University Associate Professor
Rosana is the Professor of Computational and Molecular Biophysics at the Departments of Chemistry and Genetics, and a Winton Advanced Research Fellow in the Department of Physics. Her group develops multiscale modelling approaches to investigate the physicochemical driving forces that govern DNA packaging inside cells, membraneless compartamentalization via liquid-liquid phase behaviour of biomolecules (proteins, nucleic acids, and chromatin), chromatin structure, epigenetic phenomena, and the relationship between the structure of the genome and gene expression regulation.
Professor Collepardo discusses her research
Publications
Analysis of long-range contacts across cell types outlines a core sequence determinant of 3D genome organisation
(2025)
(doi: 10.1101/2025.03.16.643527)
Molecular insights on the mechanism of α 1 -antitrypsin condensate formation and maturation
(2025)
(doi: 10.1101/2025.03.11.642656)
Linker histone H1 functions as a liquid-like glue to organize chromatin in living human cells
(2025)
(doi: 10.1101/2025.03.05.641622)
Compositional control of ageing kinetics in TDP-43 condensates
(2025)
(doi: 10.1101/2025.02.21.639421)
Cold-induced nucleosome dynamics linked to silencing of Arabidopsis FLC
(2025)
(doi: 10.1101/2025.02.17.638618)
Decoding phase separation of prion-like domains through data-driven scaling laws
Elife
(2025)
13
RP99068
(doi: 10.7554/eLife.99068)
Chemically Informed Coarse-Graining of Electrostatic Forces in Charge-Rich Biomolecular Condensates
ACS Central Science
(2025)
11
302
(doi: 10.1021/acscentsci.4c01617)
Benchmarking residue-resolution protein coarse-grained models for simulations of biomolecular condensates
PLOS Computational Biology
(2025)
21
e1012737
(doi: 10.1371/journal.pcbi.1012737)
Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws
(2025)
(doi: 10.7554/elife.99068.2)
Nucleosome Spacing Can Fine-Tune Higher Order Chromatin Assembly.
(2024)
(doi: 10.1101/2024.12.23.627571)
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