Publications | Page 9 | Yusuf Hamied Department of Chemistry

Synthesis and Use of a Trifluoromethylated Azomethine Ylide Precursor: Ethyl 1-Benzyl-trans-5- (trifluoromethyl)pyrrolidine-3-carboxylate

DM Allwood, DL Browne, SV Ley, HE Peterlin, N Languille, M Faul

– Organic Syntheses

(2014)

91,

162

(DOI: 10.15277/orgsyn.091.0162)

Preparation of Unsymmetrical Ketones from Tosylhydrazones and Aromatic Aldehydes via Formyl C–H Bond Insertion

DM Allwood, DC Blakemore, SV Ley

– Organic letters

(2014)

16,

3064

(DOI: 10.1021/ol5011714)

Accelerating spirocyclic polyketide synthesis using flow chemistry

S Newton, CF Carter, CM Pearson, L De C. Alves, H Lange, P Thansandote, SV Ley

– Angewandte Chemie International Edition

(2014)

53,

4915

(DOI: 10.1002/anie.201402056)

Continuous flow chemistry: a discovery tool for new chemical reactivity patterns

J Hartwig, JB Metternich, N Nikbin, A Kirschning, SV Ley

– Org Biomol Chem

(2014)

12,

3611

(DOI: 10.1039/c4ob00662c)

Accelerating Spirocyclic Polyketide Synthesis using Flow Chemistry

S Newton, CF Carter, CM Pearson, L de C Alves, H Lange, P Thansandote, SV Ley

– Angewandte Chemie (International ed. in English)

(2014)

53,

4915

(DOI: 10.1002/anie.201402056)

Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide

RJ Ingham, C Battilocchio, JM Hawkins, SV Ley

– Beilstein journal of organic chemistry

(2014)

10,

641

(DOI: 10.3762/bjoc.10.56)

Mild and Selective Heterogeneous Catalytic Hydration of Nitriles to Amides by Flowing through Manganese Dioxide

C Battilocchio, JM Hawkins, SV Ley

– Org Lett

(2014)

16,

1060

(DOI: 10.1021/ol403591c)

Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor

JA Newby, L Huck, DW Blaylock, PM Witt, SV Ley, DL Browne

– Chemistry A European Journal

(2014)

20,

263

(DOI: 10.1002/chem.201303736)

Fully Automated Sequence-Specific Synthesis of α-Peptides Using Flow Chemistry

KR Knudsen, M Ladlow, Z Bandpey, SV Ley

– Journal of Flow Chemistry

(2014)

(DOI: 10.1556/jfc-d-13-00033)

Machine-assisted synthesis of modulators of the histone reader BRD9 using flow methods of chemistry and frontal affinity chromatography

L Guetzoyan, RJ Ingham, N Nikbin, J Rossignol, M Wolling, M Baumert, NA Burgess-Brown, CM Strain-Damerell, L Shrestha, PE Brennan, O Fedorov, S Knapp, SV Ley

– Medchemcomm

(2014)

540

(DOI: 10.1039/c4md00007b)

Oppenauer oxidation using hydrous zirconia catalysts and cerium oxide enhanced Sonogashira reactions in flow by low-level palladium perovskite catalysts

RS Chorghade, C Battilocchio, SV Ley

– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

(2014)

247,

Highly regioselective lithiation of pyridines bearing an oxetane unit by n-butyllithium.

G Rouquet, DC Blakemore, SV Ley

– Chem. Commun.

(2014)

50,

8908

(DOI: 10.1039/c4cc03766a)

Investigation of a Lithium-Halogen Exchange Flow Process for the Preparation of Boronates by Using a Cryo-Flow Reactor

JA Newby, L Huck, DW Blaylock, PM Witt, SV Ley, DL Browne

– Chemistry – A European Journal

(2013)

20,

263

(DOI: 10.1002/chem.201303736)

Metal-free coupling of saturated heterocyclic sulfonylhydrazones with boronic acids.

DM Allwood, DC Blakemore, AD Brown, SV Ley

– Journal of Organic Chemistry

(2013)

79,

328

(DOI: 10.1021/jo402526z)

Fragment-based hit identification: Thinking in 3D

AD Morley, A Pugliese, K Birchall, J Bower, P Brennan, N Brown, T Chapman, M Drysdale, IH Gilbert, S Hoelder, A Jordan, SV Ley, A Merritt, D Miller, ME Swarbrick, PG Wyatt

– Drug Discovery Today

(2013)

18,

1221

(DOI: 10.1016/j.drudis.2013.07.011)

Abstract B96: Design, synthesis and biological evaluation of a novel allosteric inhibitor of HSET that damages cancer cells with supernumerary centrosomes.

CA Watts, FM Richards, A Bender, PJ Bond, O Korb, O Kern, M Riddick, P Owen, RM Myers, J Raff, F Gergely, DI Jodrell, SV Ley

– Molecular Cancer Therapeutics

(2013)

12,

B96

(DOI: 10.1158/1535-7163.TARG-13-B96)

An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles

M Baumann, IR Baxendale

– Beilstein J Org Chem

(2013)

2265

(DOI: 10.3762/bjoc.9.265)