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Yusuf Hamied Department of Chemistry

 

Professor David Spring

Professor of Chemistry & Chemical Biology / EPSRC Established Career Research Fellow

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

A quorum-sensing molecule acts as a morphogen controlling gas vesicle organelle biogenesis and adaptive flotation in an enterobacterium.
JP Ramsay, NR Williamson, DR Spring, GPC Salmond
– Proc Natl Acad Sci U S A
(2011)
108,
14932
(doi: 10.1073/pnas.1109169108)
Chemogenomics approaches for receptor deorphanization and extensions of the chemogenomics concept to phenotypic space.
E van der Horst, JE Peironcely, GJP van Westen, OO van den Hoven, WRJD Galloway, DR Spring, JK Wegner, HWT van Vlijmen, AP Ijzerman, JP Overington, A Bender
– Current topics in medicinal chemistry
(2011)
11,
1964
(doi: 10.2174/156802611796391230)
Efficient synthesis of Fmoc-protected azido amino acids
YH Lau, DR Spring
– Synlett
(2011)
1917
(doi: 10.1055/s-0030-1260950)
Efficient Synthesis of Fmoc-Protected Azido Amino Acids
YH Lau, DR Spring
– Synlett
(2011)
2011,
1917
(doi: 10.1055/s-0030-1260950)
Small molecules in biology
A Tavassoli, AD Hamilton, DR Spring
– Chemical Society reviews
(2011)
40,
4269
(doi: 10.1039/c1cs90028e)
Robust routes for the synthesis of N-acylated-L-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity
JT Hodgkinson, WRJD Galloway, M Casoli, H Keane, XB Su, GPC Salmond, M Welch, DR Spring
– Tetrahedron Letters
(2011)
52,
3291
(doi: 10.1016/j.tetlet.2011.04.059)
Robust routes for the synthesis of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity
JT Hodgkinson, WRJD Galloway, M Casoli, H Keane, X Su, GPC Salmond, M Welch, DR Spring
– Tetrahedron Letters
(2011)
52,
3291
(doi: 10.1016/j.tetlet.2011.04.059)
Regioselectivity in thermal rhodium(II)-catalysed Büchner-type reactions of substituted aryl halides: Studies towards the synthesis of halide-substituted cycloheptatrienes
EE Wyatt, WRJD Galloway, DR Spring
– Synlett
(2011)
1449
(doi: 10.1055/s-0030-1260562)
Regioselectivity in Thermal Rhodium(II)-Catalysed Buchner-Type Reactions of Substituted Aryl Halides: Studies towards the Synthesis of Halide-Substituted Cycloheptatrienes
EE Wyatt, WRJD Galloway, DR Spring
– Synlett
(2011)
2011,
1449
(doi: 10.1055/s-0030-1260562)
Chemical genetics
CJ O'Connor, L Laraia, DR Spring
– Chem Soc Rev
(2011)
40,
4332
(doi: 10.1039/c1cs15053g)
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Research Group

Research Interest Groups

Telephone number

01223 336498

Email address

spring@ch.cam.ac.uk

College

Trinity College

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    About the University

    Research at Cambridge