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Yusuf Hamied Department of Chemistry

 

Publications by Professor Steve Ley CBE FRS FMedSci

Flow-Based, Cerium Oxide Enhanced, Low-Level Palladium Sonogashira and Heck Coupling Reactions by Perovskite Catalysts
C Battilocchio, BN Bhawal, R Chorghade, BJ Deadman, JM Hawkins, SV Ley
– Israel Journal of Chemistry
(2013)
54,
371
(DOI: 10.1002/ijch.201300049)
Continuous Flow-Processing of Organometallic Reagents Using an Advanced Peristaltic Pumping System and the Telescoped Flow Synthesis of (<i>E</i>/<i>Z</i>)-Tamoxifen
PRD Murray, DL Browne, JC Pastre, C Butters, D Guthrie, SV Ley
– Organic Process Research & Development
(2013)
17,
1192
(DOI: 10.1021/op4001548)
Flow chemistry syntheses of natural products
JC Pastre, DL Browne, SV Ley
– Chemical Society Reviews
(2013)
42,
8849
(DOI: 10.1039/c3cs60246j)
The application of a monolithic triphenylphosphine reagent for conducting Ramirez <i>gem</i>-dibromoolefination reactions in flow
KA Roper, MB Berry, SV Ley
– Beilstein J Org Chem
(2013)
9,
1781
(DOI: 10.3762/bjoc.9.207)
Scaling Up of Continuous Flow Processes with Gases Using a Tube-in-Tube Reactor: Inline Titrations and Fanetizole Synthesis with Ammonia
JC Pastre, DL Browne, M O'Brien, SV Ley
– Organic Process Research &amp; Development
(2013)
17,
1183
(DOI: 10.1021/op400152r)
The rapid generation of isothiocyanates in flow.
M Baumann, IR Baxendale
– Beilstein journal of organic chemistry
(2013)
9,
1613
(DOI: 10.3762/bjoc.9.184)
Fragment-based hit identification: thinking in 3D.
AD Morley, A Pugliese, K Birchall, J Bower, P Brennan, N Brown, T Chapman, M Drysdale, IH Gilbert, S Hoelder, A Jordan, SV Ley, A Merritt, D Miller, ME Swarbrick, PG Wyatt
– Drug Discov Today
(2013)
18,
1221
(DOI: 10.1016/j.drudis.2013.07.011)
The synthesis of neurotensin antagonist SR 48692 for prostate cancer research
IR Baxendale, S Cheung, MO Kitching, SV Ley, JW Shearman
– Bioorganic and Medicinal Chemistry
(2013)
21,
4378
(DOI: 10.1016/j.bmc.2013.04.075)
A continuous flow solution to achieving efficient aerobic anti-Markovnikov Wacker oxidation
SL Bourne, SV Ley
– Advanced Synthesis and Catalysis
(2013)
355,
1905
(DOI: 10.1002/adsc.201300278)
Camera-enabled techniques for organic synthesis
SV Ley, RJ Ingham, M O'Brien, DL Browne
– Beilstein Journal of Organic Chemistry
(2013)
9,
1051
(DOI: 10.3762/bjoc.9.118)
Flow chemistry approaches directed at improving chemical synthesis
IR Baxendale, L Brocken, CJ Mallia
– Green Processing and Synthesis
(2013)
2,
211
(DOI: 10.1515/gps-2013-0029)
Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release.
C Battilocchio, L Guetzoyan, C Cervetto, L Di Cesare Mannelli, D Frattaroli, IR Baxendale, G Maura, A Rossi, L Sautebin, M Biava, C Ghelardini, M Marcoli, SV Ley
– ACS Medicinal Chemistry Letters
(2013)
4,
704
(DOI: 10.1021/ml400079h)
The synthesis of neurotensin antagonist SR 48692 for prostate cancer research
IR Baxendale, S Cheung, MO Kitching, SV Ley, JW Shearman
– Bioorganic & Medicinal Chemistry
(2013)
21,
4378
(DOI: 10.1016/j.bmc.2013.04.075)
Studies of a Diastereoselective Electrophilic Fluorination Reaction Employing a Cryo-Flow Reactor
K Nakayama, DL Browne, IR Baxendale, SV Ley
– Synlett
(2013)
24,
1298
(DOI: 10.1055/s-0033-1338455)
A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia
C Battilocchio, JM Hawkins, SV Ley
– Organic letters
(2013)
15,
2278
(DOI: 10.1021/ol400856g)
A machine-assisted flow synthesis of SR48692: a probe for the investigation of neurotensin receptor-1.
C Battilocchio, BJ Deadman, N Nikbin, MO Kitching, IR Baxendale, SV Ley
– Chemistry - A European Journal
(2013)
19,
7917
(DOI: 10.1002/chem.201300696)
Continuous Cold without Cryogenic Consumables: Development of a Convenient Laboratory Tool for Low-Temperature Flow Processes
DL Browne, BH Harji, SV Ley
– Chemical Engineering & Technology
(2013)
36,
959
(DOI: 10.1002/ceat.201200581)
Synthesis of spongistatin 2 employing a new route to the EF fragment
H Kraus, A Français, M O’Brien, J Frost, A Diéguez-Vázquez, A Polara, N Baricordi, R Horan, DS Hsu, T Tsunoda, SV Ley
– Chemical Science
(2013)
4,
1989
(DOI: 10.1039/c3sc50304f)
The integration of flow reactors into synthetic organic chemistry
IR Baxendale
– Journal of Chemical Technology & Biotechnology
(2013)
88,
519
(DOI: 10.1002/jctb.4012)
Synthesis of (-)-hennoxazole A: Integrating batch and flow chemistry methods
A Fernández, ZG Levine, M Baumann, S Sulzer-Mossé, C Sparr, S Schläger, A Metzger, IR Baxendale, SV Ley
– Synlett
(2013)
24,
514
(DOI: 10.1055/s-0032-1318109)

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