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Yusuf Hamied Department of Chemistry

 

Publications by Professor Sir Shankar Balasubramanian FMedSci FRS

G-quadruplex structures are stable and detectable in human genomic DNA
EYN Lam, D Beraldi, D Tannahill, S Balasubramanian
– Nature Communications
(2013)
4,
1796
(DOI: 10.1038/ncomms2792)
Downregulation of androgen receptor transcription by promoter g-quadruplex stabilization as a potential alternative treatment for castrate-resistant prostate cancer.
T Mitchell, A Ramos-Montoya, M Di Antonio, P Murat, S Ohnmacht, M Micco, S Jurmeister, L Fryer, S Balasubramanian, S Neidle, DE Neal
– Biochemistry
(2013)
52,
1429
(DOI: 10.1021/bi301349c)
Genome-wide mapping of FOXM1 binding reveals co-binding with estrogen receptor alpha in breast cancer cells
DA Sanders, CS Ross-Innes, D Beraldi, JS Carroll, S Balasubramanian
– Genome Biology
(2013)
14,
r6
(DOI: 10.1186/gb-2013-14-1-r6)
Quantitative visualization of DNA G-quadruplex structures in human cells.
G Biffi, D Tannahill, J McCafferty, S Balasubramanian
– Nature chemistry
(2013)
5,
182
(DOI: 10.1038/nchem.1548)
An Acetylene‐Bridged 6,8‐Purine Dimer as a Fluorescent Switch‐On Probe for Parallel G‐Quadruplexes
M Nikan, M Di Antonio, K Abecassis, K McLuckie, S Balasubramanian
– Angewandte Chemie (International ed. in English)
(2012)
52,
1428
(DOI: 10.1002/anie.201207075)
An RNA Hairpin to G-Quadruplex Conformational Transition
A Bugaut, P Murat, S Balasubramanian
– Journal of the American Chemical Society
(2012)
134,
19953
(DOI: 10.1021/ja308665g)
The Kinetics and Folding Pathways of Intramolecular G‑Quadruplex Nucleic Acids
AYQ Zhang, S Balasubramanian
– J Am Chem Soc
(2012)
134,
19297
(DOI: 10.1021/ja309851t)
Selective RNA versus DNA G-quadruplex targeting by in situ click chemistry.
M Di Antonio, G Biffi, A Mariani, E-A Raiber, R Rodriguez, S Balasubramanian
– Angew Chem Int Ed Engl
(2012)
51,
11073
(DOI: 10.1002/anie.201206281)
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase.
E-A Raiber, D Beraldi, G Ficz, HE Burgess, MR Branco, P Murat, D Oxley, MJ Booth, W Reik, S Balasubramanian
– Genome biology
(2012)
13,
r69
(DOI: 10.1186/gb-2012-13-8-r69)
An intramolecular G-quadruplex structure is required for binding of telomeric repeat-containing RNA to the telomeric protein TRF2
G Biffi, D Tannahill, S Balasubramanian
– J Am Chem Soc
(2012)
134,
11974
(DOI: 10.1021/ja305734x)
Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells.
S Müller, DA Sanders, M Di Antonio, S Matsis, J-F Riou, R Rodriguez, S Balasubramanian
– Organic & biomolecular chemistry
(2012)
10,
6537
(DOI: 10.1039/c2ob25830g)
Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution
MJ Booth, MR Branco, G Ficz, D Oxley, F Krueger, W Reik, S Balasubramanian
– Science (New York, N.Y.)
(2012)
336,
934
(DOI: 10.1126/science.1220671)
Comparative structural effects of HIV-1 Gag and nucleocapsid proteins in binding to and unwinding of the viral RNA packaging signal.
NM Bell, JC Kenyon, S Balasubramanian, AML Lever
– Biochemistry
(2012)
51,
3162
(DOI: 10.1021/bi2017969)
5'-UTR RNA G-quadruplexes: translation regulation and targeting
A Bugaut, S Balasubramanian
– Nucleic acids research
(2012)
40,
4727
(DOI: 10.1093/nar/gks068)
Experimental approaches to identify cellular G-quadruplex structures and functions.
M Di Antonio, R Rodriguez, S Balasubramanian
– Methods
(2012)
57,
84
(DOI: 10.1016/j.ymeth.2012.01.008)
Demonstration of ligand decoration, and ligand-induced perturbation, of G-quadruplexes in a plasmid using atomic force microscopy.
I Mela, R Kranaster, RM Henderson, S Balasubramanian, JM Edwardson
– Biochemistry
(2012)
51,
578
(DOI: 10.1021/bi201600g)
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
R Rodriguez, KM Miller, JV Forment, CR Bradshaw, M Nikan, S Britton, T Oelschlaegel, B Xhemalce, S Balasubramanian, SP Jackson
– Nature Chemical Biology
(2012)
Synthesis of Bis‐indole Carboxamides as G‐Quadruplex Stabilizing and Inducing Ligands
J Dash, RN Das, N Hegde, GD Pantoş, PS Shirude, S Balasubramanian
– Chemistry A European Journal
(2011)
18,
554
(DOI: 10.1002/chem.201102556)
Decoding genomes at high speed: Implications for science and medicine
S Balasubramanian
– Angewandte Chemie International Edition
(2011)
50,
12406
(DOI: 10.1002/anie.201106707)
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.
P Sarkies, P Murat, LG Phillips, KJ Patel, S Balasubramanian, JE Sale
– Nucleic acids research
(2011)
40,
1485
(DOI: 10.1093/nar/gkr868)

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