Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Diversity-oriented synthesis of disubstituted alkenes using masked silanols
HF Sore, DT Blackwell, SJF Macdonald, DR Spring
Org Lett
(2010)
12
Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule
J Hodgkinson, SD Bowden, WRJD Galloway, DR Spring, M Welch
Journal of Bacteriology
(2010)
192
Fluorescent chemosensors for Zn2+
Z Xu, J Yoon, DR Spring
Chemical Society reviews
(2010)
39
A selective and ratiometric Cu2+ fluorescent probe based on naphthalimide excimer–monomer switching
Z Xu, J Yoon, DR Spring
Chem Commun (Camb)
(2010)
46
Engineering of new prodigiosin-based biosensors of Serratia for facile detection of short-chain N-acyl homoserine lactone quorum-sensing molecules.
S Poulter, TM Carlton, X Su, DR Spring, GPC Salmond
Environmental microbiology reports
(2010)
2
Ratiometric fluorescent and colorimetric sensors for Cu2+ based on 4,5-disubstituted-1,8-naphthalimide and sensing cyanide via Cu2+ displacement approach
Z Xu, J Pan, DR Spring, J Cui, J Yoon
Tetrahedron
(2010)
66
Zn2+-triggered amide tautomerization produces a highly Zn 2+-selective, cell-permeable, and ratiometric fluorescent sensor
Z Xu, KH Baek, HN Kim, J Cui, X Qian, DR Spring, I Shin, J Yoon
Journal of the American Chemical Society
(2010)
132
Development of off-on fluorescent probes for heavy and transition metal ions
Z Xu, SJ Han, C Lee, J Yoon, DR Spring
Chem Commun (Camb)
(2010)
46
An Introduction to Diversity‐Oriented Synthesis
RJ Spandl, GL Thomas, M Diaz‐Gavilan, KMG O'Connell, DR Spring
(2009)
Diversity-oriented synthesis of bicyclic and tricyclic alkaloids
M Díaz-Gavilán, WRJD Galloway, KMG O'Connell, JT Hodkingson, DR Spring
Chem. Commun.
(2009)
46

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address