Tumor suppressor p53 slides on DNA with low friction and high stability
A Tafvizi, F Huang, JS Leith, AR Fersht, LA Mirny, AM van Oijen
Biophys J
(2008)
95
Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain
M Wells, H Tidow, TJ Rutherford, P Markwick, MR Jensen, E Mylonas, DI Svergun, M Blackledge, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2008)
105
High Temperature Unfolding Simulations of the TRPZ1 Peptide
G Settanni, AR Fersht
Biophysical journal
(2008)
94
A Guide to Measuring and Interpreting Φ‐values
NR Guydosh, AR Fersht
(2008)
1
Algorithm for prediction of tumour suppressor p53 affinity for binding sites in DNA.
DB Veprintsev, AR Fersht
Nucleic acids research
(2008)
36
Fluorescence resonance energy transfer analysis of the folding pathway of Engrailed Homeodomain.
F Huang, G Settanni, AR Fersht
Protein Engineering Design and Selection
(2008)
21
Demonstration by burst-phase analysis of a robust folding intermediate in the FF domain.
P Jemth, CM Johnson, S Gianni, AR Fersht
Protein Eng Des Sel
(2008)
21
The role of the turn in β-hairpin formation during WW domain folding
T Sharpe, AL Jonsson, TJ Rutherford, V Daggett, AR Fersht
Protein science : a publication of the Protein Society
(2007)
16
Comparative biophysical characterization of p53 with the pro-apoptotic BAK and the anti-apoptotic BCL-x(L)
B Sot, SMV Freund, AR Fersht
J Biol Chem
(2007)
282
Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex.
H Tidow, R Melero, E Mylonas, SMV Freund, JG Grossmann, JM Carazo, DI Svergun, M Valle, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2007)
104
Correlation of levels of folded recombinant p53 in Escherichia coli with thermodynamic stability in vitro
S Mayer, S Rüdiger, HC Ang, AC Joerger, AR Fersht
J Mol Biol
(2007)
372
Searching for multiple folding pathways of a nearly symmetrical protein: temperature dependent phi-value analysis of the B domain of protein A.
S Sato, AR Fersht
Journal of molecular biology
(2007)
372
The folding pathway of an FF domain: characterization of an on-pathway intermediate state under folding conditions by (15)N, (13)C(alpha) and (13)C-methyl relaxation dispersion and (1)H/(2)H-exchange NMR spectroscopy.
DM Korzhnev, TL Religa, P Lundström, AR Fersht, LE Kay
J Mol Biol
(2007)
372
The helix-turn-helix motif as an ultrafast independently folding domain: the pathway of folding of Engrailed homeodomain.
TL Religa, CM Johnson, DM Vu, SH Brewer, RB Dyer, AR Fersht
Proc Natl Acad Sci U S A
(2007)
104
Solution Structure of ASPP2 N-terminal Domain (N-ASPP2) Reveals a Ubiquitin-like Fold
H Tidow, A Andreeva, TJ Rutherford, AR Fersht
Journal of Molecular Biology
(2007)
371
Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53.
DP Teufel, SM Freund, M Bycroft, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2007)
104
Structure-function-rescue: the diverse nature of common p53 cancer mutants.
AC Joerger, AR Fersht
Oncogene
(2007)
26
Conformational entropy of alanine versus glycine in protein denatured states.
KA Scott, DOV Alonso, S Sato, AR Fersht, V Daggett
Proceedings of the National Academy of Sciences
(2007)
104
Structural biology - Analysis of 'downhill' protein folding
N Ferguson, TD Sharpe, CM Johnson, PJ Schartau, AR Fersht
Nature
(2007)
445
Folding and binding: implementing the game plan - Editorial overview
AR Fersht, V Daggett
Current Opinion in Structural Biology
(2007)
17