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Yusuf Hamied Department of Chemistry

 

Publications by Professor Sir Shankar Balasubramanian FMedSci FRS

G-quadruplex DNA structures in human stem cells and differentiation
KG Zyner, A Simeone, SM Flynn, C Doyle, G Marsico, S Adhikari, G Portella, D Tannahill, S Balasubramanian
– Nature communications
(2022)
13,
142
(DOI: 10.1038/s41467-021-27719-1)
G-quadruplex DNA structures in human stem cells and differentiation
KG Zyner, A Simeone, SM Flynn, C Doyle, G Marsico, S Adhikari, G Portella, D Tannahill, S Balasubramanian
– Nature Communications
(2022)
13,
142
(DOI: 10.1038/s41467-021-27719-1)
Three-dimensional imaging mass cytometry for highly multiplexed molecular and cellular mapping of tissues and the tumor microenvironment.
L Kuett, R Catena, A Özcan, A Plüss, HR Ali, MA Sa’d, S Alon, S Aparicio, G Battistoni, S Balasubramanian, R Becker, B Bodenmiller, ES Boyden, D Bressan, A Bruna, M Burger, C Caldas, M Callari, IG Cannell, H Casbolt, N Chornay, Y Cui, A Dariush, K Dinh, A Emenari, Y Eyal-Lubling, J Fan, A Fatemi, E Fisher, EA González-Solares, C González-Fernández, D Goodwin, W Greenwood, F Grimaldi, GJ Hannon, S Harris, C Jauset, JA Joyce, ED Karagiannis, T Kovačević, R Kunes, AK Yoldaş, D Lai, E Laks, H Lee, M Lee, G Lerda, Y Li, A McPherson, N Millar, CM Mulvey, I Nugent, CH O’Flanagan, M Paez-Ribes, I Pearsall, F Qosaj, AJ Roth, OM Rueda, T Ruiz, K Sawicka, LA Sepúlveda, SP Shah, A Shea, A Sinha, A Smith, S Tavaré, S Tietscher, I Vázquez-García, SL Vogl, NA Walton, AT Wassie, SS Watson, J Weselak, SA Wild, E Williams, J Windhager, C Xia, P Zheng, X Zhuang, P Schraml, H Moch, N de Souza, B Bodenmiller
– Nature cancer
(2021)
3,
1
(DOI: 10.1038/s43018-021-00301-w)
Single-cell mapping of DNA G-quadruplex structures in human cancer cells
WWI Hui, A Simeone, KG Zyner, D Tannahill, S Balasubramanian
– Scientific Reports
(2021)
11,
23641
(DOI: 10.1038/s41598-021-02943-3)
RNA G-quadruplex structures control ribosomal protein production
D Varshney, SM Cuesta, B Herdy, UB Abdullah, D Tannahill, S Balasubramanian
– Sci Rep
(2021)
11,
22735
(DOI: 10.1038/s41598-021-01847-6)
Chemical profiling of DNA G-quadruplex-interacting proteins in live cells.
S Balasubramanian, X Zhang, J Spiegel, S Adhikari, S Martinez Cuesta
– Nature chemistry
(2021)
13,
626
(DOI: 10.1038/s41557-021-00736-9)
Reduced Bisulfite Sequencing: Quantitative Base-Resolution Sequencing of 5-Formylcytosine
MJ Booth, S Balasubramanian
– Methods Mol Biol
(2021)
2272,
3
(DOI: 10.1007/978-1-0716-1294-1_1)
Promoter G-quadruplex folding precedes transcription and is controlled by chromatin
J Shen, D Varshney, A Simeone, X Zhang, S Adhikari, D Tannahill, S Balasubramanian
– Genome Biology
(2021)
22,
143
(DOI: 10.1186/s13059-021-02346-7)
G-quadruplexes are transcription factor binding hubs in human chromatin.
J Spiegel, SM Cuesta, S Adhikari, R Hänsel-Hertsch, D Tannahill, S Balasubramanian
