Pseudomonas aeruginosa PfpI is a methylglyoxalase.
L Grimm, A Wijaya, I Askenasy, RR Nazeer, H Seki, PD Brear, W Figueroa, DR Spring, M Welch
– Journal of Biological Chemistry
(2025)
301,
The 2-methylcitrate cycle and the glyoxylate shunt in Pseudomonas aeruginosa are linked through enzymatic redundancy
AJ Wijaya, SK Dolan, M Kohlstedt, L Gläser, P Brear, S Geddis, C Wittmann, DR Spring, M Welch
– J Biol Chem
(2025)
301,
Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome
R Eapen, C Okoye, C Stubbs, M Schimpl, T Tischer, E McCall, M Zacharopoulou, F Ferrer, D Barford, D Spring, C Lindon, C Phillips, LS Itzhaki
(2025)
Advances in the Release of Amide‐Containing Molecules
T Wharton, DR Spring
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2025)
31,
Correction to: Novel immunotherapeutics against LGR5 to target multiple cancer types (EMBO Molecular Medicine, (2024), 16, 9, (2233-2261), 10.1038/s44321-024-00121-2)
H-C Chen, N Mueller, K Stott, C Kapeni, E Rivers, CM Sauer, F Beke, SJ Walsh, N Ashman, L O'Brien, A Rafati Fard, A Ghodsinia, C Li, F Joud, O Giger, I Zlobec, I Olan, SJ Aitken, M Hoare, R Mair, E Serrao, JD Brenton, A Garcia-Gimenez, SE Richardson, B Huntly, DR Spring, M-O Skjoedt, K Skjødt, M de la Roche, M de la Roche
– EMBO Molecular Medicine
(2024)
16,
Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents
SR Stockwell, DE Scott, G Fischer, E Guarino, TPC Rooney, T-S Feng, T Moschetti, R Srinivasan, E Alza, A Asteian, C Dagostin, A Alcaide, M Rocaboy, B Blaszczyk, A Higueruelo, X Wang, M Rossmann, TR Perrior, TL Blundell, DR Spring, G McKenzie, C Abell, J Skidmore, AR Venkitaraman, M Hyvönen
– J Med Chem
(2024)
67,
Novel immunotherapeutics against LGR5 to target multiple cancer types
H-C Chen, N Mueller, K Stott, C Kapeni, E Rivers, CM Sauer, F Beke, SJ Walsh, N Ashman, L O'Brien, A Rafati Fard, A Ghodsinia, C Li, F Joud, O Giger, I Zlobec, I Olan, SJ Aitken, M Hoare, R Mair, E Serrao, JD Brenton, A Garcia-Gimenez, SE Richardson, B Huntly, DR Spring, M-O Skjoedt, K Skjødt, M de la Roche, M de la Roche
– EMBO Molecular Medicine
(2024)
16,
Tuneable thiol exchange linkers for traceless drug release applications in prodrugs and ADCs
R Walther, M Park, N Ashman, M Welch, JS Carroll, DR Spring
– Chem Commun (Camb)
(2024)
60,
Towards the Targeted Protein Degradation of PRMT1
PL Martin, FJ Pérez-Areales, SV Rao, SJ Walsh, JS Carroll, DR Spring
– Chemmedchem
(2024)
19,
Photoredox C(2)-Arylation of Indole- and Tryptophan-Containing Biomolecules.
BM da S Santos, FG Finelli, DR Spring
– Organic Letters
(2024)
26,
