Triazole-Based Thiamine Analogues as Inhibitors of Thiamine Pyrophosphate-Dependent Enzymes: 1,3-Dicarboxylate for Metal Binding.
– ACS Omega
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Structural and Functional Basis of GenB2 Isomerase Activity from Gentamicin Biosynthesis.
– ACS Chemical Biology
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19,
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Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-<scp>d</scp>-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes
– RSC medicinal chemistry
(2024)
15,
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Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase
– Bioorg Med Chem Lett
(2023)
98,
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Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes.
– Organic and Biomolecular Chemistry
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Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes: Systematic investigation through Scaffold-Hopping and C2-Functionalisation
– Bioorganic Chemistry
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Biosynthesis of Antifungal Solanimycin May Involve an Iterative Nonribosomal Peptide Synthetase Module
– ACS Chem Biol
(2023)
18,
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Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues
– ACS Medicinal Chemistry Letters
(2023)
14,
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Preclinical PET Imaging of Tumor Cell Death following Therapy Using Gallium-68-Labeled C2Am
– Cancers (Basel)
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15,
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Furan-based Inhibitors of Pyruvate Dehydrogenase: SAR Study, Biochemical Evaluation and Computational Analysis
– Organic & biomolecular chemistry
(2023)
21,
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Correction: Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity.
– RSC Medicinal Chemistry
(2023)
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Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase.
– Organic and Biomolecular Chemistry
(2022)
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Solanimycin: Biosynthesis and Distribution of a New Antifungal Antibiotic Regulated by Two Quorum-Sensing Systems.
– mBio
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Enzyme-Catalyzed Spiroacetal Formation in Polyketide Antibiotic Biosynthesis
– Journal of the American Chemical Society
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Metabolic Glycan Labelling of Cancer Cells using Variably Acetylated Monosaccharides
– Bioconjug Chem
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33,
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Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity.
– RSC Medicinal Chemistry
(2022)
13,
817
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Prodrugs of pyrophosphates and bisphosphonates: disguising phosphorus oxyanions.
– RSC medicinal chemistry
(2022)
13,
375
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Mechanistic Insights into Dideoxygenation in Gentamicin Biosynthesis
– ACS Catalysis
(2021)
11,
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Revision in the first steps of the biosynthesis of the red antibiotic prodigiosin: use of a synthetic thioester to validate a new intermediate
– RSC Chem Biol
(2021)
2,
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