Yusuf Hamied Department of Chemistry

Publications by Professor Finian Leeper

Synthetic studies relevant to biosynthetic research on vitamin B12. Part 11. Modification of the east and west building blocks and study of different assembly methods for synthesis of isobacteriochlorins
AR Battersby, MH Block, FJ Leeper, SC Zimmerman
Journal of the Chemical Society, Perkin Transactions 1
(1992)
(doi: 10.1039/P19920002189)
Synthetic studies relevant to biosynthetic research on vitamin B 12 . Part 10. Construction of the east and west building blocks for synthesis of isobacteriochlorins
AR Battersby, MH Block, CJR Fookes, PJ Harrison, GB Henderson, FJ Leeper
Journal of the Chemical Society Perkin Transactions 1
(1992)
(doi: 10.1039/P19920002175)
Synthetic studies on the proposed spiro intermediate for biosynthesis of the natural porphyrins: the stereochemical probe
MA Cassidy, N Crockett, FJ Leeper, AR Battersby
Chemical Communications
(1991)
(doi: 10.1039/c39910000384)
Biosynthesis of vitamin B12: The site of reduction of precorrin-6x
GW Weaver, FJ Leeper, AR Battersby, F Blanche, D Thibaut, L Debussche
Chemical Communications
(1991)
(doi: 10.1039/c39910000976)
The synthesis of a fluorinated analogue of 5-aminolaevulinic acid, a potential inhibitor of porphyrin biosynthesis
FJ Leeper, M Rock
Journal of Fluorine Chemistry
(1991)
51
(doi: 10.1016/s0022-1139(00)80192-x)
Biosynthesis of vitamin B12: Incorporation of (11S)-[11- 2H1-] and (11R)-[11-2H1] porphobilinogen into sirohydrochlorin and 2,7,20-trimethylisobacteriochlorin
GW Weaver, F Blanche, D Thibaut, L Debussche, FJ Leeper, AR Battersby
Chemical Communications
(1990)
(doi: 10.1039/c39900001125)
The effect of strain on the catalytic reactions of bridged thiazolium salts as models of thiamin
FJ Leeper, DHC Smith
Journal of the Chemical Society, Chemical Communications
(1990)
(doi: 10.1039/C39900000961)
BIOSYNTHESIS OF VITAMIN-B12 - STRUCTURE OF PRECORRIN-6X OCTAMETHYL ESTER
D Thibaut, F Blanche, L Debussche, FJ Leeper, AR Battersby
Proceedings of the National Academy of Sciences
(1990)
87
(doi: 10.1073/pnas.87.22.8800)
BIOSYNTHESIS OF PORPHYRINS AND RELATED MACROCYCLES .35. DISCOVERY OF A NOVEL DIPYRROLIC COFACTOR ESSENTIAL FOR THE CATALYTIC ACTION OF HYDROXYMETHYLBILANE SYNTHASE (PORPHOBILINOGEN DEAMINASE)
GJ Hart, AD Miller, U Beifuss, FJ Leeper, AR Battersby
Journal of the Chemical Society, Perkin Transactions 1
(1990)
(doi: 10.1039/p19900001979)
Synthetic studies relevant to biosynthetic research on vitamin B12. Part 9. Synthesis of 20-methyl and 20-cyano isobacteriochlorins
DM Arnott, PJ Harrison, GB Henderson, Z-C Sheng, FJ Leeper, AR Battersby
J CHEM SOC PERK T 1
(1989)
(doi: 10.1039/p19890000265)
BIOSYNTHESIS OF VITAMIN-B12 - SYNTHESIS OF (+-)-[5-C-13]FAKTOR-1 ESTER - DETERMINATION OF THE OXIDATION-STATE OF PRECORRIN-1
RD Brunt, FJ Leeper, I Grgurina, AR Battersby
Chemical Communications
(1989)
(doi: 10.1039/C39890000428)
Stereospecific nucleophilic ring-opening of a deuteriated cyclopropylcarbinol
FJ Leeper, P Padmanabhan
Tetrahedron Letters
(1989)
30
(doi: 10.1016/s0040-4039(01)80570-0)
The biosynthesis of porphyrins, chlorophylls, and vitamin B12
FJ Leeper
Nat Prod Rep
(1989)
6
(doi: 10.1039/np9890600171)
Biosynthesis of porphyrins and related macrocycles. Part 34. Synthesis and properties of S-pyrrolylmethylcysteinyl and ε-N-pyrrolylmethyllysyl peptides
AD Miller, FJ Leeper, AR Battersby
J CHEM SOC PERK T 1
(1989)
(doi: 10.1039/p19890001943)
Syntheses relevant to vitamin B 12 biosynthesis: the malate route to (–)-ring-B imide and synthesis of the 2,7,20-trimethylisobacteriochlorin
WG Whittingham, MK Ellis, P Guerry, GB Henderson, B Müller, DA Taylor, FJ Leeper, AR Battersby
Chemical Communications
(1989)
(doi: 10.1039/c39890001116)
Syntheses relevant to vitamin B12biosynthesis: the glutamate route to (–)-ring-B imide and synthesis of the 2,7,12,20-tetramethylisobacteriochlorin
B Müller, AN Collins, MK Ellis, WG Whittingham, FJ Leeper, AR Battersby
Journal of the Chemical Society Chemical Communications
(1989)
(doi: 10.1039/C39890001119)
Biosynthesis of the pigments of life: Structure and mode of action of a novel enzymatic cofactor
PR Alefounder, GJ Hart, AD Miller, U Beifuss, C Abell, FJ Leeper, AR Battersby
Bioorganic Chemistry
(1989)
17
(doi: 10.1016/0045-2068(89)90013-8)
Biosynthesis of vitamin B12: when is the 12β-methyl group of the vitamin generated by acetate decarboxylation?
F Blanche, S Handa, D Thibaut, CL Gibson, FJ Leeper, AR Battersby
Journal of the Chemical Society Chemical Transactions
(1988)
(doi: 10.1039/c39880001117)
CHIRALLY TRITIATED AND DEUTERIATED COMPOUNDS IN STUDIES OF BIOSYNTHESIS
FJ LEEPER, AR BATTERSBY
APPL RADIAT ISOTOPES
(1988)
39
Biosynthesis of porphyrins and related macrocycles. Part 30. Synthesis of the macrocycle of the spiro system proposed as an intermediate generated by cosynthetase
WM Stark, MG Baker, FJ Leeper, PR Raithby, AR Battersby
Journal of the Chemical Society, Perkin Transactions 1
(1988)
(doi: 10.1039/p19880001187)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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