Inhibition of pyruvate decarboxylase from Z-mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics
KM Erixon, CL Dabalos, FJ Leeper
– Chem Commun (Camb)
(2006)
960
(DOI: 10.1039/b615861g)
Disruption of the copper efflux pump (CopA) of Serratia marcescens ATCC 274 pleiotropically affects copper sensitivity and production of the tripyrrole secondary metabolite, prodigiosin
NR Williamson, HT Simonsen, AKP Harris, FJ Leeper, GPC Salmond
– J Ind Microbiol Biotechnol
(2006)
33,
151
(DOI: 10.1007/s10295-005-0040-9)
The biosynthesis and regulation of bacterial prodiginines
NR Williamson, PC Fineran, FJ Leeper, GPC Salmond
– Nat Rev Microbiol
(2006)
4,
887
(DOI: 10.1038/nrmicro1531)
Studies on thiamine diphosphate-dependent enzymes.
FJ Leeper, D Hawksley, S Mann, C Perez Melero, MDH Wood
– Biochemical Society Transactions
(2005)
33,
772
(DOI: 10.1042/bst0330772)
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: Identification of a novel 2-methyl-3-n-amyl-pyrroie (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces
NR Williamson, HT Simonsen, RAA Ahmed, G Goldet, H Slater, L Woodley, FJ Leeper, GPC Salmond
– Mol Microbiol
(2005)
56,
971
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species- and strain-dependent genome context variation
AKP Harris, NR Williamson, H Slater, A Cox, S Abbasi, I Foulds, HT Simonsen, FJ Leeper, GPC Salmond
– Microbiology (Reading)
(2004)
150,
3547
(DOI: 10.1099/mic.0.27222-0)
The role of His113 and His114 in pyruvate decarboxylase from Zymomonas mobilis.
G Schenk, FJ Leeper, R England, PF Nixon, RG Duggleby
– European Journal of Biochemistry
(2004)
248,
63
Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate
S Mann, C Perez Melero, D Hawksley, FJ Leeper
– Organic & biomolecular chemistry
(2004)
2,
1732
(DOI: 10.1039/b403619k)
Vitamin B12: How the Problem of Its Biosynthesis Was Solved
F BLANCHE, B CAMERON, J CROUZET, L DEBUSSCHE, D THIBAUT, M VUILHORGNE, FJ LEEPER, AR BATTERSBY
– Angewandte Chemie International Edition
(2003)
34,
383
(DOI: 10.1002/anie.199503831)
Stereochemistry and mechanism of the conversion of 5-aminolaevulinic acid into porphobilinogen catalysed by porphobilinogen synthase.
CE Goodwin, FJ Leeper
– Organic & biomolecular chemistry
(2003)
1,
1443
(DOI: 10.1039/b302509h)
A new synthesis of porphobilinogen analogues, inhibitors of hydroxymethylbilane synthase
R Ahmed, FJ Leeper
– Organic and Biomolecular Chemistry
(2002)
1,
21
(DOI: 10.1039/b209613g)
Stereoisomers of Tetrahydrothiamin Pyrophosphate, Potent Inhibitors of the Pyruvate Dehydrogenase Multienzyme Complex from Escherichia coli
PN Lowe, FJ Leeper, RN Perham
– Biochemistry
(2002)
22,
150
(DOI: 10.1021/bi00270a022)
Biosynthesis of the pigments of life: mechanistic studies on the conversion of porphobilinogen to uroporphyrinogen III
AR BATTERSBY, FJ LEEPER
– Chemical Reviews
(2002)
90,
1261
(DOI: 10.1021/cr00105a009)
Stereochemical studies of porphobilinogen synthase using deuteriated 5-aminolevulinic acid.
CE Goodwin, FJ Leeper
– ABSTR PAP AM CHEM S
(2002)
223,
B208
Kinetics of the thiazolium ion-catalyzed benzoin condensation.
MJ White, FJ Leeper
– The Journal of organic chemistry
(2001)
66,
5124
(DOI: 10.1021/jo010244h)
Synthesis of 3-deazathiamine
D Hawksley, DA Griffin, FJ Leeper
– Journal of the Chemical Society. Perkin Transactions 1
(2001)
144
(DOI: 10.1039/b006962k)
Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids. Topics in Current Chemistry. Vol. 209 Edited by Finian J. Leeper (University of Cambridge) and John C. Vederas (University of Alberta). Springer-Verlag: Berlin, Heidelberg, New York. 2000. viii + 247 pp. $159.00. ISBN 3-540-66573-0.
AI Scott
– Journal of the American Chemical Society
(2000)
122,
11756
(DOI: 10.1021/ja0047626)
Biosynthesis of porphyrins and related macrocycles. Part 51.I>2 Proof that a reductive step occurs during the biosynthesis of vitamin B12 by the microaerophilic organism, Propionibacterium shevmann
K Ichinose, M Kodera, FJ Leeper, AR Battersby
– JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
(1999)
879
(DOI: 10.1039/a809858a)
Biosynthesis of vitamin B<sub>12</sub>
AR Battersby, FJ Leeper
– BIOSYNTHESIS
(1998)
195,
143
(DOI: 10.1007/3-540-69542-7_4)