Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Zn2+-triggered amide tautomerization produces a highly Zn2+-selective fluorescent sensor
Z Xu, J Yoon, D Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
241
Diversity-oriented synthesis of macrocyclic peptidomimetics
A Isidro-Llobet, T Murillo, P Bello, A Cilibrizzi, JT Hodgkinson, WRJD Galloway, A Bender, M Welch, DR Spring
Proceedings of the National Academy of Sciences
(2011)
108
Rational methods for the selection of diverse screening compounds
DJ Huggins, AR Venkitaraman, DR Spring
ACS chemical biology
(2011)
6
Controlling the contents of microdroplets by exploiting the permeability of PDMS
J-U Shim, SN Patil, JT Hodgkinson, SD Bowden, DR Spring, M Welch, WTS Huck, F Hollfelder, C Abell
Lab Chip
(2011)
11
Better leads come from diversity
WRJD Galloway, DR Spring
NATURE
(2011)
470
A question of library design
PJ Hajduk, WRJD Galloway, DR Spring
Nature
(2011)
470
Novel and efficient copper-catalysed synthesis of nitrogen-linked medium-ring biaryls.
JL Kenwright, WRJD Galloway, DT Blackwell, A Isidro-Llobet, J Hodgkinson, L Wortmann, SD Bowden, M Welch, DR Spring
Chemistry – A European Journal
(2011)
17
Importance of relative humidity in the oxidative ageing of organic aerosols: Case study of the ozonolysis of maleic acid aerosol
PJ Gallimore, P Achakulwisut, FD Pope, J Davies, DR Spring, M Kalberer
Atmospheric Chemistry and Physics Discussions
(2011)
11
Quorum sensing in Gram-negative bacteria: Small-molecule modulation of AHL and AI-2 quorum sensing pathways
WRJD Galloway, JT Hodgkinson, SD Bowden, M Welch, DR Spring
Chemical Reviews
(2010)
111
Induction-driven stabilization of the anion-π interaction in electron-rich aromatics as the key to fluoride inclusion in imidazolium-cage receptors.
Z Xu, NJ Singh, SK Kim, DR Spring, KS Kim, J Yoon
Chemistry
(2010)
17

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address