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Yusuf Hamied Department of Chemistry

 

Publications by Professor Sir Shankar Balasubramanian FMedSci FRS

DNA G-quadruplex structures act as functional elements in α- and β-globin enhancers
C Doyle, K Herka, SM Flynn, L Melidis, S Dhir, S Schoenfelder, D Tannahill, S Balasubramanian
– Genome Biology
(2025)
26,
155
(DOI: 10.1186/s13059-025-03627-1)
Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch
X Zhang, S Dhir, L Melidis, Y Chen, Z Yu, A Simeone, J Spiegel, S Adhikari, S Balasubramanian
– Nature Chemistry
(2025)
17,
875
(DOI: 10.1038/s41557-025-01792-1)
Selective Photocatalytic C-H Oxidation of 5-Methylcytosine in DNA.
T Yan, Y Chen, B Mortishire-Smith, A Simeone, A Hofer, S Balasubramanian
– Angewandte Chemie International Edition
(2024)
64,
e202413593
(DOI: 10.1002/anie.202413593)
Selective Photocatalytic C‐H oxidation of 5‐methylcytosine in DNA
S Balasubramanian, T Yan, Y Chen, B Mortishire-Smith, A Simeone, A Hofer
– Angewandte Chemie
(2024)
137,
e202413593
(DOI: 10.1002/ange.202413593)
Improved simultaneous mapping of epigenetic features and 3D chromatin structure via ViCAR
SM Flynn, S Dhir, K Herka, C Doyle, L Melidis, A Simeone, WWI Hui, RDC Araujo Tavares, S Schoenfelder, D Tannahill, S Balasubramanian
– Genome Biology
(2024)
25,
237
(DOI: 10.1186/s13059-024-03377-6)
Improved simultaneous mapping of epigenetic features and 3D chromatin structure via ViCAR
SM Flynn, S Dhir, K Herka, C Doyle, L Melidis, A Simeone, WWI Hui, RDC Araujo Tavares, S Schoenfelder, D Tannahill, S Balasubramanian
– Genome Biology
(2024)
25,
(DOI: 10.1186/s13059-024-03377-6)
Spatially tuneable multi-omics sequencing using light-driven combinatorial barcoding of molecules in tissues
G Battistoni, S Torres-Garcia, CY Sia, S Corriero, C Boquetale, E Williams, M Alini, N Hemmer, IMAXT consortium, S Balasubramanian, BC Nicholson, G Hannon, D Bressan
(2024)
(DOI: 10.1101/2024.05.20.595040)
An Upstream G‑Quadruplex DNA Structure Can Stimulate Gene Transcription
Y Chen, A Simeone, L Melidis, SM Cuesta, D Tannahill, S Balasubramanian
– ACS Chem Biol
(2024)
19,
736
(DOI: 10.1021/acschembio.3c00775)
G- quadruplex DNA structure is a positive regulator of<i> MYC</i> transcription
I Esain-Garcia, A Kirchner, L Melidis, RDCA Tavares, S Dhir, A Simeone, Z Yu, SK Madden, R Hermann, D Tannahill, S Balasubramanian
– Proc Natl Acad Sci U S A
(2024)
121,
e2320240121
(DOI: 10.1073/pnas.2320240121)
Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis.
MM Simpson, CC Lam, JM Goodman, S Balasubramanian
– Angew Chem Weinheim Bergstr Ger
(2023)
135,
e202304756
(DOI: 10.1002/ange.202304756)
Selective Functionalisation of 5-Methylcytosine by Organic Photoredox Catalysis
MM Simpson, CC Lam, JM Goodman, S Balasubramanian
– Angew Chem Int Ed Engl
(2023)
62,
e202304756
(DOI: 10.1002/anie.202304756)
A Photoredox Reaction for the Selective Modification of 5-Carboxycytosine in DNA.
BJ Mortishire-Smith, SM Becker, A Simeone, L Melidis, S Balasubramanian
– J Am Chem Soc
(2023)
145,
10505
(DOI: 10.1021/jacs.2c12558)
Simultaneous sequencing of genetic and epigenetic bases in DNA
J Füllgrabe, WS Gosal, P Creed, S Liu, CK Lumby, DJ Morley, TWB Ost, AJ Vilella, S Yu, H Bignell, P Burns, T Charlesworth, B Fu, H Fordham, NJ Harding, O Gandelman, P Golder, C Hodson, M Li, M Lila, Y Liu, J Mason, J Mellad, JM Monahan, O Nentwich, A Palmer, M Steward, M Taipale, A Vandomme, RS San-Bento, A Singhal, J Vivian, N Wójtowicz, N Williams, NJ Walker, NCH Wong, GN Yalloway, JD Holbrook, S Balasubramanian
– Nature Biotechnology
(2023)
41,
1457
(DOI: 10.1038/s41587-022-01652-0)
Chem-map: Profiling drug binding to chromatin in cells
Z Yu, J Spiegel, L Melidis, WWI Hui, X Zhang, A Radzevičius, S Balasubramanian
– Nature biotechnology
(2023)
41,
1265
(DOI: 10.1038/s41587-022-01636-0)
DNA G-Quadruplex Recognition in Vitro and in Live Cells by a Structure-Specific Nanobody
S Galli, L Melidis, SM Flynn, D Varshney, A Simeone, J Spiegel, SK Madden, D Tannahill, S Balasubramanian
– Journal of the American Chemical Society
(2022)
144,
23096
(DOI: 10.1021/jacs.2c10656)
Identification of putative reader proteins of 5-methylcytosine and its derivatives in Caenorhabditis elegans RNA
IC Navarro, KM Suen, D Bensaddek, A Tanpure, A Lamond, S Balasubramanian, EA Miska
– Wellcome Open Research
(2022)
7,
282
(DOI: 10.12688/wellcomeopenres.17893.1)
Identification of putative reader proteins of 5-methylcytosine and its derivatives in &lt;i&gt;Caenorhabditis elegans&lt;/i&gt; RNA.
IC Navarro, KM Suen, D Bensaddek, A Tanpure, A Lamond, S Balasubramanian, EA Miska
– Wellcome open research
(2022)
7,
282
(DOI: 10.12688/wellcomeopenres.17893.1)
Self-organization of plasticity and specialization in a primitively social insect
S Patalano, A Alsina, C Gregorio-Rodríguez, M Bachman, S Dreier, I Hernando-Herraez, P Nana, S Balasubramanian, S Sumner, W Reik, S Rulands
– Cell systems
(2022)
13,
768
(DOI: 10.1016/j.cels.2022.08.002)
Early detection of cancer
D Crosby, S Bhatia, KM Brindle, LM Coussens, C Dive, M Emberton, S Esener, RC Fitzgerald, SS Gambhir, P Kuhn, TR Rebbeck, S Balasubramanian
– Science (New York, N.Y.)
(2022)
375,
eaay9040
(DOI: 10.1126/science.aay9040)
Publisher Correction: Single-cell mapping of DNA G-quadruplex structures in human cancer cells
WWI Hui, A Simeone, KG Zyner, D Tannahill, S Balasubramanian
– Scientific reports
(2022)
12,
908
(DOI: 10.17863/CAM.80436)

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