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Yusuf Hamied Department of Chemistry

 

Publications by Professor Sir Shankar Balasubramanian FMedSci FRS

Genome-wide analysis of a G-quadruplex-specific single-chain antibody that regulates gene expression.
H Fernando, S Sewitz, J Darot, S Tavaré, JL Huppert, S Balasubramanian
– Nucleic Acids Research
(2009)
37,
6716
(DOI: 10.1093/nar/gkp740)
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in <i>Caenorhabditis elegans</i>
NJ Lehrbach, J Armisen, HL Lightfoot, KJ Murfitt, A Bugaut, S Balasubramanian, EA Miska
– Nature Structural and Molecular Biology
(2009)
16,
1016
(DOI: 10.1038/nsmb.1675)
A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics
S-TD Hsu, P Varnai, A Bugaut, AP Reszka, S Neidle, S Balasubramanian
– Journal of the American Chemical Society
(2009)
131,
13399
(DOI: 10.1021/ja904007p)
A small molecule that disrupts G-quadruplex DNA structure and enhances gene expression.
ZAE Waller, SA Sewitz, S-TD Hsu, S Balasubramanian
– Journal of the American Chemical Society
(2009)
131,
12628
(DOI: 10.1021/ja901892u)
G-quadruplex DNA bound by a synthetic ligand is highly dynamic
PV Jena, PS Shirude, B Okumus, K Laxmi-Reddy, F Godde, I Huc, S Balasubramanian, T Ha
– J Am Chem Soc
(2009)
131,
12522
(DOI: 10.1021/ja903408r)
G-quadruplex nucleic acids as therapeutic targets.
S Balasubramanian, S Neidle
– Current opinion in chemical biology
(2009)
13,
345
(DOI: 10.1016/j.cbpa.2009.04.637)
Controlled-folding of a small molecule modulates DNA G-quadruplex recognition.
S Müller, GD Pantoş, R Rodriguez, S Balasubramanian
– Chemical communications (Cambridge, England)
(2008)
80
(DOI: 10.1039/b816861j)
Position and stability are determining factors for translation repression by an RNA G-quadruplex-forming sequence within the 5' UTR of the NRAS proto-oncogene.
S Kumari, A Bugaut, S Balasubramanian
– Biochemistry
(2008)
47,
12664
(DOI: 10.1021/bi8010797)
Accurate whole human genome sequencing using reversible terminator chemistry
DR Bentley, S Balasubramanian, HP Swerdlow, GP Smith, J Milton, CG Brown, KP Hall, DJ Evers, CL Barnes, HR Bignell, JM Boutell, J Bryant, RJ Carter, R Keira Cheetham, AJ Cox, DJ Ellis, MR Flatbush, NA Gormley, SJ Humphray, LJ Irving, MS Karbelashvili, SM Kirk, H Li, X Liu, KS Maisinger, LJ Murray, B Obradovic, T Ost, ML Parkinson, MR Pratt, IMJ Rasolonjatovo, MT Reed, R Rigatti, C Rodighiero, MT Ross, A Sabot, SV Sankar, A Scally, GP Schroth, ME Smith, VP Smith, A Spiridou, PE Torrance, SS Tzonev, EH Vermaas, K Walter, X Wu, L Zhang, MD Alam, C Anastasi, IC Aniebo, DMD Bailey, IR Bancarz, S Banerjee, SG Barbour, PA Baybayan, VA Benoit, KF Benson, C Bevis, PJ Black, A Boodhun, JS Brennan, JA Bridgham, RC Brown, AA Brown, DH Buermann, AA Bundu, JC Burrows, NP Carter, N Castillo, M Chiara E Catenazzi, S Chang, R Neil Cooley, NR Crake, OO Dada, KD Diakoumakos, B Dominguez-Fernandez, DJ Earnshaw, UC Egbujor, DW Elmore, SS Etchin, MR Ewan, M Fedurco, LJ Fraser, KV Fuentes Fajardo, W Scott Furey, D George, KJ Gietzen, CP Goddard, GS Golda, PA Granieri, DE Green, DL Gustafson, NF Hansen, K Harnish, CD Haudenschild, NI Heyer, MM Hims, JT Ho, AM Horgan, K Hoschler, S Hurwitz, DV Ivanov, MQ Johnson, T James, TA Huw Jones, G-D Kang, TH Kerelska, AD Kersey, I Khrebtukova, AP Kindwall, Z Kingsbury, PI Kokko-Gonzales, A Kumar, MA