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Yusuf Hamied Department of Chemistry

 

Publications by Professor Gonçalo Bernardes

Discovery of 2,4-dimethoxypyridines as novel autophagy inhibitors
L Robke, T Rodrigues, P Schröder, DJ Foley, GJL Bernardes, L Laraia, H Waldmann
– Tetrahedron
(2018)
74,
4531
(DOI: 10.1016/j.tet.2018.07.021)
Synthesis and Biological Evaluation of Homogenous Thiol-Linked NHC*–Au–Albumin and –Trastuzumab Bioconjugates
MJ Matos, C Labão-Almeida, C Sayers, O Dada, M Tacke, GJL Bernardes
– Chemistry - A European Journal
(2018)
24,
12250
(DOI: 10.1002/chem.201800872)
Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor.
T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, P Akkapeddi, SA Lobo, A Koeberle, F Corzana, EN da Silva Júnior, O Werz, GJL Bernardes
– Chem Sci
(2018)
9,
6899
(DOI: 10.1039/c8sc02634c)
Site-selective installation of an electrophilic handle on proteins for bioconjugation
B Lee, S Sun, E Jiménez-Moreno, AA Neves, GJL Bernardes
– Bioorganic & medicinal chemistry
(2018)
26,
3060
(DOI: 10.1016/j.bmc.2018.02.028)
Sustainable Polysulfides for Oil Spill Remediation: Repurposing Industrial Waste for Environmental Benefit
MJH Worthington, CJ Shearer, LJ Esdaile, JA Campbell, CT Gibson, SK Legg, Y Yin, NA Lundquist, JR Gascooke, IS Albuquerque, JG Shapter, GG Andersson, DA Lewis, GJL Bernardes, JM Chalker
– Advanced Sustainable Systems
(2018)
2,
1800024
(DOI: 10.1002/adsu.201800024)
Artificial Intelligence Recognizes β-Lapachone as an Allosteric 5- Lipoxygenase Inhibitor
G Bernardes, T Rodrigues, M Werner, J Roth, E da Cruz, M Marques, S Lobo, A Koeberle, F Corzana, E N. da Silva Júnior, O Werz
(2018)
(DOI: 10.26434/chemrxiv.6026795.v1)
Chemo- and Regioselective Lysine Modification on Native Proteins
MJ Matos, BL Oliveira, N Martínez-Sáez, A Guerreiro, PMSD Cal, J Bertoldo, M Maneiro, E Perkins, J Howard, MJ Deery, JM Chalker, F Corzana, G Jiménez-Osés, GJL Bernardes
– Journal of the American Chemical Society
(2018)
140,
4004
(DOI: 10.1021/jacs.7b12874)
Antikörpergerichtete Therapien: Quo vadis?
T Rodrigues, GJL Bernardes
– Angewandte Chemie
(2018)
130,
2050
(DOI: 10.1002/ange.201712185)
A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging.
BJ Stenton, BL Oliveira, MJ Matos, L Sinatra, GJL Bernardes
– Chem Sci
(2018)
9,
4185
(DOI: 10.1039/c8sc00256h)
Development of antibody-directed therapies: quo vadis?
T Rodrigues, GJL Bernardes
– Angewandte Chemie - International Edition
(2018)
57,
2032
(DOI: 10.1002/anie.201712185)
A silicon-labelled amino acid suitable for late-stage fluorination and unexpected oxidative cleavage reactions in the preparation of a key intermediate in the Strecker synthesis
KR Scroggie, LJ Alcock, MJ Matos, GJL Bernardes, MV Perkins, JM Chalker
– Peptide Science
(2018)
110,
e24069
(DOI: 10.1002/pep2.24069)
A Fluorogenic Probe for Cell Surface Phosphatidylserine Using an Intramolecular Indicator Displacement Sensing Mechanism
VE Zwicker, BL Oliveira, JH Yeo, ST Fraser, GJL Bernardes, EJ New, KA Jolliffe
– Angewandte Chemie - International Edition
(2018)
58,
3087
(DOI: 10.1002/anie.201812489)
The Use of Fluoroproline in MUC1 Antigen Enables Efficient Detection of Antibodies in Patients with Prostate Cancer
VJ Somovilla, IA Bermejo, IS Albuquerque, N Martínez-Sáez, J Castro-López, F García-Martín, I Compañón, H Hinou, S Nishimura, J Jiménez-Barbero, JL Asensio, A Avenoza, JH Busto,, R Hurtado-Guerrero, JM Peregrina, GJ Lopes Bernardes, F Corzana1
– J Am Chem Soc
(2017)
139,
18255
(DOI: 10.1021/jacs.7b09447)
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation.
AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, VJ Somovilla, T Rodrigues, K Nicholls, B Xie, G Jiménez-Osés, KM Brindle, AA Neves, GJL Bernardes
– J Am Chem Soc
(2017)
139,
18365
(DOI: 10.1021/jacs.7b10702)
Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites
J Dadová, K-J Wu, PG Isenegger, JC Errey, GJL Bernardes, JM Chalker, L Raich, C Rovira, BG Davis
– ACS Central Science
(2017)
3,
1168
(DOI: 10.1021/acscentsci.7b00341)
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez-Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJ Lopes Bernardes
– Angewandte Chemie (International ed. in English)
(2017)
56,
14963
(DOI: 10.1002/anie.201708847)
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
N Martínez‐Sáez, S Sun, D Oldrini, P Sormanni, O Boutureira, F Carboni, I Compañón, MJ Deery, M Vendruscolo, F Corzana, R Adamo, GJL Bernardes
– Angewandte Chemie
(2017)
129,
15159
(DOI: 10.1002/ange.201708847)
Enhanced Permeability and Binding Activity of Isobutylene-Grafted Peptides.
S Sun, I Compañón, N Martínez-Sáez, JD Seixas, O Boutureira, F Corzana, GJL Bernardes
– Chembiochem
(2017)
19,
48
(DOI: 10.1002/cbic.201700586)
Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils
GJ Lopes Bernardes
– Chemistry - A European Journal
(2017)
23,
16219
(DOI: 10.1002/chem.201702871)
A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases
JB Bertoldo, T Rodrigues, L Dunsmore, FA Aprile, MC Marques, LA Rosado, O Boutureira, TB Steinbrecher, W Sherman, F Corzana, H Terenzi, GJL Bernardes
– Chem
(2017)
3,
665
(DOI: 10.1016/j.chempr.2017.07.009)

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