Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

Discovery of a quorum sensing modulator pharmacophore by 3D small-molecule microarray screening
DM Marsden, RL Nicholson, ME Skindersoe, WRJD Galloway, HF Sore, M Givskov, GPC Salmond, M Ladlow, M Welch, DR Spring
Organic and Biomolecular Chemistry
(2010)
8
Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules
WRJD Galloway, A Isidro-Llobet, DR Spring
Nature Communications
(2010)
1
Discovery of a highly selective turn-on fluorescent probe for Ag+.
Z Xu, S Zheng, J Yoon, DR Spring
The Analyst
(2010)
135
Diastereoselective 2-aza-Cope rearrangements and their applications in diversity-oriented synthesis
BM Ibbeson, DT Blackwell, DR Spring
ABSTR PAP AM CHEM S
(2010)
240
Adventures in diversity-oriented synthesis
WRJD Galloway, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2010)
240
Diversity-oriented synthesis utilizing a two-directional macrocyclisation approach
KMG O'Connell, HT Horsley, DR Spring
ABSTR PAP AM CHEM S
(2010)
240
Diversity-oriented synthesis of macrocyclic peptidomimetic scaffolds
A Isidro-Llobet, P Bello, T Murillo, DR Spring
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2010)
240
Diversity-oriented synthesis of disubstituted alkenes using masked silanols.
HF Sore, DT Blackwell, SJF Macdonald, DR Spring
Organic Letters
(2010)
12
Structure-Activity Analysis of thePseudomonasQuinolone Signal Molecule
J Hodgkinson, SD Bowden, WRJD Galloway, DR Spring, M Welch
Journal of bacteriology
(2010)
192
Fluorescent chemosensors for Zn(2+).
Z Xu, J Yoon, DR Spring
Chemical Society reviews
(2010)
39

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address