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Yusuf Hamied Department of Chemistry

 

Publications by Professor Steve Ley CBE FRS FMedSci

Integrated Batch and Continuous Flow Process for the Synthesis of Goniothalamin.
J Pastre, P Murray, D Browne, G Brancaglion, R Galaverna, R Pilli, SV Ley
– ACS Omega
(2020)
5,
18472
(DOI: 10.1021/acsomega.0c02390)
Photoredox Generation of Sulfonyl Radicals and Coupling with Electron Deficient Olefins.
SV Ley, Y Chen, N McNamara, O May, T Pillaiyara, D Blakemore
– Organic letters
(2020)
22,
5746
(DOI: 10.1021/acs.orglett.0c01730)
In silico rationalisation of selectivity and reactivity in Pd-catalysed C–H activation reactions
L Cao, M Kabeshov, SV Ley, AA Lapkin
– Beilstein Journal of Organic Chemistry
(2020)
16,
1465
(DOI: 10.3762/bjoc.16.122)
In Silico Rationalisation of Selectivity and Reactivity in Pd-Catalysed C-H Activation Reactions
L Cao, M Kabeshov, S Ley, A Lapkin
(2020)
(DOI: 10.26434/chemrxiv.11961354.v2)
In Silico Rationalisation of Selectivity and Reactivity in Pd-Catalysed C-H Activation Reactions
L Cao, M Kabeshov, S Ley, A Lapkin
(2020)
(DOI: 10.26434/chemrxiv.11961354.v1)
A tutored discourse on microcontrollers, single board computers and their applications to monitor and control chemical reactions
DE Fitzpatrick, M O'Brien, SV Ley
– Reaction Chemistry and Engineering
(2020)
5,
201
(DOI: 10.1039/c9re00407f)
A Practical Method for Continuous Production of sp3‐Rich Compounds from (Hetero)Aryl Halides and Redox‐Active Esters
E Watanabe, Y Chen, O May, SV Ley
– Chemistry – A European Journal
(2019)
26,
186
(DOI: 10.1002/chem.201905048)
Continuous Pd-Catalyzed Carbonylative Cyclization Using Iron Pentacarbonyl as a CO Source
P Lopatka, M Markovič, P Koóš, SV Ley, T Gracza
– The Journal of Organic Chemistry
(2019)
84,
14394
(DOI: 10.1021/acs.joc.9b02453)
CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells
S Roy, J Sipthorp, B Mahata, J Pramanik, M Hennrich, A-C Gavin, S Ley, S Teichmann
(2019)
(DOI: 10.1101/800649)
A new world for chemical synthesis?
S Ley, Y Chen, D Fitzpatrick, O May
– Chimia
(2019)
73,
792
(DOI: 10.2533/chimia.2019.792)
A Photoredox Coupling Reaction of Benzylboronic Esters and Carbonyl Compounds in Batch and Flow.
Y Chen, O May, DC Blakemore, SV Ley
– Org Lett
(2019)
21,
6140
(DOI: 10.1021/acs.orglett.9b02307)
Enabling synthesis in fragment-based drug discovery by reactivity mapping: photoredox-mediated cross-dehydrogenative heteroarylation of cyclic amines.
R Grainger, TD Heightman, SV Ley, F Lima, CN Johnson
– Chemical science
(2019)
10,
2264
(DOI: 10.1039/C8SC04789H)
Direct Oxidation of Csp<SUP>3</SUP>-H bonds using in Situ Generated Trifluoromethylated Dioxirane in Flow
M Lesieur, C Battilocchio, R Labes, J Jacq, C Genicot, SV Ley, P Pasau
– Chemistry
(2019)
25,
1203
(DOI: 10.1002/chem.201805657)
Fast continuous alcohol amination employing a hydrogen borrowing protocol
R Labes, C Mateos, C Battilocchio, Y Chen, P Dingwall, GR Cumming, JA Rincón, MJ Nieves-Remacha, SV Ley
– Green Chemistry
(2019)
21,
59
(DOI: 10.1039/c8gc03328e)
Photochemical Homologation for the Preparation of Aliphatic Aldehydes in Flow
Y Chen, M Leonardi, P Dingwall, R Labes, P Pasau, DC Blakemore, SV Ley
– The Journal of organic chemistry
(2018)
83,
15558
(DOI: 10.1021/acs.joc.8b02721)
Across‐the‐World Automated Optimization and Continuous‐Flow Synthesis of Pharmaceutical Agents Operating Through a Cloud‐Based Server
DE Fitzpatrick, T Maujean, AC Evans, SV Ley
– Angewandte Chemie
(2018)
130,
15348
(DOI: 10.1002/ange.201809080)
Across-the-World Automated Optimization and Continuous-Flow Synthesis of Pharmaceutical Agents Operating Through a Cloud-Based Server
DE Fitzpatrick, T Maujean, AC Evans, SV Ley
– Angewandte Chemie International Edition
(2018)
57,
15128
(DOI: 10.1002/anie.201809080)
Three-Component Assembly of Multiply Substituted Homoallylic Alcohols and Amines Using a Flow Chemistry Photoreactor.
Y Chen, D Blakemore, P Pasau, S Ley
– Organic Letters
(2018)
20,
6569
(DOI: 10.1021/acs.orglett.8b02907)
Integrated plug flow synthesis and crystallisation of pyrazinamide
CD Scott, R Labes, MJ Depardieu, C Battilocchio, MG Davidson, SV Ley, CC Wilson, K Robertson
– Reaction Chemistry & Engineering
(2018)
3,
631
(DOI: 10.1039/C8RE00087E)
In-line separation of multicomponent reaction mixtures using a new semi-continuous supercritical fluid chromatography system
DE Fitzpatrick, RJ Mutton, SV Ley
– Reaction Chemistry & Engineering
(2018)
3,
799
(DOI: 10.1039/c8re00107c)

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