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Yusuf Hamied Department of Chemistry

 

Publications by Professor Steve Ley CBE FRS FMedSci

A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters.
F Lima, UK Sharma, L Grunenberg, D Saha, S Johannsen, J Sedelmeier, EV Van der Eycken, SV Ley
– Angewandte Chemie - International Edition
(2017)
56,
15136
(DOI: 10.1002/anie.201709690)
A Versatile Route to Unstable Diazo Compounds via Oxadiazolines and their Use in Aryl–Alkyl Cross-Coupling Reactions
A Greb, J-S Poh, S Greed, C Battilocchio, P Pasau, DC Blakemore, SV Ley
– Angewandte Chemie International Edition
(2017)
56,
16602
(DOI: 10.1002/anie.201710445)
Continuous Preparation and Use of Dibromoformaldoxime as a Reactive Intermediate for the Synthesis of 3‑Bromoisoxazolines
C Battilocchio, F Bosica, SM Rowe, B Lacerda Abreu, E Godineau, M Lehmann, SV Ley
– Organic Process Research & Development
(2017)
21,
1588
(DOI: 10.1021/acs.oprd.7b00229)
Rapid Continuous Ruthenium-Catalysed Transfer Hydrogenation of Aromatic Nitriles to Primary Amines
R labes, DG Calderon, C Battilocchio, C Mateos, GR Cumming, O de Frutos, JA Rincon, SV Ley
– Synlett
(2017)
28,
2855
(DOI: 10.1055/s-0036-1589096)
Chemoselective Continuous Ru-Catalyzed Hydrogen-Transfer Oppenauer-Type Oxidation of Secondary Alcohols
R Labes, C Battilocchio, C Mateos, GR Cumming, O de Frutos, JA Rincón, K Binder, SV Ley
– Organic Process Research & Development
(2017)
21,
1419
(DOI: 10.1021/acs.oprd.7b00190)
Unveiling the role of boroxines in metal-free carbon-carbon homologations using diazo compounds and boronic acids
C Bomio-Confaglia, Ley, Kabeshov, Battilocchio, lau, lit, ehlert
– Chem Sci
(2017)
8,
6071
(DOI: 10.1039/C7SC02264F)
Flow synthesis of cyclobutanones $\textit{via}$ [2 + 2] cycloaddition of keteneiminium salts and ethylene gas
C Battilocchio, G Iannucci, S Wang, E Godineau, A Krieger, A De Mesmaeker, SV Ley
– Reaction Chemistry & Engineering
(2017)
2,
295
(DOI: 10.1039/C7RE00020K)
A New Methodology for Incorporating Chiral Linkers into Stapled Peptides
JC Serrano, J Sipthorp, W Xu, LS Itzhaki, SV Ley
– Chembiochem : a European journal of chemical biology
(2017)
18,
1066
(DOI: 10.1002/cbic.201700075)
Utilization of flow chemistry in catalysis: New avenues for the selective synthesis of Bis(indolyl)methanes
SS Mohapatra, ZE Wilson, S Roy, SV Ley
– Tetrahedron
(2017)
73,
1812
(DOI: 10.1016/j.tet.2017.02.026)
One-Pot Acid-Catalyzed Ring-Opening/Cyclization/Oxidation of Aziridines with N-Tosylhydrazones: Access to 1,2,4-Triazines
L Crespin, L Biancalana, T Morack, DC Blakemore, SV Ley
– Organic Letters
(2017)
19,
1084
(DOI: 10.1021/acs.orglett.7b00101)
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines
J Poh, S Makai, T von Keutz, DN Tran, C Battilocchio, P Pasau, SV Ley
– Angewandte Chemie
(2017)
129,
1890
(DOI: 10.1002/ange.201611067)
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines
J-S Poh, S Makai, T von Keutz, DN Tran, C Battilocchio, P Pasau, SV Ley
– Angewandte Chemie International Edition
(2017)
56,
1864
(DOI: 10.1002/anie.201611067)
On the Synthesis and Reactivity of 2,3-Dihydropyrrolo[1,2- a ]quinazolin-5(1 H)-ones
CL Sutherell, SV Ley
– Synthesis Germany
(2017)
49,
135
(DOI: 10.1055/s-0035-1562792)
Continuous direct anodic flow oxidation of aromatic hydrocarbons to benzyl amides
MA Kabeshov, B Musio, SV Ley
– Reaction Chemistry & Engineering
(2017)
2,
822
(DOI: 10.1039/c7re00164a)
Engineering chemistry for the future of chemical synthesis
DE Fitzpatrick, SV Ley
– Tetrahedron
(2017)
74,
3087
(DOI: 10.1016/j.tet.2017.08.050)
Engineering chemistry: Integrating batch and flow reactions on a single, automated reactor platform
DE Fitzpatrick, SV Ley
– Reaction Chemistry and Engineering
(2016)
1,
629
(DOI: 10.1039/C6RE00160B)
Visible Light Activation of Boronic Esters Enables Efficient Photoredox C(sp$^2$)-C(sp$^3$) Cross-Couplings in Flow
F Lima, MA Kabeshov, DN Tran, C Battilocchio, J Sedelmeier, G Sedelmeier, B Schenkel, SV Ley
– Angewandte Chemie
(2016)
55,
14291
(DOI: 10.1002/ange.201605548)
Combination of Enabling Technologies to Improve and Describe the Stereoselectivity of Wolff–Staudinger Cascade Reaction
B Musio, F Mariani, EP Śliwiński, MA Kabeshov, H Odajima, SV Ley
– Synthesis Germany
(2016)
48,
3515
(DOI: 10.1055/s-0035-1562579)
Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia
S Picaud, K Leonards, J-P Lambert, O Dovey, C Wells, O Fedorov, O Monteiro, T Fujisawa, C-Y Wang, H Lingard, C Tallant, N Nikbin, L Guetzoyan, R Ingham, SV Ley, P Brennan, S Muller, A Samsonova, A-C Gingras, J Schwaller, G Vassiliou, S Knapp, P Filippakopoulos
– Science Advances
(2016)
2,
e1600760
(DOI: 10.1126/sciadv.1600760)
Continuous Processing and Efficient $\textit{in Situ}$ Reaction Monitoring of a Hypervalent Iodine(III) Mediated Cyclopropanation Using Benchtop NMR Spectroscopy
B Ahmed-Omer, E Sliwinski, JP Cerroti, SV Ley
– Organic Process Research & Development
(2016)
20,
1603
(DOI: 10.1021/acs.oprd.6b00177)

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