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Yusuf Hamied Department of Chemistry

 

Publications by Professor Steve Ley CBE FRS FMedSci

The clerodane ring system: Investigating the viability of a direct Diels-Alder approach
AT Merritt, RH Pouwer, DJ Williams, CM Williams, SV Ley
– Organic & Biomolecular Chemistry
(2011)
9,
4745
(DOI: 10.1039/c1ob05422h)
Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.
M Baumann, IR Baxendale, C Kuratli, SV Ley, RE Martin, J Schneider
– ACS Combinatorial Science
(2011)
13,
405
(DOI: 10.1021/co2000357)
Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme
G Lupo, G Gestri, M O'Brien, RM Denton, RAS Chandraratna, SV Ley, WA Harris, SW Wilson
– Proceedings of the National Academy of Sciences
(2011)
108,
8698
(DOI: 10.1073/pnas.1103802108)
A breakthrough method for the accurate addition of reagents in multi-step segmented flow processing
H Lange, CF Carter, MD Hopkin, A Burke, JG Goode, IR Baxendale, SV Ley
– Chemical Science
(2011)
2,
765
(DOI: 10.1039/c0sc00603c)
An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals
M Baumann, IR Baxendale, SV Ley, N Nikbin
– Beilstein J Org Chem
(2011)
7,
442
(DOI: 10.3762/bjoc.7.57)
Azadirachtin: structural requirements for reducing growth and increasing mortality in lepidopterous larvae
MSJ SIMMONDS, WM BLANEY, SV LEY, JC ANDERSON, PL TOOGOOD
– Entomologia Experimentalis Et Applicata
(2011)
55,
169
(DOI: 10.1111/j.1570-7458.1990.tb01360.x)
Antifeedant effects of azadirachtin and structurally related compounds on lepidopterous larvae
WM BLANEY, MSJ SIMMONDS, SV LEY, JC ANDERSON, PL TOOGOOD
– Entomologia Experimentalis Et Applicata
(2011)
55,
149
(DOI: 10.1111/j.1570-7458.1990.tb01358.x)
Insect antifeedants: a behavioural and electrophysiological investigation of natural and synthetically derived clerodane diterpenoids
WM BLANEY, MSJ SIMMONDS, SV LEY, PS JONES
– Entomologia Experimentalis Et Applicata
(2011)
46,
267
(DOI: 10.1111/j.1570-7458.1988.tb01121.x)
Behavioural and neurophysiological responses of Spodoptera littoralis to azadirachtin and a range of synthetic analogues
MSJ SIMMONDS, WM BLANEY, SV LEY, JC ANDERSON, R BANTELI, AA DENHOLM, PCW GREEN, RB GROSSMAN, C GUTTERIDGE, L JENNENS, SC SMITH, PL TOOGOOD, A WOOD
– Entomologia Experimentalis et Applicata
(2011)
77,
69
(DOI: 10.1111/j.1570-7458.1995.tb01987.x)
Lesser-known enabling technologies for organic synthesis
M O'Brien, R Denton, SV Ley
– Synthesis
(2011)
1157
(DOI: 10.1055/s-0030-1259979)
Lesser-Known Enabling Technologies for Organic Synthesis
M O'Brien, R Denton, SV Ley
– Synthesis
(2011)
2011,
1157
(DOI: 10.1055/s-0030-1259979)
In-line monitoring for the accurate control of segmented flow processes
CF Carter, SV Ley
– ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2011)
241,
Oxidation reactions in segmented and continuous flow chemical processing using an N -(tert -Butyl)phenylsulfinimidoyl chloride monolith
H Lange, MJ Capener, AX Jones, CJ Smith, N Nikbin, IR Baxendale, SV Ley
– Synlett
(2011)
869
(DOI: 10.1055/s-0030-1259923)
Oxidation Reactions in Segmented and Continuous Flow Chemical Processing Using an <i>N</i>-(<i>tert</i>-Butyl)phenylsulfinimidoyl Chloride Monolith
H Lange, MJ Capener, AX Jones, CJ Smith, N Nikbin, IR Baxendale, SV Ley
– Synlett
(2011)
2011,
869
(DOI: 10.1055/s-0030-1259923)
Total synthesis of chloptosin: A dimeric cyclohexapeptide
AJ Oelke, F Antonietti, L Bertone, PB Cranwell, DJ France, RJM Goss, T Hofmann, S Knauer, SJ Moss, PC Skelton, RM Turner, G Wuitschik, SV Ley
– Chemistry (Weinheim an der Bergstrasse, Germany)
(2011)
17,
4183
(DOI: 10.1002/chem.201003216)
Continuous Flow Processing of Slurries: Evaluation of an Agitated Cell Reactor
DL Browne, BJ Deadman, R Ashe, IR Baxendale, SV Ley
– Organic Process Research and Development
(2011)
15,
693
(DOI: 10.1021/op2000223)
Synthesis of highly substituted nitropyrrolidines, nitropyrrolizines and nitropyrroles via multicomponent-multistep sequences within a flow reactor
M Baumann, IR Baxendale, A Kirschning, SV Ley, J Wegner
– Heterocycles
(2011)
82,
1297
(DOI: 10.3987/com-10-s(e)77)
Diastereoselective chain-elongation reactions using microreactors for applications in complex molecule assembly
CF Carter, H Lange, D Sakai, IR Baxendale, SV Ley
– Chemistry - A European Journal
(2011)
17,
3398
(DOI: 10.1002/chem.201003148)
Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins.
X Qi, F Loiseau, WL Chan, Y Yan, Z Wei, L-G Milroy, RM Myers, SV Ley, RJ Read, RW Carrell, A Zhou
– The Journal of biological chemistry
(2011)
286,
16163
(DOI: 10.1074/jbc.M110.171082)
The continuous-flow synthesis of carboxylic acids using CO2 in a tube-in-tube gas permeable membrane reactor.
A Polyzos, M O'Brien, TP Petersen, IR Baxendale, SV Ley
– Angewandte Chemie International Edition
(2011)
50,
1190
(DOI: 10.1002/anie.201006618)

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