Biosynthesis, Polyketides and Vitamins
(1998)
195
Investigation of the mechanistic functions of residues HIS113 and HIS114 in pyruvate decarboxylase from Zymomonas mobilis: A proposed model in the binding of the substrate pyruvate
G Schenk, FJ Leeper, R England, PF Nixon, RG Duggleby
FASEB Journal
(1997)
11
Haem d(1): stereoselective synthesis of the macrocycle to establish its absolute configuration as 2R,7R
J Micklefield, M Beckmann, RL Mackman, MH Block, FJ Leeper, AR Battersby
Journal of the Chemical Society Perkin Transactions 1
(1997)
Haem d 1 : stereoselective synthesis of the reduced form of its parent macrocycle using the original coupling strategy
CJ Aucken, FJ Leeper, AR Battersby
J CHEM SOC PERK T 1
(1997)
Haem d1: development of a new coupling procedure leading to the synthesis of isobacteriochlorins 1
RL Mackman, J Micklefield, MH Block, FJ Leeper, AR Battersby
Journal of the Chemical Society Perkin Transactions 1
(1997)
Synthesis of and asymmetric induction by chiral bicyclic thiazolium salts
RL Knight, FJ Leeper
Tetrahedron Letters
(1997)
38
Synthesis of and asymmetric induction by chiral polycyclic thiazolium salts
AU Gerhard, FJ Leeper
Tetrahedron Letters
(1997)
38
Synthetic studies relevant to biosynthetic research on vitamin B12. Part 12. Modification of the periphery of chlorins and isobacteriochlorins
JJ De Voss, FJ Leeper, AR Battersby
Journal of the Chemical Society Perkin Transactions 1
(1997)
Synthesis of tetrahydroquinolines, hexahydrobenzoindolizines and an aryl phosphonate linker for the generation of catalytic antibodies
C González-Bello, C Abell, FJ Leeper
J CHEM SOC PERK T 1
(1997)
Interaction of analogues of porphobilinogen with porphobilinogen deaminase
FJ Leeper, M Rock
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
(1996)
Synthesis of analogues of porphobilinogen
FJ Leeper, M Rock, D Appleton
Journal of the Chemical Society Perkin Transactions 1
(1996)
Biosynthesis of porphyrins and related macrocycles .44. Synthetic and stereochemical studies on the proposed spiro intermediate for biosynthesis of the natural porphyrins
MA Cassidy, N Crockett, FJ Leeper, AR Battersby
Journal of the Chemical Society Perkin Transactions 1
(1996)
Biosynthesis of porphyrins and related macrocycles .45. Determination by a novel X-ray method of the absolute configuration of the spiro lactam which inhibits uroporphyrinogen III synthase (cosynthetase)
AC Spivey, A Capretta, CS Frampton, FJ Leeper, AR Battersby
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
(1996)
Deuterium isotope effects on porphobilinogen synthesis catalysed by 5-aminolaevulinic acid dehydratase
D Appleton, FJ Leeper
Bioorganic & Medicinal Chemistry Letters
(1996)
6
Mechanism-based inhibition of 5-aminolaevulinic acid dehydratase from Bacillus subtilis by the 3-thia analogue of the substrate
D Appleton, FJ Leeper
Chemical Communications
(1996)
Stereochemical studies on the proposed spiro intermediate for the biosynthesis of the natural porphyrins: determination by a novel X-ray method of the absolute configuration of the spirolactam which inhibits cosynthetase
AC Spivey, A Capretta, CS Frampton, FJ Leeper, AR Battersby
Journal of the Chemical Society Chemical Communications
(1995)
Stereocontrolled syntheses of polyhydroxy indolizidines, including 8a-epi-, 6,8a-diepi- and 1,6-diepi-castanospermine, starting from malic acid
FJ Leeper, S Howard
Tetrahedron Letters
(1995)
36
Synthesis of bridged thiazolium salts as models for thiamin
FJ Leeper, DHC Smith
Journal of the Chemical Society, Perkin Transactions 1
(1995)
Biosynthesis of porphyrins and related macrocycles, Part 43. Isolation and characterization of intermediates of coenzyme B12 biosynthesis, a cobyrinic acid triamide, the a,c-diamide and their Co-(5'-deoxy-5'-adenosyl) derivatives, from Propionibacterium shermanii.
F Kiuchi, FJ Leeper, AR Battersby
Cell Chemical Biology
(1995)
2
Bridged thiazolium salts as models for thiamin: NMR, crystallographic and molecular mechanics studies
FJ Leeper, DHC Smith, MJ Doyle, PR Raithby
J CHEM SOC PERK T 2
(1995)