Reconstructing the history of helminth prevalence in the UK
H Ryan, PG Flammer, R Nicholson, L Loe, B Reeves, E Allison, C Guy, IL Doriga, T Waldron, D Walker, C Kirchhelle, G Larson, AL Smith
– PLOS Neglected Tropical Diseases
(2022)
16,
e0010312
(DOI: 10.1371/journal.pntd.0010312)
Development of small cyclic peptides targeting the CK2α/β interface
EL Atkinson, J Iegre, C D'Amore, P Brear, M Salvi, M Hyvönen, DR Spring
– Chem Commun (Camb)
(2022)
58,
4791
(DOI: 10.1039/d2cc00707j)
A unified in vitro to in vivo fluorescence lifetime screening platform yields amyloid β aggregation inhibitors
S Collins, LV Vliet, F Gielen, M Janeček, SW Valladolid, C Poudel, G Fusco, A De Simone, C Michel, C Kaminski, D Spring, F Hollfelder, GK Schierle
(2022)
(DOI: 10.21203/rs.3.rs-1478521/v1)
Divinylpyrimidine reagents generate antibody-drug conjugates with excellent <i>in vivo</i> efficacy and tolerability
SJ Walsh, S Omarjee, FM Dannheim, D-L Couturier, D Bexheti, L Mendil, G Cronshaw, T Fewster, C Gregg, C Brodie, JL Miller, R Houghton, JS Carroll, DR Spring
– Chem Commun (Camb)
(2022)
58,
1962
(DOI: 10.1039/d1cc06766d)
Correction: The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions.
BH Gan, J Gaynord, SM Rowe, T Deingruber, DR Spring
– Chem Soc Rev
(2022)
51,
792
(DOI: 10.1039/d1cs90109e)
Energetics of lipid transport by the ABC transporter MsbA is lipid dependent.
D Guo, H Singh, A Shimoyama, C Guffick, Y Tang, SM Rowe, T Noel, DR Spring, K Fukase, HW van Veen
– Communications biology
(2021)
4,
1379
(DOI: 10.1038/s42003-021-02902-8)
Targeting a Novel KRAS Binding Site: Application of One-Component Stapling of Small (5-6-mer) Peptides
G Fumagalli, RJ Carbajo, JWM Nissink, J Tart, R Dou, AP Thomas, DR Spring
– J Med Chem
(2021)
64,
17287
(DOI: 10.1021/acs.jmedchem.1c01334)
Microscopy and chemical analyses reveal flavone-based woolly fibres extrude from micron-sized holes in glandular trichomes of <i>Dionysia tapetodes</i>
M Bourdon, J Gaynord, KH Müller, G Evans, S Wallis, P Aston, DR Spring, R Wightman
– BMC Plant Biology
(2021)
21,
258
(DOI: 10.1186/s12870-021-03010-9)
Rapid and robust cysteine bioconjugation with vinylheteroarenes
H Seki, SJ Walsh, JD Bargh, JS Parker, J Carroll, DR Spring
– Chemical Science
(2021)
12,
9060
(DOI: 10.1039/d1sc02722k)
Historical Demographic Processes Dominate Genetic Variation in Ancient Atlantic Cod Mitogenomes
L Martínez-García, G Ferrari, T Oosting, R Ballantyne, I van der Jagt, I Ystgaard, J Harland, R Nicholson, S Hamilton-Dyer, HT Baalsrud, MSO Brieuc, LM Atmore, F Burns, U Schmölcke, KS Jakobsen, S Jentoft, D Orton, AK Hufthammer, JH Barrett, B Star
– Frontiers in Ecology and Evolution
(2021)
9,
671281
(DOI: 10.3389/fevo.2021.671281)
The multifaceted nature of antimicrobial peptides: Current synthetic chemistry approaches and future directions
BH Gan, J Gaynord, SM Rowe, T Deingruber, DR Spring
– Chemical Society reviews
(2021)
50,
7820
(DOI: 10.1039/d0cs00729c)
Downfalls of Chemical Probes Acting at the Kinase ATP-Site: CK2 as a Case Study.
EL Atkinson, J Iegre, PD Brear, EA Zhabina, M Hyvönen, DR Spring
– Molecules
(2021)
26,
1977
(DOI: 10.3390/molecules26071977)
A dual-enzyme cleavable linker for antibody–drug conjugates
JD Bargh, SJ Walsh, N Ashman, A Isidro-Llobet, JS Carroll, DR Spring
– Chemical communications (Cambridge, England)
(2021)
57,
3457
(DOI: 10.1039/d1cc00957e)
The role of chemical synthesis in developing RiPP antibiotics.
SM Rowe, DR Spring
– Chemical Society Reviews
(2021)
50,
4245
(DOI: 10.1039/d0cs01386b)
Finding Oxford’s medieval Jewry using organic residue analysis, faunal records and historical documents
J Dunne, E Biddulph, P Manix, T Gillard, H Whelton, S Teague, C Champness, LG Broderick, R Nicholson, P Blinkhorn, E Craig-Atkins, B Jervis, R Madgwick, T Hodos, LJE Cramp, RP Evershed
– Archaeological and Anthropological Sciences
(2021)
13,
48
(DOI: 10.1007/s12520-021-01282-8)
The preservation of ancient DNA in archaeological fish bone
G Ferrari, A Cuevas, AT Gondek-Wyrozemska, R Ballantyne, O Kersten, AH Pálsdóttir, I van der Jagt, AK Hufthammer, I Ystgaard, S Wickler, GF Bigelow, J Harland, R Nicholson, D Orton, B Clavel, S Boessenkool, JH Barrett, B Star
– Journal of Archaeological Science
(2021)
126,
105317
(DOI: 10.1016/j.jas.2020.105317)
Chemical probes targeting the kinase CK2: a journey outside the catalytic box.
J Iegre, EL Atkinson, PD Brear, BM Cooper, M Hyvönen, DR Spring
– Organic & biomolecular chemistry
(2021)
19,
4380
(DOI: 10.1039/d1ob00257k)
Peptides as a platform for targeted therapeutics for cancer: peptide-drug conjugates (PDCs)
BM Cooper, J Iegre, DH O' Donovan, M Ölwegård Halvarsson, DR Spring
– Chemical Society reviews
(2021)
50,
1480
(DOI: 10.1039/d0cs00556h)
Site-selective modification strategies in antibody–drug conjugates
SJ Walsh, JD Bargh, FM Dannheim, AR Hanby, H Seki, AJ Counsell, X Ou, E Fowler, N Ashman, Y Takada, A Isidro-Llobet, JS Parker, JS Carroll, DR Spring
– Chemical Society reviews
(2020)
50,
1305
(DOI: 10.1039/d0cs00310g)
Photocatalytic methods for amino acid modification.
TA King, J Mandrup Kandemir, SJ Walsh, DR Spring
– Chemical Society reviews
(2020)
50,
39
(DOI: 10.1039/d0cs00344a)