University Professor
Rosana is the Professor of Computational and Molecular Biophysics at the Departments of Chemistry and Genetics, and a Winton Advanced Research Fellow in the Department of Physics. Her group develops multiscale modelling approaches to investigate the physicochemical driving forces that govern DNA packaging inside cells, membraneless compartamentalization via liquid-liquid phase behaviour of biomolecules (proteins, nucleic acids, and chromatin), chromatin structure, epigenetic phenomena, and the relationship between the structure of the genome and gene expression regulation.
Professor Collepardo discusses her research
Publications
Electrostatic control of chromatin compaction safeguards against apoptotic DNA release.
The EMBO Journal
(2026)
1
(doi: 10.1038/s44318-026-00932-8)
RNA Synthesis
and Degradation Regulate Biomolecular
Condensates through Nonequilibrium Feedback
ACS Central Science
(2026)
(doi: 10.1021/acscentsci.6c00933)
PepSpace: An Automated, Physics-Driven Directed Evolution Platform for the De Novo Design of Specific Peptide Binders and Condensate Modulators
(2026)
(doi: 10.64898/2026.09.18.752684)
Molecular simulations of chromatin-associated biomolecular condensates.
Curr Opin Struct Biol
(2026)
101
103378
(doi: 10.1016/j.sbi.2026.103378)
Capsid stabilization reprograms the nuclear fate of the HIV genome.
Sci Adv
(2026)
12
eaef9469
(doi: 10.1126/sciadv.aef9469)
Compositional control of FUS condensate ageing through aggregation-prone interaction networks
(2026)
(doi: 10.64898/2026.07.31.741205)
A Spectrum of Free Energy Landscape Topologies Encodes Chromatin Polymorphism and Phase Separation
(2026)
(doi: 10.64898/2026.06.19.733383)
hexABC seeking the physical code of DNA
Nature Communications
(2026)
17
8169
(doi: 10.1038/s41467-026-74390-5)
Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation
Nature Communications
(2026)
(doi: 10.1101/2025.11.17.688899)
Single-molecule nucleosome spacing coordinates chromatin fiber interactions.
(2026)
(doi: 10.64898/2026.06.02.729033)
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