Highly diastereoselective boron and titanium mediated aldol reactions of a mannitol derived 2,3-butanediacetal ethyl ketone
SV Ley, M O'Brien
– Tetrahedron
(2018)
74,
5319
(DOI: 10.1016/j.tet.2018.06.041)
A Convergent Continuous Multistep Process for the Preparation of C4‑Oxime-Substituted Thiazoles
E Godineau, C Battilocchio, M Lehmann, SV Ley, R Labes, L Birnoschi, S Subramanian, CS Prasanna, A Gorde, M Kalbagh, V Khade, A Scherrer, ACC O'sullivan
– Organic Process Research & Development
(2018)
22,
955
(DOI: 10.1021/acs.oprd.8b00095)
A Continuous Multistep Process for the Preparation of 3-Bromo-2-Oxopropanal O-methyl Oxime as a Precursor to Access C4-Oxime-Substituted Thiazoles
SV Ley, E Godineau, C Battilocchio, M Lehmann, R Labes, L Birnoschi, S Subramanian, CS Prasanna, A Gorde, M Kalbagh, V Khade, A Scherrer, AC O'Sullivan
– OPRD
(2018)
(DOI: 10.1021/acs/oprd.8b00095)
Professor Steven V Ley CBE FRS FMedSci
SV Ley
– Tetrahedron
(2018)
74,
3086
(DOI: 10.1016/j.tet.2018.05.047)
Engineering chemistry for the future of organic synthesis
SV Ley
– Tetrahedron
(2018)
74,
3085
(DOI: 10.1016/j.tet.2018.05.046)
Continuous Flow Hydration of Pyrazine-2-carbonitrile in a Manganese Dioxide Column Reactor
C Battilocchio, SH Lau, JM Hawkins, SV Ley
– Organic Syntheses
(2018)
94,
34
(DOI: 10.1002/0471264229.os094.03)
Mimicking the surface and prebiotic chemistry of early Earth using flow chemistry
DJ Ritson, C Battilocchio, SV Ley, JD Sutherland
– Nature communications
(2018)
9,
1821
(DOI: 10.1038/s41467-018-04147-2)
Editorial: Harmonische Zusammenarbeit von Mensch und Maschine in der chemischen Synthese
SV Ley
– Angewandte Chemie
(2018)
130,
5278
(DOI: 10.1002/ange.201802383)
The Engineering of Chemical Synthesis: Humans and Machines Working in Harmony
SV Ley
– Angewandte Chemie (International ed. in English)
(2018)
57,
5182
(DOI: 10.1002/anie.201802383)
Diastereoselective Synthesis of Functionalized Indolines Using in situ Generated Allyl Boronic Species
JA Forni, SH Lau, JS Poh, C Battilocchio, SV Ley, JC Pastre
– Synlett
(2018)
29,
825
(DOI: 10.1055/s-0036-1589164)
Rapid, selective and stable HaloTag-Lb ADH immobilization directly from crude cell extract for the continuous biocatalytic production of chiral alcohols and epoxides
J Döbber, M Pohl, SV Ley, B Musio
– Reaction Chemistry & Engineering
(2018)
3,
8
(DOI: 10.1039/c7re00173h)
9 Immobilized Reagents and Multistep Processes
SV Ley, DL Browne, M O’Brien
(2018)
2018,
273
(DOI: 10.1055/sos-SD-228-00177)
Real-time spectroscopic analysis enabling quantitative and safe consumption of fluoroform during nucleophilic trifluoromethylation in flow.
B Musio, E Gala, SV Ley
– ACS Sustainable Chemistry & Engineering
(2018)
6,
1489
Preparation of homoallylic amines <i>via</i> a three-component coupling process
X Ou, R Labes, C Battilocchio, S Ley
– Organic & biomolecular chemistry
(2018)
16,
6652
(DOI: 10.1039/C8OB01831F)
Immobilized Reagents and Multistep Processes
SV Ley, DL Browne, M O'Brien
(2018)
2018,
273
(DOI: 10.1055/sos-SD-228-00177)
C–H functionalisation of aldehydes using light generated, non-stabilised diazo compounds in flow
P Dingwall, A Greb, LNS Crespin, R Labes, B Musio, J-S Poh, P Pasau, DC Blakemore, SV Ley
– Chemical communications (Cambridge, England)
(2018)
54,
11685
(DOI: 10.1039/c8cc06202a)
Engineering Chemistry to Enable Bioactive Small Molecule Discovery
SV Ley, D Fitzpatrick, C Battilocchio
(2018)
10,
184
Organic Photocatalysis for the Radical Couplings of Boronic Acid Derivatives in Batch and Flow
F Lima, L Grunenberg, HBA Rahman, R Labes, J Sedelmeier, SV Ley
– Chemical communications (Cambridge, England)
(2018)
54,
5606
(DOI: 10.1039/c8cc02169d)
A Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl–Alkyl Cross‐Coupling Reactions
A Greb, J Poh, S Greed, C Battilocchio, P Pasau, DC Blakemore, SV Ley
– Angewandte Chemie
(2017)
129,
16829
(DOI: 10.1002/ange.201710445)
Visible-Light-Mediated Annulation of Electron-Rich Alkenes and Nitrogen-Centered Radicals from N-Sulfonylallylamines: Construction of Chloromethylated Pyrrolidine Derivatives.
LNS Crespin, A Greb, DC Blakemore, SV Ley
– The Journal of Organic Chemistry
(2017)
82,
13093
(DOI: 10.1021/acs.joc.7b02146)