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Yusuf Hamied Department of Chemistry

 

Publications by Professor Finian Leeper

Imaging sialylated tumor cell glycans <i>in vivo</i>
AA Neves, H Stöckmann, RR Harmston, HJ Pryor, IS Alam, H Ireland-Zecchini, DY Lewis, SK Lyons, FJ Leeper, KM Brindle
– FASEB Journal
(2011)
25,
2528
(DOI: 10.1096/fj.10-178590)
Identification of novel ligands for thiamine pyrophosphate (TPP) riboswitches.
E Cressina, L Chen, M Moulin, FJ Leeper, C Abell, AG Smith
– Biochemical Society Transactions
(2011)
39,
652
(DOI: 10.1042/BST0390652)
In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines
M Tosin, Y Demydchuk, JS Parascandolo, CB Per, FJ Leeper, PF Leadlay
– Chem Commun (Camb)
(2011)
47,
3460
(DOI: 10.1039/c0cc05077f)
Fragment screening against the thiamine pyrophosphate riboswitch <i>thiM</i>
E Cressina, LH Chen, C Abell, FJ Leeper, AG Smith
– Chem. Sci.
(2011)
2,
157
(DOI: 10.1039/c0sc00406e)
Prodiginines and Their Potential Utility as Proapoptotic Anticancer Agents
NR Williamson, S Chawrai, FJ Leeper, GPC Salmond
(2010)
333
(DOI: 10.1002/9780470626528.ch15)
A Fragment-Based Approach to Identifying Ligands for Riboswitches
L Chen, E Cressina, FJ Leeper, AG Smith, C Abell
– ACS Chem Biol
(2010)
5,
355
(DOI: 10.1021/cb9003139)
Structural Insights into the Prereaction State of Pyruvate Decarboxylase from <i>Zymomonas mobilis</i>
X-Y Pei, KM Erixon, BF Luisi, FJ Leeper
– Biochemistry
(2010)
49,
1727
(DOI: 10.1021/bi901864j)
Thiamin diphosphate in biological chemistry: analogues of thiamin diphosphate in studies of enzymes and riboswitches.
K Agyei-Owusu, FJ Leeper
– FEBS Journal
(2009)
276,
2905
(DOI: 10.1111/j.1742-4658.2009.07018.x)
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex.
XY Pei, CM Titman, RAW Frank, FJ Leeper, BF Luisi
– Structure
(2008)
16,
1860
(DOI: 10.1016/j.str.2008.10.009)
Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold.
KM Erixon, CL Dabalos, FJ Leeper
– Organic &amp; Biomolecular Chemistry
(2008)
6,
3561
(DOI: 10.1039/b806580b)
Biomimetic Syntheses of Phenols from Polyketones
GE Evans, MJ Garson, DA Griffin, FJ Leeper, J Stauton
– Ciba Foundation symposium
(2008)
53,
131
(DOI: 10.1002/9780470720349.ch9)
Chemoenzymatic synthesis of prodigiosin analogues - Exploring the substrate specificity of PigC
SR Chawrai, NR Williamson, GPC Salmond, FJ Leeper
– Chemical communications (Cambridge, England)
(2008)
1862
(DOI: 10.1039/b719353j)
Anticancer and immunosuppressive properties of bacterial prodiginines.
NR Williamson, PC Fineran, T Gristwood, SR Chawrai, FJ Leeper, GPC Salmond
– Future Microbiol
(2007)
2,
605
(DOI: 10.2217/17460913.2.6.605)
Structure of the branched-chain keto acid decarboxylase (KdcA) from Lactococcus lactis provides insights into the structural basis for the chemoselective and enantioselective carboligation reaction
CL Berthold, D Gocke, MD Wood, FJ Leeper, M Pohl, G Schneider
– Acta Crystallographica Section D: Biological Crystallography
(2007)
63,
1217
(DOI: 10.1107/s0907444907050433)
Editorial: Vitamins and cofactors - Chemistry, biochemistry and biology
FJ Leeper, AG Smith
– Natural Product Reports
(2007)
24,
923
(DOI: 10.1039/b712088p)
The evidence for a spirocyclic intermediate in the formation of uroporphyrinogen III by cosynthase.
FJ Leeper
– Ciba Found Symp
(2007)
180,
111
(DOI: 10.1002/9780470514535.ch7)
Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase.
W Versées, S Spaepen, MDH Wood, FJ Leeper, J Vanderleyden, J Steyaert
– The Journal of biological chemistry
(2007)
282,
35269
(DOI: 10.1074/jbc.m706048200)
Editorial: vitamins and cofactors - chemistry, biochemistry and biology.
FJ Leeper, AG Smith
– Natural Product Reports
(2007)
24,
923
(DOI: 10.1039/b712088p)
Crystallographic snapshots of oxalyl-CoA decarboxylase give insights into catalysis by nonoxidative ThDP-dependent decarboxylases.
CL Berthold, CG Toyota, P Moussatche, MD Wood, F Leeper, NGJ Richards, Y Lindqvist
– Structure
(2007)
15,
853
(DOI: 10.1016/j.str.2007.06.001)
Structure, mechanism and catalytic duality of thiamine-dependent enzymes.
RAW Frank, FJ Leeper, BF Luisi
– Cellular and Molecular Life Sciences
(2007)
64,
892
(DOI: 10.1007/s00018-007-6423-5)

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