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Yusuf Hamied Department of Chemistry

 

Publications by Professor Sir Shankar Balasubramanian FMedSci FRS

Single molecule conformational analysis of DNA G-quadruplexes
PS Shirude, S Balasubramanian
– Biochimie
(2008)
90,
1197
(DOI: 10.1016/j.biochi.2008.01.015)
Triarylpyridines: a versatile small molecule scaffold for G-quadruplex recognition.
ZAE Waller, PS Shirude, R Rodriguez, S Balasubramanian
– Chemical Communications
(2008)
1467
(DOI: 10.1039/b718854d)
A Sequence-Independent Study of the Influence of Short Loop Lengths on the Stability and Topology of Intramolecular DNA G-Quadruplexes †
A Bugaut, S Balasubramanian
– Biochemistry
(2007)
47,
689
(DOI: 10.1021/bi701873c)
Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression.
M Bejugam, S Sewitz, PS Shirude, R Rodriguez, R Shahid, S Balasubramanian
– Journal of the American Chemical Society
(2007)
129,
12926
(DOI: 10.1021/ja075881p)
Macrocyclic and helical oligoamides as a new class of G-quadruplex ligands
PS Shirude, ER Gillies, S Ladame, F Godde, K Shin-Ya, I Huc, S Balasubramanian
– J Am Chem Soc
(2007)
129,
11890
(DOI: 10.1021/ja073775h)
ORGN 41-Quinoline oligoamide macrocycle: Selective G quadruplex binding ligand
PS Shirude, E Gillies, S Ladame, F Godde, I Huc, B Okumus, C Joo, S Balasubramanian
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2007)
234,
Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction
R Rodriguez, GD Pantoş, DPN Gonçalves, JKM Sanders, S Balasubramanian
– Angew Chem Int Ed Engl
(2007)
46,
5405
(DOI: 10.1002/anie.200605075)
Single-molecule conformational analysis of G-quadruplex formation in the promoter DNA duplex of the proto-oncogene c-kit.
PS Shirude, B Okumus, L Ying, T Ha, S Balasubramanian
– J Am Chem Soc
(2007)
129,
7484
(DOI: 10.1021/ja070497d)
G-quadruplexes in promoters throughout the human genome
JL Huppert, S Balasubramanian
– Nucleic Acids Research
(2007)
35,
2105
(DOI: 10.1093/nar/gkm109)
An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.
S Kumari, A Bugaut, JL Huppert, S Balasubramanian
– Nature chemical biology
(2007)
3,
218
(DOI: 10.1038/nchembio864)
A Simple Nanomixer for Single‐Molecule Kinetics Measurements
SS White, S Balasubramanian, D Klenerman, L Ying
– Angewandte Chemie (International ed. in English)
(2006)
45,
7540
(DOI: 10.1002/anie.200602289)
A Simple Nanomixer for Single‐Molecule Kinetics Measurements
SS White, S Balasubramanian, D Klenerman, L Ying
– Angewandte Chemie
(2006)
118,
7702
(DOI: 10.1002/ange.200602289)
Discovery of G-quadruplex stabilizing ligands through direct ELISA of a one-bead-one-compound library
JE Redman, S Ladame, AP Reszka, S Neidle, S Balasubramanian
– Organic & biomolecular chemistry
(2006)
4,
4364
(DOI: 10.1039/b611716c)
Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection
A Orte, R Clarke, S Balasubramanian, D Klenerman
– Analytical Chemistry
(2006)
78,
7707
(DOI: 10.1021/ac061122y)
Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling.
G Gavory, MF Symmons, Y Krishnan Ghosh, D Klenerman, S Balasubramanian
– Biochemistry
(2006)
45,
13304
(DOI: 10.1021/bi061150a)
Oxazole-Based Peptide Macrocycles: A New Class of G-Quadruplex Binding Ligands
K Jantos, R Rodriguez, S Ladame, PS Shirude, S Balasubramanian
– J Am Chem Soc
(2006)
128,
13662
(DOI: 10.1021/ja064713e)
Tetramethylpyridiniumporphyrazines--a new class of G-quadruplex inducing and stabilising ligands.
DPN Gonçalves, R Rodriguez, S Balasubramanian, JKM Sanders
– Chem Commun (Camb)
(2006)
4685
(DOI: 10.1039/b611731g)
Synthesis and G-quadruplex binding studies of new 4-<i>N</i>-methylpyridinium porphyrins
DPN Gonçalves, S Ladame, S Balasubramanian, JKM Sanders
– Org Biomol Chem
(2006)
4,
3337
(DOI: 10.1039/b608494j)
Investigating a Quadruplex−Ligand Interaction by Unfolding Kinetics
JJ Green, S Ladame, L Ying, D Klenerman, S Balasubramanian
– Journal of the American Chemical Society
(2006)
128,
9809
(DOI: 10.1021/ja0615425)
A Conserved Quadruplex Motif Located in a Transcription Activation Site of the Human c-kit Oncogene
H Fernando, AP Reszka, J Huppert, S Ladame, S Rankin, AR Venkitaraman, S Neidle, S Balasubramanian
– Biochemistry
(2006)
45,
7854
(DOI: 10.1021/bi0601510)

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