Laurent, CT Lawley, SE Lee, X Lee, AK Liao, JA Loch, M Lok, S Luo, RM Mammen, JW Martin, PG McCauley, P McNitt, P Mehta, KW Moon, JW Mullens, T Newington, Z Ning, B Ling Ng, SM Novo, MJ O'Neill, MA Osborne, A Osnowski, O Ostadan, LL Paraschos, L Pickering, AC Pike, AC Pike, D Chris Pinkard, DP Pliskin, J Podhasky, VJ Quijano, C Raczy, VH Rae, SR Rawlings, A Chiva Rodriguez, PM Roe, J Rogers, MC Rogert Bacigalupo, N Romanov, A Romieu, RK Roth, NJ Rourke, ST Ruediger, E Rusman, RM Sanches-Kuiper, MR Schenker, JM Seoane, RJ Shaw, MK Shiver, SW Short, NL Sizto, JP Sluis, MA Smith, J Ernest Sohna Sohna, EJ Spence, K Stevens, N Sutton, L Szajkowski, CL Tregidgo, G Turcatti, S Vandevondele, Y Verhovsky, SM Virk, S Wakelin, GC Walcott, J Wang, GJ Worsley, J Yan, L Yau, M Zuerlein, J Rogers, JC Mullikin, ME Hurles, NJ McCooke, JS West, FL Oaks, PL Lundberg, D Klenerman, R Durbin, AJ Smith
– Nature
(2008)
456,
53
(DOI: 10.1038/nature07517)
Diarylethynyl Amides That Recognize the Parallel Conformation of Genomic Promoter DNA G-Quadruplexes
J Dash, PS Shirude, S-TD Hsu, S Balasubramanian
– Journal of the American Chemical Society
(2008)
130,
15950
(DOI: 10.1021/ja8046552)
A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.
R Rodriguez, S Müller, JA Yeoman, C Trentesaux, J-F Riou, S Balasubramanian
– Journal of the American Chemical Society
(2008)
130,
15758
(DOI: 10.1021/ja805615w)
FANCJ Is a Structure-specific DNA Helicase Associated with the Maintenance of Genomic G/C Tracts*
TBC London, LJ Barber, G Mosedale, GP Kelly, S Balasubramanian, ID Hickson, SJ Boulton, K Hiom
– J Biol Chem
(2008)
283,
36132
(DOI: 10.1074/jbc.M808152200)
Recognition and discrimination of DNA quadruplexes by acridine-peptide conjugates.
JE Redman, JM Granadino-Roldán, JA Schouten, S Ladame, AP Reszka, S Neidle, S Balasubramanian
– Organic & biomolecular chemistry
(2008)
7,
76
(DOI: 10.1039/b814682a)
G-quadruplexes: The beginning and end of UTRs
JL Huppert, A Bugaut, S Kumari, S Balasubramanian
– Nucleic Acids Res
(2008)
36,
6260
(DOI: 10.1093/nar/gkn511)
Selective recognition of a DNA G-quadruplex by an engineered antibody.
H Fernando, R Rodriguez, S Balasubramanian
– Biochemistry
(2008)
47,
9365
(DOI: 10.1021/bi800983u)
G-quadruplex recognition by bis-indole carboxamides.
J Dash, PS Shirude, S Balasubramanian
– Chemical communications (Cambridge, England)
(2008)
3055
(DOI: 10.1039/b806042h)
Single-molecule analysis of human telomerase monomer.
D Alves, H Li, R Codrington, A Orte, X Ren, D Klenerman, S Balasubramanian
– Nature Chemical Biology
(2008)
4,
287
(DOI: 10.1038/nchembio.82)
Rigid cyanine dye nucleic acid labels
A Fegan, PS Shirude, S Balasubramanian
– Chemical Communications
(2008)
2004
(DOI: 10.1039/b801629a)
Single molecule conformational analysis of the biologically relevant DNA G-quadruplex in the promoter of the proto-oncogene c - MYC
PS Shirude, L Ying, S Balasubramanian
– Chemical communications (Cambridge, England)
(2008)
2007
(DOI: 10.1039/b801465e)
Exploring the Differential Recognition of DNA G‐Quadruplex Targets by Small Molecules Using Dynamic Combinatorial Chemistry
A Bugaut, K Jantos, J-L Wietor, R Rodriguez, JKM Sanders, S Balasubramanian
– Angewandte Chemie (International ed. in English)
(2008)
47,
2677
(DOI: 10.1002/anie.200705589)

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