Determination of the folding transition states of barnase by using ΦI-value-restrained simulations validated by double mutant ΦIJ-values
X Salvatella, CM Dobson, AR Fersht, M Vendruscolo
Proceedings of the National Academy of Sciences
(2005)
102
Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding.
GWN White, S Gianni, JG Grossmann, P Jemth, AR Fersht, V Daggett
J Mol Biol
(2005)
350
The crystal structure of human CD1d with and without alpha-galactosylceramide.
M Koch, VS Stronge, D Shepherd, SD Gadola, B Mathew, G Ritter, AR Fersht, GS Besra, RR Schmidt, EY Jones, V Cerundolo
Nature Immunology
(2005)
6
The structure of the major transition state for folding of an FF domain from experiment and simulation.
P Jemth, R Day, S Gianni, F Khan, M Allen, V Daggett, AR Fersht
Journal of molecular biology
(2005)
350
Comparative binding of p53 to its promoter and DNA recognition elements
RL Weinberg, DB Veprintsev, M Bycroft, AR Fersht
J Mol Biol
(2005)
348
Simulation and Experiment at High Temperatures: Ultrafast Folding of a Thermophilic Protein by Nucleation-condensation
N Ferguson, R Day, CM Johnson, MD Allen, V Daggett, AR Fersht
Journal of Molecular Biology
(2005)
347
Modulation of Binding of DNA to the C-Terminal Domain of p53 by Acetylation
A Friedler, DB Veprintsev, SMV Freund, KI von Glos, AR Fersht
Structure (London, England : 1993)
(2005)
13
Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor
MR Fernandez-Fernandez, DB Veprintsev, AR Fersht
Proceedings of the National Academy of Sciences
(2005)
102
INSERTION IN BARNASE OF A LOOP SEQUENCE FROM RIBONUCLEASE-T1 - INVESTIGATING SEQUENCE AND STRUCTURE ALIGNMENTS BY PROTEIN ENGINEERING
S Vuilleumier, AR Fersht
The FEBS Journal
(2005)
221
Structures of p53 Cancer Mutants and Mechanism of Rescue by Second-site Suppressor Mutations*
AC Joerger, HC Ang, DB Veprintsev, CM Blair, AR Fersht
J Biol Chem
(2005)
280
Binding of natively unfolded HIF-1 alpha ODD domain to p53
N Sánchez-Puig, DB Veprintsev, AR Fersht
Molecular cell
(2005)
17
PFD: a database for the investigation of protein folding kinetics and stability
KF Fulton, GL Devlin, RA Jodun, L Silvestri, SP Bottomley, AR Fersht, AM Buckle
Nucleic Acids Res
(2005)
33
Effects of heme on the structure of the denatured state and folding kinetics of cytochrome b(562)
P Garcia, M Bruix, M Rico, S Ciofi-Baffoni, L Banci, MC Ramachandra Shastry, H Roder, T de Lumley Woodyear, CM Johnson, AR Fersht, PD Barker
J Mol Biol
(2004)
346
Binding of Rad51 and Other Peptide Sequences to a Promiscuous, Highly Electrostatic Binding Site in p53*
A Friedler, DB Veprintsev, T Rutherford, KI von Glos, AR Fersht
Journal of Biological Chemistry
(2004)
280
Phi value versus psi analysis
AR Fersht
Proceedings of the National Academy of Sciences
(2004)
101
One-state Downhill versus Conventional Protein Folding
N Ferguson, PJ Schartau, TD Sharpe, S Sato, AR Fersht
J Mol Biol
(2004)
344
Relationship of Leffler (Bronsted) alpha values and protein folding Phi values to position of transition-state structures on reaction coordinates (vol 101, pg 14338, 2004)
AR Fersht
Proceedings of the National Academy of Sciences
(2004)
101
Relationship of Leffler (Brønsted) α values and protein folding Φ values to position of transition-state structures on reaction coordinates
AR Fersht
Proceedings of the National Academy of Sciences of the United States of America
(2004)
101
Regulation of DNA binding of p53 by its C-terminal domain
RL Weinberg, SMV Freund, DB Veprintsev, M Bycroft, AR Fersht
Journal of molecular biology
(2004)
342
Cooperative binding of tetrameric p53 to DNA
RL Weinberg, DB Veprintsev, AR Fersht
Journal of Molecular Biology
(2004)
341