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Yusuf Hamied Department of Chemistry

 

Publications by Professor Steve Ley CBE FRS FMedSci

Synthesis of (–)-Hennoxazole A: Integrating Batch and Flow Chemistry Methods
A Fernández, ZG Levine, M Baumann, S Sulzer-Mossé, C Sparr, S Schläger, A Metzger, IR Baxendale, SV Ley
– Synlett
(2013)
24,
514
(DOI: 10.1055/s-0032-1318109)
A prototype device for evaporation in batch and flow chemical processes
BJ Deadman, C Battilocchio, E Sliwinski, SV Ley
– Green Chemistry
(2013)
15,
2050
(DOI: 10.1039/c3gc40967h)
A Continuous Flow Solution to Achieving Efficient Aerobic Anti-Markovnikov Wacker Oxidation
SL Bourne, SV Ley
– Advanced Synthesis and Catalysis
(2013)
342,
Flow chemistry synthesis of zolpidem, alpidem and other GABAA agonists and their biological evaluation through the use of in-line frontal affinity chromatography
L Guetzoyan, N Nikbin, IR Baxendale, SV Ley
– Chem. Sci.
(2013)
4,
764
(DOI: 10.1039/c2sc21850j)
Flow Chemistry Syntheses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes
SL Bourne, M O'Brien, S Kasinathan, P Koos, P Tolstoy, DX Hu, RW Bates, B Martin, B Schenkel, SV Ley
– ChemCatChem
(2012)
5,
159
(DOI: 10.1002/cctc.201200778)
An expeditious synthesis of imatinib and analogues utilising flow chemistry methods
MD Hopkin, IR Baxendale, SV Ley
– Org Biomol Chem
(2012)
11,
1822
(DOI: 10.1039/c2ob27002a)
The synthesis of Bcr-Abl inhibiting anticancer pharmaceutical agents imatinib, nilotinib and dasatinib
BJ Deadman, MD Hopkin, IR Baxendale, SV Ley
– Org Biomol Chem
(2012)
11,
1766
(DOI: 10.1039/c2ob27003j)
Synthesis and use of a trifluoromethylated azomethine ylide precursor
G Tran, R Meier, L Harris, DL Browne, SV Ley
– J Org Chem
(2012)
77,
11071
(DOI: 10.1021/jo302052m)
Flow microwave technology and microreactors in synthesis
IR Baxendale, C Hornung, SV Ley, J De Mata Muñoz Molina, A Wikström
– Australian Journal of Chemistry
(2012)
66,
131
(DOI: 10.1071/ch12365)
Synthesis of Enantiomerically Enriched 3‑Amino-2-oxindoles through a Palladium-Mediated Asymmetric Intramolecular Arylation of α‑Ketimino Amides
P Tolstoy, SXY Lee, C Sparr, SV Ley
– Organic Letters
(2012)
14,
4810
(DOI: 10.1021/ol302119j)
The Evolution of Immobilized Reagents and their Application in Flow Chemistry for the Synthesis of Natural Products and Pharmaceutical Compounds
RM Myers, KA Roper, IR Baxendale, SV Ley
(2012)
359
(DOI: 10.1002/9781118342886.ch11)
Convergent total syntheses of callipeltosides A, B, and C
JR Frost, CM Pearson, TN Snaddon, RA Booth, SV Ley
– Angewandte Chemie International Edition
(2012)
51,
9366
(DOI: 10.1002/anie.201204868)
A total synthesis of the ammonium ionophore, (-)-enniatin B
DX Hu, M Bielitza, P Koos, SV Ley
– Tetrahedron Letters
(2012)
53,
4077
(DOI: 10.1016/j.tetlet.2012.05.110)
Continuous multiple liquid-liquid separation: Diazotization of amino acids in flow
DX Hu, M O'Brien, SV Ley
– Organic Letters
(2012)
14,
4246
(DOI: 10.1021/ol301930h)
A prototype continuous-flow liquid–liquid extraction system using open-source technology
M O'Brien, P Koos, DL Browne, SV Ley
– Org Biomol Chem
(2012)
10,
7031
(DOI: 10.1039/c2ob25912e)
A total synthesis of the ammonium ionophore, (−)-enniatin B
DX Hu, M Bielitza, P Koos, SV Ley
– Tetrahedron Letters
(2012)
53,
4077
(DOI: 10.1016/j.tetlet.2012.05.110)
On being green: Can flow chemistry help?
SV Ley
– Chemical Record
(2012)
12,
378
(DOI: 10.1002/tcr.201100041)
A “Catch–React–Release” Method for the Flow Synthesis of 2-Aminopyrimidines and Preparation of the Imatinib Base
RJ Ingham, E Riva, N Nikbin, IR Baxendale, SV Ley
– Org Lett
(2012)
14,
3920
(DOI: 10.1021/ol301673q)
Continuous flow reaction monitoring using an on-line miniature mass spectrometer
DL Browne, S Wright, BJ Deadman, S Dunnage, IR Baxendale, RM Turner, SV Ley
– Rapid Commun Mass Spectrom
(2012)
26,
1999
(DOI: 10.1002/rcm.6312)
Establishing a Flow Process to Coumarin-8-Carbaldehydes as Important Synthetic Scaffolds
J Zak, D Ron, E Riva, HP Harding, BCS Cross, IR Baxendale
– Chemistry A European Journal
(2012)
18,
9901
(DOI: 10.1002/chem.201201039)

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