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Yusuf Hamied Department of Chemistry

 

Senior Research Associate

Publications

Binding pocket-based design, synthesis and biological evaluation of novel selective BRD4-BD1 inhibitors
J Ma, H Chen, J Yang, Z Yu, P Huang, H Yang, B Zheng, R Liu, Q Li, G Hu, Z Chen
– Bioorganic & Medicinal Chemistry
(2019)
27,
1871
Therapeutic gene regulation using pyrrole–imidazole polyamides
Z Yu, GN Pandian, T Hidaka, H Sugiyama
– Advanced drug delivery reviews
(2019)
147,
66
Dual inhibitors of RAF-MEK-ERK and PI3K-PDK1-AKT pathways: Design, synthesis and preliminary anticancer activity studies of 3-substituted-5-(phenylamino) indolone derivatives
Z Yu, Z Chen, Q Su, S Ye, H Yuan, M Kuai, M Lv, Z Tu, X Yang, R Liu, G Hu, Q Li
– Bioorganic & Medicinal Chemistry
(2019)
27,
944
Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy.
S Asamitsu, S Obata, Z Yu, T Bando, H Sugiyama
– Molecules (Basel, Switzerland)
(2019)
24,
429
Direct Observation of the Double‐Stranded DNA Formation through Metal Ion‐Mediated Base Pairing in the Nanoscale Structure
X Xing, Y Feng, Z Yu, K Hidaka, F Liu, A Ono, H Sugiyama, M Endo
– Chemistry – A European Journal
(2018)
25,
1446
Direct Observation of H3-H4 Octasome by High-Speed AFM.
T Zou, F Hashiya, Y Wei, Z Yu, GN Pandian, H Sugiyama
– Chemistry – A European Journal
(2018)
24,
15998
Orthogonal PNA Dimerization Domains Empower DNA Binders with Cooperativity and Versatility Mimicking that of Transcription Factor Pairs
Z Yu, W-C Hsieh, S Asamitsu, K Hashiya, T Bando, DH Ly, H Sugiyama
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2018)
24,
14183
Synthetic DNA-Binding Inhibitor of HES1 Alters the Notch Signaling Pathway and Induces Neuronal Differentiation.
Y Wei, GN Pandian, Z Yu, T Zou, Y Li, J Darokar, K Hashiya, T Bando, H Sugiyama
– ACS omega
(2018)
3,
3608
Pip-HoGu: An Artificial Assembly with Cooperative DNA Recognition Capable of Mimicking Transcription Factor Pairs
Z Yu, C Guo, Y Wei, K Hashiya, T Bando, H Sugiyama
– Journal of the American Chemical Society
(2018)
140,
2426
UVA irradiation of BrU-substituted DNA in the presence of Hoechst 33258
A Saha, S Kizaki, JH Han, Z Yu, H Sugiyama
– Bioorganic & Medicinal Chemistry
(2017)
26,
37
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Research Group

Email address

zy323@cam.ac.uk