– Genome Biol
(2021)
22,
117
(DOI: 10.1186/s13059-021-02324-z)
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.
D Georgopoulou, M Callari, OM Rueda, A Shea, A Martin, A Giovannetti, F Qosaj, A Dariush, S-F Chin, LS Carnevalli, E Provenzano, W Greenwood, G Lerda, E Esmaeilishirazifard, M O'Reilly, V Serra, D Bressan, IMAXT Consortium, GB Mills, HR Ali, SS Cosulich, GJ Hannon, A Bruna, C Caldas
– Nature communications
(2021)
12,
1998
(DOI: 10.1038/s41467-021-22303-z)
TET2 is a component of the ER complex and controls 5mC to 5hmC conversion at ER cis-regulatory regions
R broome, I chernukhin, S Jamieson, K Kishore, E Papachristou, S-Q Mao, C Gonzalez Tejedo, A Mahtey, A Groen, C D'Santos, S Balasubramanian, AM farcas, R Siersbaek, J Carroll
– Cell Reports
(2021)
(DOI: 10.1016/j.celrep.2021.108776)
TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions
R Broome, I Chernukhin, S Jamieson, K Kishore, EK Papachristou, S-Q Mao, CG Tejedo, A Mahtey, V Theodorou, AJ Groen, C D'Santos, S Balasubramanian, AM Farcas, R Siersbæk, JS Carroll
– Cell reports
(2021)
34,
108776
(DOI: 10.1016/j.celrep.2021.108776)
Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis
M Nappi, A Hofer, S Balasubramanian, MJ Gaunt
– J Am Chem Soc
(2020)
142,
21484
(DOI: 10.1021/jacs.0c10616)
Single-molecule visualization of DNA G-quadruplex formation in live cells.
M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, X Zhang, J Shen, L-M Needham, SF Lee, D Klenerman, S Balasubramanian
– Nature Chemistry
(2020)
12,
832
(DOI: 10.1038/s41557-020-0506-4)
Genome-wide DNA Methylation Signatures Are Determined by DNMT3A/B Sequence Preferences
S-Q Mao, SM Cuesta, D Tannahill, S Balasubramanian
– Biochemistry
(2020)
59,
2541
(DOI: 10.1021/acs.biochem.0c00339)
Landscape of G-quadruplex DNA structural regions in breast cancer.
R Hänsel-Hertsch, A Simeone, A Shea, WWI Hui, KG Zyner, G Marsico, OM Rueda, A Bruna, A Martin, X Zhang, S Adhikari, D Tannahill, C Caldas, S Balasubramanian
– Nature Genetics
(2020)
52,
878
(DOI: 10.1038/s41588-020-0672-8)
Affinity-Selected Bicyclic Peptide G-Quadruplex Ligands Mimic a Protein-like Binding Mechanism.
KC Liu, K Röder, C Mayer, S Adhikari, DJ Wales, S Balasubramanian
– Journal of the American Chemical Society
(2020)
142,
8367
(DOI: 10.1021/jacs.0c01879)
The regulation and functions of DNA and RNA G-quadruplexes.
D Varshney, J Spiegel, K Zyner, D Tannahill, S Balasubramanian
– Nat Rev Mol Cell Biol
(2020)
21,
459
(DOI: 10.1038/s41580-020-0236-x)
Natural, modified DNA bases
MK Bilyard, S Becker, S Balasubramanian
– Current opinion in chemical biology
(2020)
57,
1
(DOI: 10.1016/j.cbpa.2020.01.014)
A Spontaneous Ring‐Opening Reaction Leads to a Repair‐Resistant Thymine Oxidation Product in Genomic DNA
AB Sahakyan, A Mahtey, F Kawasaki, S Balasubramanian
– Chembiochem : a European journal of chemical biology
(2019)
21,
320
(DOI: 10.1002/cbic.201900484)

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