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Yusuf Hamied Department of Chemistry

 

Publications by Professor Steve Ley CBE FRS FMedSci

Straightforward, Scalable, Solution-Phase Synthesis of Peptide Bonds in Flow.
ZE Wilson, E Lopez, NJ Flodén, C Watkins, G Bianchini, SV Ley
– Journal of flow chemistry
(2025)
15,
67
(DOI: 10.1007/s41981-025-00347-2)
Carbonylative transformations with Pd catalysts supported on bio-degradable urea-based polymer – Part A
M Markovič, P Lopatka, P Koóš, T Soták, A Ház, T Gracza, SV Ley, M Králik
– Catalysis Today
(2024)
441,
114903
(DOI: 10.1016/j.cattod.2024.114903)
Palladium catalysts supported on biodegradable urea-based polymers in synthesis with CO – Part B
M Markovič, P Lopatka, P Koóš, T Soták, A Ház, T Gracza, SV Ley, M Králik
– Catalysis Today
(2024)
440,
114831
(DOI: 10.1016/j.cattod.2024.114831)
Antascomicin B stabilizes FKBP51-Akt1 complexes as a molecular glue.
SC Schäfer, AM Voll, A Bracher, SV Ley, F Hausch
– Bioorganic & Medicinal Chemistry Letters
(2024)
104,
129728
(DOI: 10.1016/j.bmcl.2024.129728)
Continuous flow synthesis enabling reaction discovery
AI Alfano, J García-Lacuna, OM Griffiths, SV Ley, M Baumann
– Chemical Science
(2024)
15,
4618
(DOI: 10.1039/d3sc06808k)
Nitro-Sulfinate Reductive Coupling to Access (Hetero)aryl Sufonamides
SE Gatarz, OM Griffiths, HA Esteves, W Jiao, P Morse, EL Fisher, DC Blakemore, SV Ley
– J Org Chem
(2024)
89,
1898
(DOI: 10.1021/acs.joc.3c02557)
Photoredox-Catalyzed Preparation of Sulfones Using Bis-Piperidine Sulfur Dioxide - An Underutilized Reagent for SO2 Transfer.
OM Griffiths, HA Esteves, DC Emmet, SV Ley
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2024)
30,
e202303976
(DOI: 10.1002/chem.202303976)
Automated multistep synthesis of 2-pyrazolines in continuous flow
SV Ley, R Labes, JC Pastre, RJ Ingham, C Battilocchio, HM Marçon, MCFCB Damião, DN Tran
– Reaction Chemistry and Engineering
(2023)
9,
558
(DOI: 10.1039/d3re00515a)
The Evolution of Flow Chemistry: An Opinion on Factors Driving Innovation.
SL Bourne, F Amann, SV Ley
– Chimia (Aarau)
(2023)
77,
288
(DOI: 10.2533/chimia.2023.288)
Exploring the chemical space of phenyl sulfide oxidation by automated optimization
P Mueller, A Vriza, AD Clayton, OS May, N Govan, S Notman, SV Ley, TW Chamberlain, RA Bourne
– Reaction Chemistry & Engineering
(2023)
8,
538
(DOI: 10.1039/d2re00552b)
Multicomponent Direct Assembly of <i>N</i>-Heterospirocycles Facilitated by Visible-Light-Driven Photocatalysis.
OM Griffiths, SV Ley
– J Org Chem
(2022)
87,
13204
(DOI: 10.1021/acs.joc.2c01684)
Automated multi-objective reaction optimisation: which algorithm should I use?
P Müller, AD Clayton, J Manson, S Riley, OS May, N Govan, S Notman, SV Ley, TW Chamberlain, RA Bourne
– Reaction Chemistry & Engineering
(2022)
7,
987
(DOI: 10.1039/d1re00549a)
Flow Chemistry – Applications
F Darvas, G Dormán, V Hessel, SV Ley
(2021)
1
(DOI: 10.1515/9783110693690)
Flow chemistry - Fundamentals: Second edition
F Darvas, G Dormán, V Hessel, SV Ley
(2021)
1,
1
(DOI: 10.1515/9783110693676)
Outlook, future directions, and emerging applications
SV Ley, OS May, OM Griffiths, K Sowa
(2021)
313
(DOI: 10.1515/9783110693690-011)
Photoredox-Catalyzed Dehydrogenative Csp3-Csp2 Cross-Coupling of Alkylarenes to Aldehydes in Flow.
OM Griffiths, HA Esteves, Y Chen, K Sowa, OS May, P Morse, DC Blakemore, SV Ley
– J Org Chem
(2021)
86,
13559
(DOI: 10.1021/acs.joc.1c01621)
Formation and Utility of Reactive Ketene Intermediates Under Continuous Flow Conditions
HR Smallman, JA Leitch, T McBride, SV Ley, DL Browne
– Tetrahedron: the international journal for the rapid publication of full original research papers and critical reviews in organic chemistr
(2021)
93,
132305
(DOI: 10.1016/j.tet.2021.132305)
CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells.
S Roy, J Sipthorp, B Mahata, J Pramanik, ML Hennrich, A-C Gavin, SV Ley, SA Teichmann
– iScience
(2021)
24,
102485
(DOI: 10.1016/j.isci.2021.102485)
A Comment on Continuous Flow Technologies within the Agrochemical Industry
SV Ley, Y Chen, A Robinson, B Otter, E Godineau, C Battilocchio
– Organic Process Research & Development
(2021)
25,
713
(DOI: 10.1021/acs.oprd.0c00534)
Living with our machines: Towards a more sustainable future
SV Ley, Y Chen, DE Fitzpatrick, OS May
– Current Opinion in Green and Sustainable Chemistry
(2020)
25,
100353
(DOI: 10.1016/j.cogsc.2020.100353)

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