skip to content
Home

Yusuf Hamied Department of Chemistry

 

Publications by Professor Jason Chin FMedSci FRS

Strain-promoted sydnone bicyclo-[6.1.0]-nonyne cycloaddition†Electronic supplementary information (ESI) available: Full experimental details, 1H/13C NMR spectral data, protein synthesis and purification. See DOI: 10.1039/c3sc53332h.
S Wallace, JW Chin
– Chemical Science
(2014)
5,
1742
(DOI: 10.1039/c3sc53332h)
Genetic encoding of photocaged cysteine allows photoactivation of TEV protease in live mammalian cells.
DP Nguyen, M Mahesh, SJ Elsässer, SM Hancock, C Uttamapinant, JW Chin
– J Am Chem Soc
(2014)
136,
2240
(DOI: 10.1021/ja412191m)
Bioorthogonal reactions for labeling proteins.
K Lang, JW Chin
– ACS Chemical Biology
(2014)
9,
16
(DOI: 10.1021/cb4009292)
Aqeuous hydrosilylation: Application to site-selective protein modification
TT-L Kwan, EC Frye, MK Gupta, M Welch, JW Chin, DR Spring
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
248,
Conformationally Strained <i>trans</i>-Cyclooctene with Improved Stability and Excellent Reactivity in Tetrazine Ligation.
A Darko, S Wallace, O Dmitrenko, MM Machovina, RA Mehl, JW Chin, JM Fox
– Chemical science
(2014)
5,
3770
(DOI: 10.1039/C4SC01348D)
Efficient and Rapid C. elegans Transgenesis by Bombardment and Hygromycin B Selection
I Radman, S Greiss, JW Chin
– PLoS ONE
(2013)
8,
e76019
(DOI: 10.1371/journal.pone.0076019)
Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells.
J Hemphill, C Chou, JW Chin, A Deiters
– J Am Chem Soc
(2013)
135,
13433
(DOI: 10.1021/ja4051026)
Fluorescent imaging: Shining a light into live cells.
K Lang, JW Chin
– Nature Chemistry
(2013)
5,
81
(DOI: 10.1038/nchem.1555)
Genetically encoded alkenes for protein-bioconjugation reactions
J Torres-Kolbus, C Chou, A Prokup, K Lang, L Davis, J Chin, A Deiters
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2013)
245,
DAXX envelops an H3.3-H4 dimer for H3.3-specific recognition
SJ Elsässer, H Huang, PW Lewis, JW Chin, CD Allis, DJ Patel
– Nature
(2012)
491,
560
(DOI: 10.1038/nature11608)
CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication
AJ Price, AJ Fletcher, T Schaller, T Elliott, K Lee, VN KewalRamani, JW Chin, GJ Towers, LC James
– PLoS Pathog
(2012)
8,
e1002896
(DOI: 10.1371/journal.ppat.1002896)
Expanding the genetic code of Drosophila melanogaster
A Bianco, FM Townsley, S Greiss, K Lang, JW Chin
– Nat Chem Biol
(2012)
8,
748
(DOI: 10.1038/nchembio.1043)
A different life?
JW Chin, L You
– Current opinion in chemical biology
(2012)
16,
243
(DOI: 10.1016/j.cbpa.2012.07.009)
Photocontrol of Tyrosine Phosphorylation in Mammalian Cells via Genetic Encoding of Photocaged Tyrosine
E Arbely, J Torres-Kolbus, A Deiters, JW Chin
– J Am Chem Soc
(2012)
134,
11912
(DOI: 10.1021/ja3046958)
Genetic Encoding of bicyclononynes and trans-cyclooctenes for site-specific protein labeling in vitro and in live mammalian cells via rapid fluorogenic Diels-Alder reactions.
K Lang, L Davis, S Wallace, M Mahesh, DJ Cox, ML Blackman, JM Fox, JW Chin
– J Am Chem Soc
(2012)
134,
10317
(DOI: 10.1021/ja302832g)
Molecular biology. Reprogramming the genetic code.
JW Chin
– Science
(2012)
336,
428
(DOI: 10.1126/science.1221761)
Reprogramming the Genetic Code
JW Chin
– EMBO Journal
(2012)
336,
428
(DOI: 10.1126/science.1221761)
Designer proteins: applications of genetic code expansion in cell biology.
L Davis, JW Chin
– Nature Reviews Molecular Cell Biology
(2012)
13,
168
(DOI: 10.1038/nrm3286)
Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction.
K Lang, L Davis, J Torres-Kolbus, C Chou, A Deiters, JW Chin
– Nat Chem
(2012)
4,
298
(DOI: 10.1038/nchem.1250)
Reprogramming the genetic code: from triplet to quadruplet codes.
K Wang, WH Schmied, JW Chin
– Angew Chem Int Ed Engl
(2012)
51,
2288
(DOI: 10.1002/anie.201105016)

    Study at Cambridge

    About the University

    Research at Cambridge