Ultraslow oligomerization equilibria of p53 and its implications.
E Natan, D Hirschberg, N Morgner, CV Robinson, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2009)
106
Effects of Stability on the Biological Function of p53*
KH Khoo, S Mayer, AR Fersht
J Biol Chem
(2009)
284
Adaptive Evolution of p53 Thermodynamic Stability
KH Khoo, A Andreeva, AR Fersht
J Mol Biol
(2009)
393
The accessory subunit of mitochondrial DNA polymerase gamma determines the DNA content of mitochondrial nucleoids in human cultured cells.
M Di Re, H Sembongi, J He, A Reyes, T Yasukawa, P Martinsson, LJ Bailey, S Goffart, JD Boyd-Kirkup, TS Wong, AR Fersht, JN Spelbrink, IJ Holt
Nucleic acids research
(2009)
37
Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics.
S Rajagopalan, A Andreeva, DP Teufel, SM Freund, AR Fersht
J Biol Chem
(2009)
284
Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core.
KH Khoo, AC Joerger, SMV Freund, AR Fersht
Protein Eng Des Sel
(2009)
22
The Folding Mechanism of BBL: Plasticity of Transition-State Structure Observed within an Ultrafast Folding Protein Family
H Neuweiler, TD Sharpe, TJ Rutherford, CM Johnson, MD Allen, N Ferguson, AR Fersht
Journal of molecular biology
(2009)
390
PRIMA-1 reactivates mutant p53 by covalent binding to the core domain.
JMR Lambert, P Gorzov, DB Veprintsev, M Söderqvist, D Segerbäck, J Bergman, AR Fersht, P Hainaut, KG Wiman, VJN Bykov
Cancer Cell
(2009)
15
Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2
DP Teufel, M Bycroft, AR Fersht
Oncogene
(2009)
28
Downhill versus Barrier-Limited Folding of BBL 1: Energetic and Structural Perturbation Effects upon Protonation of a Histidine of Unusually Low pKa
E Arbely, TJ Rutherford, TD Sharpe, N Ferguson, AR Fersht
Journal of Molecular Biology
(2009)
387
Corrigendum to “Conservation of Transition State Structure in Fast Folding Peripheral Subunit-Binding Domains” [J. Mol. Biol. 383 (2008) 224–237]
TD Sharpe, N Ferguson, CM Johnson, AR Fersht
Journal of Molecular Biology
(2009)
387
Time-resolved fluorescence resonance energy transfer study shows a compact denatured state of the b domain of protein A
F Huang, E Lerner, S Sato, D Amir, E Haas, AR Fersht
Biochemistry
(2009)
48
Modulation of the Oligomerization State of p53 by Differential Binding of Proteins of the S100 Family to p53 Monomers and Tetramers
J van Dieck, MR Fernandez-Fernandez, DB Veprintsev, AR Fersht
Journal of Biological Chemistry
(2009)
284
Molecular basis of the interactions between the p73 N terminus and p300: effects on transactivation and modulation by phosphorylation.
S Burge, DP Teufel, FM Townsley, SMV Freund, M Bycroft, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2009)
106
Downhill versus Barrier-Limited Folding of BBL. 3. Heterogeneity of the Native State of the BBL Peripheral Subunit Binding Domain and Its Implications for Folding Mechanisms
G Settanni, AR Fersht
Journal of molecular biology
(2009)
387
Solution Structure of the U11-48K CHHC Zinc-Finger Domain that Specifically Binds the 5′ Splice Site of U12-Type Introns
H Tidow, A Andreeva, TJ Rutherford, AR Fersht
Structure (London, England : 1993)
(2009)
17
Protein folding and binding: moving into unchartered territory
V Daggett, AR Fersht
Current Opinion in Structural Biology
(2009)
19
Sequence-Dependent Kinetics of One-Dimensional Diffusion of p53 on DNA
JS Leith, A Tafvizi, F Huang, AR Fersht, LA Mirny, AM van Oijen
Biophysical Journal
(2009)
96
Single-molecule Studies Of p53 Sliding Along DNA
A Tafvizi, JS Leith, F Huang, AR Fersht, LA Mirny, AM van Oijen
Biophysical Journal
(2009)
96
The novel p53 isoform "delta p53" is a misfolded protein and does not bind the p21 promoter site
MM García-Alai, H Tidow, E Natan, FM Townsley, DB Veprintsev, AR Fersht
Protein Science
(2009)
17