Yusuf Hamied Department of Chemistry

Publications by Professor Finian Leeper

18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography
F Bulat, F Hesse, D-E Hu, S Ros, W-H Connor, B Xie, B Attili, D Soloviev, F Aigbirhio, F Leeper, K Brindle, A Neves
EJNMMI Research
(2020)
(doi: 10.1186/s13550-020-00738-7)
Development of targeted imaging agents for detecting tumour cell death
F Bulat, A Neves, F Hesse, D-E Hu, F Aigbirhio, F Leeper, K Brindle
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
(2020)
63
Unexpected enzyme-catalysed [4+2] cycloaddition and rearrangement in polyether antibiotic biosynthesis.
R Little, FCR Paiva, R Jenkins, H Hong, Y Sun, Y Demydchuk, M Samborskyy, M Tosin, FJ Leeper, MVB Dias, PF Leadlay
Nat Catal
(2019)
2
(doi: 10.1038/s41929-019-0351-2)
Substrate Flexibility of the Flavin-Dependent Dihydropyrrole Oxidases PigB and HapB Involved in Antibiotic Prodigiosin Biosynthesis
F Leeper, M Couturier, HD Bhalara, SR Chawrai, R Monson, NR Williamson, G Salmond
ChemBioChem
(2019)
21
(doi: 10.1002/cbic.201900424)
Development of targeted imaging agents for detecting tumour cell death
F Bulat, A Neves, D Soloviev, B Xie, F Aigbirhio, F Leeper, K Brindle
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
(2018)
61
Structure of the Fundamental Lipopeptide Surfactin at the Air/Water Interface Investigated by Sum Frequency Generation Spectroscopy
SA Goussous, MTL Casford, AC Murphy, GPC Salmond, FJ Leeper, PB Davies
Journal of Physical Chemistry B
(2017)
121
(doi: 10.1021/acs.jpcb.7b03476)
Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics.
WJK Crone, NM Vior, J Santos-Aberturas, LG Schmitz, FJ Leeper, AW Truman
Angewandte Chemie (International ed. in English)
(2016)
55
(doi: 10.1002/anie.201604304)
Rücktitelbild: Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging (Angew. Chem. 4/2016)
AA Neves, YA Wainman, A Wright, MI Kettunen, TB Rodrigues, S McGuire, D Hu, F Bulat, SG Crich, H Stöckmann, FJ Leeper, KM Brindle
Angewandte Chemie
(2015)
128
(doi: 10.1002/ange.201511259)
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging
AA Neves, YA Wainman, A Wright, MI Kettunen, TB Rodrigues, S McGuire, D Hu, F Bulat, SG Crich, H Stöckmann, FJ Leeper, KM Brindle
Angewandte Chemie International Ed in English
(2015)
55
(doi: 10.1002/anie.201511259)
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging.
AA Neves, YA Wainman, A Wright, MI Kettunen, TB Rodrigues, S McGuire, D-E Hu, F Bulat, S Geninatti Crich, H Stöckmann, FJ Leeper, KM Brindle
Angewandte Chemie (International ed. in English)
(2015)
55
(doi: 10.1002/anie.201509858)
Imaging Glycosylation In Vivo by Metabolic Labeling and Magnetic Resonance Imaging
AA Neves, YA Wainman, A Wright, MI Kettunen, TB Rodrigues, S McGuire, D-E Hu, F Bulat, S Geninatti Crich, H Stöckmann, FJ Leeper, KM Brindle
Angew Chem Weinheim Bergstr Ger
(2015)
128
(doi: 10.1002/ange.201509858)
Validation of a homology model of Mycobacterium tuberculosis DXS: rationalization of observed activities of thiamine derivatives as potent inhibitors of two orthologues of DXS
T Masini, B Lacy, L Monjas, D Hawksley, AR de Voogd, B Illarionov, A Iqbal, FJ Leeper, M Fischer, M Kontoyianni, AKH Hirsch
Organic & Biomolecular Chemistry
(2015)
13
(doi: 10.1039/c5ob01666e)
Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq.
MA Matilla, FJ Leeper, GPC Salmond
Environ Microbiol
(2015)
17
(doi: 10.1111/1462-2920.12839)
Asymmetric Stetter reactions catalyzed by thiamine diphosphate-dependent enzymes
E Kasparyan, M Richter, C Dresen, LS Walter, G Fuchs, FJ Leeper, T Wacker, SLA Andrade, G Kolter, M Pohl, M Müller
Applied Microbiology and Biotechnology
(2014)
98
(doi: 10.1007/s00253-014-5850-0)
Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate.
A Iqbal, E-H Sahraoui, FJ Leeper
Beilstein J Org Chem
(2014)
10
(doi: 10.3762/bjoc.10.270)
Asymmetric Stetter reactions catalyzed by thiamine diphosphate-dependent enzymes
E Kasparyan, M Richter, C Dresen, LS Walter, G Fuchs, FJ Leeper, T Wacker, SLA Andrade, G Kolter, M Pohl, M Müller
Applied microbiology and biotechnology
(2014)
98
(doi: 10.1007/s00253-014-5850-0)
Specificity and promiscuity at the branch point in gentamicin biosynthesis
J Guo, F Huang, C Huang, X Duan, X Jian, F Leeper, Z Deng, PF Leadlay, Y Sun
Chemistry and Biology
(2014)
21
(doi: 10.1016/j.chembiol.2014.03.005)
Specificity and promiscuity at the branch point in gentamicin biosynthesis.
J Guo, F Huang, C Huang, X Duan, X Jian, F Leeper, Z Deng, PF Leadlay, Y Sun
Chemistry & Biology
(2014)
21
(doi: 10.1016/j.chembiol.2014.03.005)
Diazo group as a new chemical reporter for bioorthogonal labelling of biomolecules
L Josa-Culleré, YA Wainman, KM Brindle, FJ Leeper
RSC Advances
(2014)
4
(doi: 10.1039/c4ra08861a)
Structure of a eukaryotic thiaminase I
CA Kreinbring, SP Remillard, P Hubbard, HR Brodkin, FJ Leeper, D Hawksley, EY Lai, C Fulton, GA Petsko, D Ringe
Proc Natl Acad Sci U S A
(2013)
111
(doi: 10.1073/pnas.1315882110)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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