Yusuf Hamied Department of Chemistry

Professor David Spring

Professor of Chemistry & Chemical Biology / EPSRC Established Career Research Fellow

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

PNA to DNA to microarray decoding facilitates ligand discovery.
WRJD Galloway, DR Spring
Chemistry & biology
(2011)
18
(doi: 10.1016/j.chembiol.2011.10.002)
Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site.
VM Bolanos-Garcia, T Lischetti, D Matak-Vinković, E Cota, PJ Simpson, DY Chirgadze, DR Spring, CV Robinson, J Nilsson, TL Blundell
Structure (London, England : 1993)
(2011)
19
(doi: 10.1016/j.str.2011.09.017)
Aryl-aryl bond formation by the fluoride-free cross-coupling of aryldisiloxanes with aryl bromides
CM Boehner, EC Frye, KMG O'Connell, WRJD Galloway, HF Sore, PG Dominguez, D Norton, DG Hulcoop, M Owen, G Turner, C Crawford, H Horsley, DR Spring
Chemistry A European Journal
(2011)
17
(doi: 10.1002/chem.201102285)
2-Heptyl-4-quinolone, a precursor of the Pseudomonas quinolone signal molecule, modulates swarming motility in Pseudomonas aeruginosa.
D-G Ha, JH Merritt, TH Hampton, JT Hodgkinson, M Janecek, DR Spring, M Welch, GA O'Toole
Journal of Bacteriology
(2011)
193
(doi: 10.1128/JB.05929-11)
Stereoselective synthesis of disubstituted butadienes via copper-mediated coupling of alkenyl silanes
DT Blackwell, WRJD Galloway, DR Spring
Synlett
(2011)
(doi: 10.1055/s-0030-1261150)
Stereoselective Synthesis of Disubstituted Butadienes via Copper-Mediated Coupling of Alkenyl Silanes
D Spring, D Blackwell, W Galloway
Synlett
(2011)
2011
(doi: 10.1055/s-0030-1261150)
A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium
JP Ramsay, NR Williamson, DR Spring, GPC Salmond
Proc Natl Acad Sci U S A
(2011)
108
(doi: 10.1073/pnas.1109169108)
Chemogenomics approaches for receptor deorphanization and extensions of the chemogenomics concept to phenotypic space
E van der Horst, JE Peironcely, GJP van Westen, OO van den Hoven, WRJD Galloway, DR Spring, JK Wegner, HWT van Vlijmen, AP Ijzerman, JP Overington, A Bender
Curr Top Med Chem
(2011)
11
(doi: 10.2174/156802611796391230)
Efficient synthesis of Fmoc-protected azido amino acids
YH Lau, DR Spring
Synlett
(2011)
(doi: 10.1055/s-0030-1260950)
Efficient Synthesis of Fmoc-Protected Azido Amino Acids
D Spring, Y Lau
Synlett
(2011)
2011
(doi: 10.1055/s-0030-1260950)

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address

spring@ch.cam.ac.uk

College

Trinity College
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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