Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Induction of quorum sensing in microdroplets by transporting small molecule through PDMS
JU Shim, SN Patil, JT Hodgkinson, SD Bowden, DR Spring, M Welch, WTS Huck, F Hollfelder, C Abell
14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010 Microtas 2010
(2010)
1
Synthesis of highly substituted symmetrical 1,3-dienes via tandem carbocupration and organocuprate oxidation
SJ Aves, KG Pike, DR Spring
Synlett
(2010)
High throughput 'catch-and-release' synthesis within spatially discrete gel arrays
CM Boehner, DM Marsden, HF Sore, D Norton, DR Spring
Tetrahedron Letters
(2010)
51
Microwave and flow syntheses of Pseudomonas quinolone signal (PQS) and analogues.
JT Hodgkinson, WRJD Galloway, S Saraf, IR Baxendale, SV Ley, M Ladlow, M Welch, DR Spring
Org Biomol Chem
(2010)
9
Vinyldisiloxanes: Their synthesis, cross coupling and applications
HF Sore, CM Boehner, L Laraia, P Logoteta, C Prestinari, M Scott, K Williams, WRJD Galloway, DR Spring
Organic & Biomolecular Chemistry
(2010)
9
Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening.
DM Marsden, RL Nicholson, ME Skindersoe, WRJD Galloway, HF Sore, M Givskov, GPC Salmond, M Ladlow, M Welch, DR Spring
Org Biomol Chem
(2010)
8
Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules
WRJD Galloway, A Isidro-Llobet, DR Spring
Nature communications
(2010)
1
Discovery of a highly selective turn-on fluorescent probe for Ag+
Z Xu, S Zheng, J Yoon, DR Spring
The Analyst
(2010)
135
Diversity-oriented synthesis utilizing a two-directional macrocyclisation approach
KMG O'Connell, HT Horsley, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2010)
240
Diversity-oriented synthesis of macrocyclic peptidomimetic scaffolds
A Isidro-Llobet, P Bello, T Murillo, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2010)
240

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address