Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Efficient synthesis of Fmoc-protected azido amino acids
YH Lau, DR Spring
Synlett
(2011)
Small molecules in biology
A Tavassoli, AD Hamilton, DR Spring
Chemical Society reviews
(2011)
40
Robust routes for the synthesis of N-acylated-l-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity
JT Hodgkinson, WRJD Galloway, M Casoli, H Keane, X Su, GPC Salmond, M Welch, DR Spring
Tetrahedron Letters
(2011)
52
Regioselectivity in thermal rhodium(II)-catalysed Büchner-type reactions of substituted aryl halides: Studies towards the synthesis of halide-substituted cycloheptatrienes
EE Wyatt, WRJD Galloway, DR Spring
Synlett
(2011)
Chemical genetics
CJ O'Connor, L Laraia, DR Spring
Chem Soc Rev
(2011)
40
The Serratia LuxR family regulator CarR 39006 activates transcription independently of cognate quorum sensing signals
S Poulter, TM Carlton, DR Spring, GPC Salmond
Molecular Microbiology
(2011)
80
Fluorescent Sensing and Discrimination of ATP and ADP Based on a Unique Sandwich Assembly of Pyrene‐Adenine‐Pyrene
Z Xu, DR Spring, J Yoon
Chemistry - An Asian Journal
(2011)
6
Diversity-oriented synthesis of macrocyclic peptidomimetics
A Isidro-Llobet, T Murillo, P Bello, A Cilibrizzi, JT Hodgkinson, WRJD Galloway, A Bender, M Welch, DR Spring
Proceedings of the National Academy of Sciences
(2011)
108
Rational methods for the selection of diverse screening compounds.
DJ Huggins, AR Venkitaraman, DR Spring
ACS chemical biology
(2011)
6
Controlling the contents of microdroplets by exploiting the permeability of PDMS
J-U Shim, SN Patil, JT Hodgkinson, SD Bowden, DR Spring, M Welch, WTS Huck, F Hollfelder, C Abell
Lab on a Chip
(2011)
11

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address