Determination of the folding transition states of barnase by using ΦI-value-restrained simulations validated by double mutant ΦIJ-values
X Salvatella, CM Dobson, AR Fersht, M Vendruscolo
Proceedings of the National Academy of Sciences
(2005)
102
Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding.
GWN White, S Gianni, JG Grossmann, P Jemth, AR Fersht, V Daggett
Journal of molecular biology
(2005)
350
The crystal structure of human CD1d with and without alpha-galactosylceramide
M Koch, VS Stronge, D Shepherd, SD Gadola, B Mathew, G Ritter, AR Fersht, GS Besra, RR Schmidt, EY Jones, V Cerundolo
Nat Immunol
(2005)
6
The structure of the major transition state for folding of an FF domain from experiment and simulation.
P Jemth, R Day, S Gianni, F Khan, M Allen, V Daggett, AR Fersht
J Mol Biol
(2005)
350
Comparative binding of p53 to its promoter and DNA recognition elements.
RL Weinberg, DB Veprintsev, M Bycroft, AR Fersht
J Mol Biol
(2005)
348
Simulation and experiment at high temperatures: ultrafast folding of a thermophilic protein by nucleation-condensation.
N Ferguson, R Day, CM Johnson, MD Allen, V Daggett, AR Fersht
Journal of molecular biology
(2005)
347
Modulation of binding of DNA to the C-terminal domain of p53 by acetylation.
A Friedler, DB Veprintsev, SMV Freund, KI von Glos, AR Fersht
Structure
(2005)
13
Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor
MR Fernandez-Fernandez, DB Veprintsev, AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2005)
102
Insertion in barnase of a loop sequence from ribonuclease T1
S Vuilleumier, AR Fersht
Eur J Biochem
(2005)
221
Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations
AC Joerger, HC Ang, DB Veprintsev, CM Blair, AR Fersht
Journal of Biological Chemistry
(2005)
280
Binding of natively unfolded HIF-1alpha ODD domain to p53.
N Sánchez-Puig, DB Veprintsev, AR Fersht
Mol Cell
(2005)
17
PFD: a database for the investigation of protein folding kinetics and stability.
KF Fulton, GL Devlin, RA Jodun, L Silvestri, SP Bottomley, AR Fersht, AM Buckle
Nucleic Acids Research
(2005)
33
Effects of heme on the structure of the denatured state and folding kinetics of cytochrome b562
P Garcia, M Bruix, M Rico, S Ciofi-Baffoni, L Banci, MC Ramachandra Shastry, H Roder, T de Lumley Woodyear, CM Johnson, AR Fersht, PD Barker
J Mol Biol
(2004)
346
Binding of Rad51 and Other Peptide Sequences to a Promiscuous, Highly Electrostatic Binding Site in p53*
A Friedler, DB Veprintsev, T Rutherford, KI von Glos, AR Fersht
Journal of Biological Chemistry
(2004)
280
Phi value versus psi analysis.
AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2004)
101
One-state downhill versus conventional protein folding.
N Ferguson, PJ Schartau, TD Sharpe, S Sato, AR Fersht
J Mol Biol
(2004)
344
Relationship of Leffler (Bronsted) alpha values and protein folding Phi values to position of transition-state structures on reaction coordinates (vol 101, pg 14338, 2004)
AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2004)
101
Relationship of Leffler (Bronsted) alpha values and protein folding Phi values to position of transition-state structures on reaction coordinates
AR Fersht
Proc Natl Acad Sci U S A
(2004)
101
Regulation of DNA binding of p53 by its C-terminal domain
RL Weinberg, SMV Freund, DB Veprintsev, M Bycroft, AR Fersht
J Mol Biol
(2004)
342
Cooperative Binding of Tetrameric p53 to DNA
RL Weinberg, DB Veprintsev, AR Fersht
Journal of Molecular Biology
(2004)
341