EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling
M Baumdick, Y Brüggemann, M Schmick, G Xouri, O Sabet, L Davis, JW Chin, PIH Bastiaens
– Elife
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Ribosome Subunit Stapling for Orthogonal Translation in <i>E.</i> <i>coli</i>
SD Fried, WH Schmied, C Uttamapinant, JW Chin
– Angewandte Chemie
(2015)
127,
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Ribosome Subunit Stapling for Orthogonal Translation in E. coli.
SD Fried, WH Schmied, C Uttamapinant, JW Chin
– Angew Chem Int Ed Engl
(2015)
54,
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Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog
DT Rogerson, A Sachdeva, K Wang, T Haq, A Kazlauskaite, SM Hancock, N Huguenin-Dezot, MMK Muqit, AM Fry, R Bayliss, JW Chin
– Nat Chem Biol
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11,
496
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Selective, rapid and optically switchable regulation of protein function in live mammalian cells
Y-H Tsai, S Essig, JR James, K Lang, JW Chin
– Nature chemistry
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7,
554
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Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization.
J Madrzak, M Fiedler, CM Johnson, R Ewan, A Knebel, M Bienz, JW Chin
– Nature Communications
(2015)
6,
6718
(DOI: 10.1038/ncomms7718)
Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne.
T Machida, K Lang, L Xue, JW Chin, N Winssinger
– Bioconjug Chem
(2015)
26,
802
Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins
C Uttamapinant, JD Howe, K Lang, V Beránek, L Davis, M Mahesh, NP Barry, JW Chin
– Journal of the American Chemical Society
(2015)
137,
4602
(DOI: 10.1021/ja512838z)
Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers
JS Bett, MS Ritorto, R Ewan, EG Jaffray, S Virdee, JW Chin, A Knebel, T Kurz, M Trost, MH Tatham, RT Hay
– Biochemical Journal
(2015)
466,
489
(DOI: 10.1042/BJ20141349)
Genetic encoding of unnatural amino acids for labeling proteins.
JWK Chin, K Lang, L Davis
– Methods in molecular biology
(2014)
(DOI: 10.1007/978)
Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.
AJ Price, DA Jacques, WA McEwan, AJ Fletcher, S Essig, JW Chin, UD Halambage, C Aiken, LC James
– PLoS Pathogens
(2014)
10,
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(DOI: 10.1371/journal.ppat.1004459)
Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1
WH Schmied, SJ Elsässer, C Uttamapinant, JW Chin
– Journal of the American Chemical Society
(2014)
136,
15577
(DOI: 10.1021/ja5069728)
Genetically Encoded Optochemical Probes for Simultaneous Fluorescence Reporting and Light Activation of Protein Function with Two-Photon Excitation
J Luo, R Uprety, Y Naro, C Chou, DP Nguyen, JW Chin, A Deiters
– Journal of the American Chemical Society
(2014)
136,
15551
(DOI: 10.1021/ja5055862)
Genetic code expansion and bioorthogonal labelling enables cell specific proteomics in an animal
TS Elliott, A Bianco, JW Chin
– Current opinion in chemical biology
(2014)
21,
154
(DOI: 10.1016/j.cbpa.2014.07.001)
HIV-1 capsid binds host cofactors to mediate nuclear import
A Price, D Jacques, S Essig, T Elliott, U Halambage, J Chin, C Aiken, L James
– Acta Crystallographica Section A: Foundations and advances
(2014)
70,
C120
(DOI: 10.1107/S2053273314098799)
Concerted, rapid, quantitative, and site-specific dual labeling of proteins.
A Sachdeva, K Wang, T Elliott, JW Chin
– Journal of the American Chemical Society
(2014)
136,
7785
(DOI: 10.1021/ja4129789)
Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET
K Wang, A Sachdeva, DJ Cox, NM Wilf, K Lang, S Wallace, RA Mehl, JW Chin
– Nature Chemistry
(2014)
6,
393
(DOI: 10.1038/NCHEM.1919)
Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal.
TS Elliott, FM Townsley, A Bianco, RJ Ernst, A Sachdeva, SJ Elsässer, L Davis, K Lang, R Pisa, S Greiss, KS Lilley, JW Chin
– Nature biotechnology
(2014)
32,
465
(DOI: 10.1038/nbt.2860)
Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins.
K Lang, JW Chin
– Chemical reviews
(2014)
114,
4764
(DOI: 10.1021/cr400355w)
Expanding and reprogramming the genetic code of cells and animals.
JW Chin
– Annual Review of Biochemistry
(2014)
83,
379