Professor of Chemistry & Chemical Biology

 

Our research interests originate from a desire to understand and exploit biological systems using organic synthesis primarily. Listed below are areas of research that we are exploring; for more detailed information visit the Spring Group web pages.

We collaborate with many chemical companies and academic groups around the world. The scientific education of group members in organic synthesis is given a high priority; however, they are encouraged also to learn and perform new techniques relating to their projects with our industrial and academic collaborators. Every effort is made so that group members achieve their career ambitions, usually jobs in academia or the chemical industries.

Spring Group Figure

 

 

Watch Professor David Spring discuss his research

Take a quick tour of the Spring Lab

For more detailed information please visit the Spring Group research pages.

Teaching

If you are looking for the teaching material from my lecture courses, then please go to the Moodle website.

Publications

For a list of all our publications please visit the Spring Group publication page.

Publications

The molecular basis of the host response to lipopolysaccharide.
CE Bryant, DR Spring, M Gangloff, NJ Gay
Nature reviews. Microbiology
(2009)
8
Synthesis of Biaryl-Containing Medium-Ring Systems by Organocuprate Oxidation: Applications in the Total Synthesis of Ellagitannin Natural Products
X Su, G Thomas, W Galloway, D Surry, R Spandl, D Spring
Synthesis
(2009)
2009
Mastering the chemical language of bacteria.
WRJD Galloway, JT Hodgkinson, M Welch, DR Spring
Chem Biol
(2009)
16
3D small-molecule microarrays
DM Marsden, RL Nicholson, M Ladlow, DR Spring
Chemical communications (Cambridge, England)
(2009)
Is synthesis the main hurdle for the generation of diversity in compound libraries for screening?
WR Galloway, DR Spring
Expert Opin Drug Discov
(2009)
4
The discovery of antibacterial agents using diversity-oriented synthesis
WRJD Galloway, A Bender, M Welch, DR Spring
Chem Commun (Camb)
(2009)
Synthesis of unprecedented scaffold diversity.
WRJD Galloway, M Diáz-Gavilán, A Isidro-Llobet, DR Spring
Angewandte Chemie International Edition
(2009)
48
Fluoride-free cross coupling using vinyldisiloxanes
HF Sore, CM Boehner, SJF MacDonald, D Norton, DJ Fox, DR Spring
Organic and Biomolecular Chemistry
(2009)
7
Towards quorum-quenching catalytic antibodies.
PB Kapadnis, E Hall, M Ramstedt, WRJD Galloway, M Welch, DR Spring
Chemical Communications
(2008)
Using chemical probes to investigate the sub-inhibitory effects of azithromycin
FG Glansdorp, RJ Spandl, JE Swatton, O Loiseleur, M Welch, DR Spring
Organic and Biomolecular Chemistry
(2008)
6

Research Group

Research Interest Groups

Telephone number

01223 336498

Email address