Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate
S Lüdtke, P Neumann, KM Erixon, F Leeper, R Kluger, R Ficner, K Tittmann
Nature Chemistry
(2013)
5
Metabolic glycan imaging by isonitrile-tetrazine click chemistry
S Stairs, AA Neves, H Stöckmann, YA Wainman, H Ireland-Zecchini, KM Brindle, FJ Leeper
Chembiochem
(2013)
14
Imaging Cell Surface Glycosylation in Vivo Using “Double Click” Chemistry
AA Neves, H Stöckmann, YA Wainman, JC-H Kuo, S Fawcett, FJ Leeper, KM Brindle
Bioconjug Chem
(2013)
24
Synthesis of 3,4-Disubstituted Pyrroles. A Review
FJ Leeper, JM Kelly
Organic Preparations and Procedures International
(2013)
45
Identification and characterisation of the gene cluster for the anti-MRSA antibiotic bottromycin: expanding the biosynthetic diversity of ribosomal peptides
WJK Crone, FJ Leeper, AW Truman
Chemical Science
(2012)
3
α-Hydroxy-β-keto acid rearrangement–decarboxylation: impact on thiamine diphosphate-dependent enzymatic transformations
M Beigi, S Loschonsky, P Lehwald, V Brecht, SLA Andrade, FJ Leeper, W Hummel, M Müller
Org Biomol Chem
(2012)
11
Bacterial Biosynthetic Gene Clusters Encoding the Anti-cancer Haterumalide Class of Molecules BIOGENESIS OF THE BROAD SPECTRUM ANTIFUNGAL AND ANTI-OOMYCETE COMPOUND, OOCYDIN A
MA Matilla, H Stöckmann, FJ Leeper, GPC Salmond
J Biol Chem
(2012)
287
Probing riboswitch– ligand interactions using thiamine pyrophosphate analogues
L Chen, E Cressina, N Dixon, K Erixon, K Agyei-Owusu, J Micklefield, AG Smith, C Abell, FJ Leeper
Organic & Biomolecular Chemistry
(2012)
10
Synthesis of 3,4-fused cycloalkanopyrroles by 1,3-dipolar cycloaddition
JM Kelly, FJ Leeper
Tetrahedron Letters
(2012)
53
Characterisation of PigC and HapC, the prodigiosin synthetases from Serratia sp. and Hahella chejuensis with potential for biocatalytic production of anticancer agents
SR Chawrai, NR Williamson, T Mahendiran, GPC Salmond, FJ Leeper
Chemical Science
(2012)
3
Biosynthesis of Vitamin B12\
FJ Leeper, MJ Warren, JM Kelly, AD Lawrence
(2012)
25
Copper-free click--a promising tool for pre-targeted PET imaging.
HL Evans, RL Slade, L Carroll, G Smith, Q-D Nguyen, L Iddon, N Kamaly, H Stöckmann, FJ Leeper, EO Aboagye, AC Spivey
Chemical communications (Cambridge, England)
(2011)
48
Exploring isonitrile-based click chemistry for ligation with biomolecules.
H Stöckmann, AA Neves, S Stairs, KM Brindle, FJ Leeper
Organic & Biomolecular Chemistry
(2011)
9
(E,E)-1,5-Cyclooctadiene: a small and fast click-chemistry multitalent
H Stöckmann, AA Neves, HA Day, S Stairs, KM Brindle, FJ Leeper
Chemical Communications
(2011)
47
Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells.
H Stöckmann, AA Neves, S Stairs, H Ireland-Zecchini, KM Brindle, FJ Leeper
Chem Sci
(2011)
2
Imaging sialylated tumor cell glycans in vivo
AA Neves, H Stöckmann, RR Harmston, HJ Pryor, IS Alam, H Ireland-Zecchini, DY Lewis, SK Lyons, FJ Leeper, KM Brindle
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
(2011)
25
Identification of novel ligands for thiamine pyrophosphate (TPP) riboswitches.
E Cressina, L Chen, M Moulin, FJ Leeper, C Abell, AG Smith
Biochemical Society Transactions
(2011)
39
In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines.
M Tosin, Y Demydchuk, JS Parascandolo, CB Per, FJ Leeper, PF Leadlay
Chem Commun (Camb)
(2011)
47
Fragment screening against the thiamine pyrophosphate riboswitch thiM
E Cressina, L Chen, C Abell, FJ Leeper, AG Smith
Chemical Science
(2011)
2
Prodiginines and Their Potential Utility as Proapoptotic Anticancer Agents
NR Williamson, S Chawrai, FJ Leeper, GPC Salmond
(2010)