Yusuf Hamied Department of Chemistry

Publications by Professor Sir Alan Fersht FRS

Distinguishing between cooperative and unimodal downhill protein folding
F Huang, S Sato, TD Sharpe, L Ying, AR Fersht
Proc Natl Acad Sci U S A
(2007)
104
(doi: 10.1073/pnas.0609717104)
Structural Biology of the Tumor Suppressor p53 and Cancer‐Associated Mutants
AC Joerger, AR Fersht
ADVANCES IN CANCER RESEARCH, VOL 97
(2007)
97
(doi: 10.1016/S0065-230X(06)97001-8)
General structural motifs of amyloid protofilaments (vol 103, pg 16248, 2006)
N Ferguson, J Becker, H Tidow, S Tremmel, TD Sharpe, G Krause, J Flinders, M Petrovich, J Berriman, H Oschkinat, AR Fersht
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2006)
103
General structural motifs of amyloid protofilaments.
N Ferguson, J Becker, H Tidow, S Tremmel, TD Sharpe, G Krause, J Flinders, M Petrovich, J Berriman, H Oschkinat, AR Fersht
Proceedings of the National Academy of Sciences
(2006)
103
(doi: 10.1073/pnas.0607815103)
Pro‐sequence‐assisted protein folding
J Eder, AR Fersht
Mol Microbiol
(2006)
16
(doi: 10.1111/j.1365-2958.1995.tb02423.x)
Structural basis for understanding oncogenic p53 mutations and designing rescue drugs.
AC Joerger, HC Ang, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2006)
103
(doi: 10.1073/pnas.0607286103)
FRET analysis of denaturation of engrailed homeodomain
F Huang, AR Fersht
ABSTR PAP AM CHEM S
(2006)
232
Effects of oncogenic mutations and DNA response elements on the binding of p53 to p53-binding protein 2 (53BP2).
H Tidow, DB Veprintsev, SMV Freund, AR Fersht
The Journal of biological chemistry
(2006)
281
(doi: 10.1074/jbc.m604725200)
Characterization of the native and fibrillar conformation of the human N alpha-acetyltransferase ARD1
N Sánchez-Puig, AR Fersht
Protein science : a publication of the Protein Society
(2006)
15
(doi: 10.1110/ps.062264006)
Φ-Analysis of the Folding of the B Domain of Protein A Using Multiple Optical Probes
S Sato, TL Religa, AR Fersht
Journal of Molecular Biology
(2006)
360
(doi: 10.1016/j.jmb.2006.05.051)
phi-Analysis at the experimental limits: Mechanism of beta-hairpin formation
M Petrovich, AL Jonsson, N Ferguson, V Daggett, AR Fersht
Journal of molecular biology
(2006)
360
(doi: 10.1016/j.jmb.2006.05.050)
Effects of Common Cancer Mutations on Stability and DNA Binding of Full-length p53 Compared with Isolated Core Domains
HC Ang, AC Joerger, S Mayer, AR Fersht
Journal of Biological Chemistry
(2006)
281
(doi: 10.1074/jbc.M604209200)
Solution structure of p53 core domain: Structural basis for its instability
JMP Cañadillas, H Tidow, SMV Freund, TJ Rutherford, HC Ang, AR Fersht
Proc Natl Acad Sci U S A
(2006)
103
(doi: 10.1073/pnas.0510941103)
Core domain interactions in full-length p53 in solution.
DB Veprintsev, SMV Freund, A Andreeva, SE Rutledge, H Tidow, JMP Cañadillas, CM Blair, AR Fersht
Proc Natl Acad Sci U S A
(2006)
103
(doi: 10.1073/pnas.0511130103)
The central region of HDM2 provides a second binding site for p53
GW Yu, S Rudiger, D Veprintsev, S Freund, MR Fernandez-Fernandez, AR Fersht
Proc Natl Acad Sci U S A
(2006)
103
(doi: 10.1073/pnas.0510343103)
Solution structure of the C4 zinc finger domain of HDM2
GW Yu, MD Allen, A Andreeva, AR Fersht, M Bycroft
Protein science : a publication of the Protein Society
(2005)
15
(doi: 10.1110/ps.051927306)
The transition state for folding of a peripheral subunit-binding domain contains robust and ionic-strength dependent characteristics.
N Ferguson, TD Sharpe, CM Johnson, AR Fersht
Journal of molecular biology
(2005)
356
(doi: 10.1016/j.jmb.2005.12.016)
Analogues with Fluorescent Leaving Groups for Screening and Selection of Enzymes That Efficiently Hydrolyze Organophosphorus Nerve Agents
L Briseño-Roa, J Hill, S Notman, D Sellers, AP Smith, CM Timperley, J Wetherell, NH Williams, GR Williams, AR Fersht, AD Griffiths
Journal of medicinal chemistry
(2005)
49
(doi: 10.1021/jm050518j)
Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family.
N Ferguson, TD Sharpe, PJ Schartau, S Sato, MD Allen, CM Johnson, TJ Rutherford, AR Fersht
Journal of molecular biology
(2005)
353
(doi: 10.1016/j.jmb.2005.08.031)
Solution structure of a protein denatured state and folding intermediate.
TL Religa, JS Markson, U Mayor, SMV Freund, AR Fersht
Nature
(2005)
437
(doi: 10.1038/nature04054)
Yusuf Hamied Department of Chemistry
Lensfield Road
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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