrocyclophanes that Inhibit Methicillin‐Resistant Staphylococcus aureus (MRSA)
JJ Freudenreich, S Bartlett, NS Robertson, SL Kidd, S Forrest, HF Sore, WRJD Galloway, M Welch, DR Spring
Chemmedchem
(2020)
15
(doi: 10.1002/cmdc.202000179)
Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells.
DA Russell, HR Bridges, R Serreli, SL Kidd, N Mateu, TJ Osberger, HF Sore, J Hirst, DR Spring
Journal of natural products
(2020)
83
(doi: 10.1021/acs.jnatprod.9b01224)
Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
SL Kidd, E Fowler, T Reinhardt, T Compton, N Mateu, H Newman, D Bellini, R Talon, J McLoughlin, T Krojer, A Aimon, A Bradley, M Fairhead, P Brear, L Díaz-Sáez, K McAuley, HF Sore, A Madin, DH O'Donovan, KVM Huber, M Hyvönen, F von Delft, CG Dowson, DR Spring
Chemical science
(2020)
11
(doi: 10.1039/d0sc01232g)
2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in Pseudomonas aeruginosa
AC McVey, S Bartlett, M Kajbaf, A Pellacani, V Gatta, P Tammela, DR Spring, M Welch
Int J Mol Sci
(2020)
21
(doi: 10.3390/ijms21072490)
Hotspots API: A Python Package for the Detection of Small Molecule Binding Hotspots and Application to Structure-Based Drug Design.
PR Curran, CJ Radoux, MD Smilova, RA Sykes, AP Higueruelo, AR Bradley, BD Marsden, DR Spring, TL Blundell, AR Leach, WR Pitt, JC Cole
J. Chem. Inf. Model.
(2020)
60
(doi: 10.1021/acs.jcim.9b00996)
Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents.
TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, JS Parker, DR Spring, I Paterson
Chemical Communications
(2020)
56
(doi: 10.1039/c9cc09050a)
Sulfatase-cleavable linkers for antibody-drug conjugates
JD Bargh, SJ Walsh, A Isidro-Llobet, S Omarjee, JS Carroll, DR Spring
Chem Sci
(2020)
11
(doi: 10.1039/c9sc06410a)
Functionalized Double Strain-Promoted Stapled Peptides for Inhibiting the p53-MDM2 Interaction.
K Sharma, AV Strizhak, E Fowler, W Xu, B Chappell, HF Sore, WRJD Galloway, MN Grayson, YH Lau, LS Itzhaki, DR Spring
ACS Omega
(2020)
5
(doi: 10.1021/acsomega.9b03459)
An efficient, stereocontrolled and versatile synthetic route to bicyclic partially saturated privileged scaffolds
HL Stewart, AR Hanby, TA King, AD Bond, TA Moss, HF Sore, DR Spring
Chemical Communications
(2020)
56
(doi: 10.1039/d0cc02728f)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
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