Yusuf Hamied Department of Chemistry

Publications by Professor Sir Alan Fersht FRS

Distinguishing between cooperative and unimodal downhill protein folding
F Huang, S Sato, TD Sharpe, L Ying, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2007)
104
(doi: 10.1073/pnas.0609717104)
Structural biology of the tumor suppressor p53 and cancer-associated mutants.
AC Joerger, AR Fersht
Adv Cancer Res
(2007)
97
(doi: 10.1016/s0065-230x(06)97001-8)
General structural motifs of amyloid protofilaments (vol 103, pg 16248, 2006)
N Ferguson, J Becker, H Tidow, S Tremmel, TD Sharpe, G Krause, J Flinders, M Petrovich, J Berriman, H Oschkinat, AR Fersht
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2006)
103
General structural motifs of amyloid protofilaments
N Ferguson, J Becker, H Tidow, S Tremmel, TD Sharpe, G Krause, J Flinders, M Petrovich, J Berriman, H Oschkinat, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2006)
103
(doi: 10.1073/pnas.0607815103)
Pro-sequence-assisted protein folding.
J Eder, AR Fersht
Molecular microbiology
(2006)
16
(doi: 10.1111/j.1365-2958.1995.tb02423.x)
Structural basis for understanding oncogenic p53 mutations and designing rescue drugs
AC Joerger, HC Ang, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2006)
103
(doi: 10.1073/pnas.0607286103)
FRET analysis of denaturation of engrailed homeodomain
F Huang, AR Fersht
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2006)
232
Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2)
H Tidow, DB Veprintsev, SMV Freund, AR Fersht
The Journal of biological chemistry
(2006)
281
(doi: 10.1074/jbc.M604725200)
Characterization of the native and fibrillar conformation of the human Nα‐acetyltransferase ARD1
N Sánchez-Puig, AR Fersht
Protein science : a publication of the Protein Society
(2006)
15
(doi: 10.1110/ps.062264006)
Phi-analysis of the folding of the B domain of protein A using multiple optical probes.
S Sato, TL Religa, AR Fersht
J Mol Biol
(2006)
360
(doi: 10.1016/j.jmb.2006.05.051)
phi-Analysis at the experimental limits: Mechanism of beta-hairpin formation
M Petrovich, AL Jonsson, N Ferguson, V Daggett, AR Fersht
Journal of molecular biology
(2006)
360
(doi: 10.1016/j.jmb.2006.05.050)
Effects of common cancer mutations on stability and DNA binding of full-length p53 compared with isolated core domains
HC Ang, AC Joerger, S Mayer, AR Fersht
Journal of Biological Chemistry
(2006)
281
(doi: 10.1074/jbc.M604209200)
Core domain interactions in full-length p53 in solution.
DB Veprintsev, SMV Freund, A Andreeva, SE Rutledge, H Tidow, JMP Cañadillas, CM Blair, AR Fersht
Proceedings of the National Academy of Sciences
(2006)
103
(doi: 10.1073/pnas.0511130103)
Solution structure of p53 core domain: structural basis for its instability.
JMP Cañadillas, H Tidow, SMV Freund, TJ Rutherford, HC Ang, AR Fersht
Proc Natl Acad Sci U S A
(2006)
103
(doi: 10.1073/pnas.0510941103)
The central region of HDM2 provides a second binding site for p53
GW Yu, S Rudiger, D Veprintsev, S Freund, MR Fernandez-Fernandez, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2006)
103
(doi: 10.1073/pnas.0510343103)
Solution structure of the C4 zinc finger domain of HDM2
GW Yu, MD Allen, A Andreeva, AR Fersht, M Bycroft
Protein Science
(2005)
15
(doi: 10.1110/ps.051927306)
The transition state for folding of a peripheral subunit-binding domain contains robust and ionic-strength dependent characteristics
N Ferguson, TD Sharpe, CM Johnson, AR Fersht
Journal of molecular biology
(2005)
356
(doi: 10.1016/j.jmb.2005.12.016)
Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents.
L Briseño-Roa, J Hill, S Notman, D Sellers, AP Smith, CM Timperley, J Wetherell, NH Williams, GR Williams, AR Fersht, AD Griffiths
J Med Chem
(2005)
49
(doi: 10.1021/jm050518j)
Ultra-fast Barrier-limited Folding in the Peripheral Subunit-binding Domain Family
N Ferguson, TD Sharpe, PJ Schartau, S Sato, MD Allen, CM Johnson, TJ Rutherford, AR Fersht
J Mol Biol
(2005)
353
(doi: 10.1016/j.jmb.2005.08.031)
Solution structure of a protein denatured state and folding intermediate.
TL Religa, JS Markson, U Mayor, SMV Freund, AR Fersht
Nature
(2005)
437
(doi: 10.1038/nature04054)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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