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Yusuf Hamied Department of Chemistry

 

Dr Jenny Zhang

University Assistant Professor

"Life is nothing but an electron looking for a place to rest"  
- Albert Szent-Györgyi (Nobel Laureate in Physiology 1937)

Current research

My team's goal is to develop smart bio-hybrid approaches that can help to probe or re-wire the bioenergetics of living systems. These can serve as platforms to launch new biotechnologies to address a range of societal needs, including for renewable energy generation, carbon recycling, precision farming, environmental sensing, and treating pathogenic biofilms. Currently, we are focused on understanding and re-wiring photosynthesis towards sustainable energy conversion. We work at the intersection of many disciplines, including physics, synthetic biology, chemical biology, engineering and material science; but at the heart of our work is electrochemistry.

Please see our website for more info: https://www.ch.cam.ac.uk/group/zhang

**PhD positions available. Contact Jenny and attach your CV to enquire.**

Jenny completed her PhD in bioinorganic chemistry at the University of Sydney, Australia, with a brief stint at the Hebrew University of Jerusalem. During this time, she developed redox active platinum-based anti-cancer agents and studied their biodistribtion and metabolism within tumour models. Following this, she was awarded a Marie Curie Incoming International Fellowship at the University of Cambridge to explore how biocatalysts can be exploited to generate solar fuels. In particular, she worked on developing strategies to re-wire complex enzymes, such as the water-oxidation enzyme photosystem II, to electrodes/semiconductors/other proteins in an emerging field known as 'semi-artificial photosynthesis'. She has since been awarded a BBSRC David Phillips Fellowship, followed by appointment to Assistant Professor in Materials Chemistry at the Yusuf Hamied Department of Chemistry. Here, she takes on the re-wiring of photosynthesis to another level of complexity - in living cells! She was awarded the RSC Felix Franks Biotechnology Medal and the L'Oreal UNESCO Sustainable Development award for Women in Science. Most recently, she won the Outstanding Supervisor Award 2024 in her department.

Watch Dr Zhang discuss her research

Publications

Dissecting a biological electron transport network with electrochemistry
JM Lawrence, RM Egan, LT Wey, K Bali, X Chen, D Kosmützky, M Eyres, L Nan, MH Wood, MM Nowaczyk, CJ Howe, JZ Zhang
(2025)
(doi: 10.1101/2025.03.18.643929)
Harvesting photocurrents from cyanobacteria and algae
EI Wroe, RM Egan, SJ Willyam, L Shang, JZ Zhang
– Current Opinion in Electrochemistry
(2024)
46,
101535
(doi: 10.1016/j.coelec.2024.101535)
Fourfold increase in photocurrent generation of Synechocystis sp. PCC 6803 by exopolysaccharide deprivation
LT Wey, EI Wroe, V Sadilek, L Shang, X Chen, JZ Zhang, CJ Howe
– Electrochimica Acta
(2024)
497,
144555
(doi: 10.1016/j.electacta.2024.144555)
Rewiring photosynthetic electron transport chains for solar energy conversion
JM Lawrence, RM Egan, T Hoefer, A Scarampi, L Shang, CJ Howe, JZ Zhang
– Nature Reviews Bioengineering
(2023)
1,
887
(doi: 10.1038/s44222-023-00093-x)
Photosynthesis re-wired on the pico-second timescale.
TK Baikie, LT Wey, JM Lawrence, H Medipally, E Reisner, MM Nowaczyk, RH Friend, CJ Howe, C Schnedermann, A Rao, JZ Zhang
– Nature
(2023)
615,
836
(doi: 10.1038/s41586-023-05763-9)
The 2022 solar fuels roadmap
G Segev, J Kibsgaard, C Hahn, ZJ Xu, WH Cheng, TG Deutsch, C Xiang, JZ Zhang, L Hammarström, DG Nocera, AZ Weber, P Agbo, T Hisatomi, FE Osterloh, K Domen, FF Abdi, S Haussener, DJ Miller, S Ardo, PC McIntyre, T Hannappel, S Hu, H Atwater, JM Gregoire, MZ Ertem, ID Sharp, KS Choi, JS Lee, O Ishitani, JW Ager, RR Prabhakar, AT Bell, SW Boettcher, K Vincent, K Takanabe, V Artero, R Napier, BR Cuenya, MTM Koper, R Van De Krol, F Houle
– Journal of Physics D
(2022)
55,
323003
(doi: 10.1088/1361-6463/ac6f97)
Synthetic biology and bioelectrochemical tools for electrogenetic system engineering.
JM Lawrence, Y Yin, P Bombelli, A Scarampi, M Storch, LT Wey, A Climent-Catala, PixCell iGEM Team, GS Baldwin, D O'Hare, CJ Howe, JZ Zhang, TE Ouldridge, R Ledesma-Amaro
– Science Advances
(2022)
8,
eabm5091
(doi: 10.1126/sciadv.abm5091)
3D-printed hierarchical pillar array electrodes for high-performance semi-artificial photosynthesis.
X Chen, JM Lawrence, LT Wey, L Schertel, Q Jing, S Vignolini, CJ Howe, S Kar-Narayan, JZ Zhang
– Nature Materials
(2022)
21,
811
(doi: 10.1038/s41563-022-01205-5)
A biophotoelectrochemical approach to unravelling the role of cyanobacterial cell structures in exoelectrogenesis
LT Wey, JM Lawrence, X Chen, R Clark, DJ Lea-Smith, JZ Zhang, CJ Howe
– Electrochimica Acta
(2021)
395,
139214
(doi: 10.1016/j.electacta.2021.139214)
Phenazines as model low-midpoint potential electron shuttles for photosynthetic bioelectrochemical systems
ER Clifford, RW Bradley, LT Wey, JM Lawrence, X Chen, CJ Howe, JZ Zhang
– Chem Sci
(2021)
12,
3328
(doi: 10.1039/d0sc05655c)
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Research Group

Research Interest Groups

Telephone number

01223 336426

Email address

jz366@cam.ac.uk

College

Newnham College

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