Inhibition of pyruvate decarboxylase from Z. mobilis by novel analogues of thiamine pyrophosphate: investigating pyrophosphate mimics.
KM Erixon, CL Dabalos, FJ Leeper
Chem. Commun.
(2006)
The biosynthesis and regulation of bacterial prodiginines.
NR Williamson, PC Fineran, FJ Leeper, GPC Salmond
Nature Reviews Microbiology
(2006)
4
Disruption of the copper A lux pump (CopA) of Serratia marcescens ATCC 274 pleiotropically affects copper sensitivity and production of the tripyrrole secondary metabolite, prodigiosin
NR Williamson, HT Simonsen, AKP Harris, FJ Leeper, GPC Salmond
Journal of Industrial Microbiology & Biotechnology
(2006)
33
Studies on thiamine diphosphate-dependent enzymes
FJ Leeper, D Hawksley, S Mann, C Perez Melero, MDH Wood
Biochemical Society Transactions
(2005)
33
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces
NR Williamson, HT Simonsen, RAA Ahmed, G Goldet, H Slater, L Woodley, FJ Leeper, GPC Salmond
Molecular Microbiology
(2005)
56
The Serratia gene cluster encoding biosynthesis of the red antibiotic, prodigiosin, shows species-and strain-dependent genome context variation
AKP Harris, NR Williamson, H Slater, A Cox, S Abbasi, I Foulds, HT Simonsen, FJ Leeper, GPC Salmond
Microbiology (Reading)
(2004)
150
The Role of His113 and His114 in Pyruvate Decarboxylase from Zymomonas Mobilis
G Schenk, FJ Leeper, R England, PF Nixon, RG Duggleby
The FEBS Journal
(2004)
248
Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate.
S Mann, C Perez Melero, D Hawksley, FJ Leeper
Organic & biomolecular chemistry
(2004)
2
Vitamin B12: How the Problem of Its Biosynthesis Was Solved
F Blanche, B Cameron, J Crouzet, L Debussche, D Thibaut, M Vuilhorgne, FJ Leeper, AR Battersby
Angewandte Chemie International Edition in English
(2003)
34
Stereochemistry and mechanism of the conversion of 5-aminolaevulinic acid into porphobilinogen catalysed by porphobilinogen synthase
CE Goodwin, FJ Leeper
Org Biomol Chem
(2003)
1
A new synthesis of porphobilinogen analogues, inhibitors of hydroxymethylbilane synthase.
R Ahmed, FJ Leeper
Organic and Biomolecular Chemistry
(2002)
1
Stereoisomers of Tetrahydrothiamin Pyrophosphate, Potent Inhibitors of the Pyruvate Dehydrogenase Multienzyme Complex from Escherichia coli
PN Lowe, FJ Leeper, RN Perham
Biochemistry
(2002)
22
Biosynthesis of the pigments of life: mechanistic studies on the conversion of porphobilinogen to uroporphyrinogen III
AR Battersby, FJ Leeper
Chemical Reviews
(2002)
90
Stereochemical studies of porphobilinogen synthase using deuteriated 5-aminolevulinic acid.
CE Goodwin, FJ Leeper
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2002)
223
Kinetics of the thiazolium ion-catalyzed benzoin condensation.
MJ White, FJ Leeper
The Journal of Organic Chemistry
(2001)
66
Synthesis of 3-deazathiamine
D Hawksley, DA Griffin, FJ Leeper
Journal of the Chemical Society Perkin Transactions 1
(2001)
Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids. Topics in Current Chemistry. Vol. 209 Edited by Finian J. Leeper (University of Cambridge) and John C. Vederas (University of Alberta). Springer-Verlag: Berlin, Heidelberg, New York. 2000. viii + 247 pp. $159.00. ISBN 3-540-66573-0.
AI Scott
Journal of the American Chemical Society
(2000)
122
Biosynthesis
(2000)
209
Biosynthesis of porphyrins and related macrocycles. Part 51.1,2 Proof that a reductive step occurs during the biosynthesis of vitamin B12 by the microaerophilic organism, Propionibacterium shermanii
K Ichinose, M Kodera, FJ Leeper, AR Battersby
J CHEM SOC PERK T 1
(1999)
Biosynthesis of Vitamin B12
AR Battersby, FJ Leeper
BIOSYNTHESIS
(1998)
195